This is a Validated Antibody Database (VAD) review about human cathepsin B, based on 31 published articles (read how Labome selects the articles), using cathepsin B antibody in all methods. It is aimed to help Labome visitors find the most suited cathepsin B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
cathepsin B synonym: APPS; CPSB; RECEUP

Abcam
mouse monoclonal (CA10)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...
Abcam cathepsin B antibody (Abcam, ab58802) was used in immunohistochemistry - paraffin section on human samples at 1:100. Int J Mol Sci (2022) ncbi
domestic rabbit monoclonal (EPR4323)
  • western blot; human; loading ...; fig 3d
Abcam cathepsin B antibody (Abcam, ab125067) was used in western blot on human samples (fig 3d). Cell Death Dis (2021) ncbi
mouse monoclonal (CA10)
  • western blot; human; loading ...; fig 9c
Abcam cathepsin B antibody (Abcam, ab58802) was used in western blot on human samples (fig 9c). Hum Mol Genet (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3
  • western blot; mouse; fig 3
Abcam cathepsin B antibody (Abcam, ab30443) was used in western blot on human samples (fig 3) and in western blot on mouse samples (fig 3). Aging Cell (2016) ncbi
mouse monoclonal (CA10)
  • immunohistochemistry - frozen section; bovine; 1:200; fig 4
Abcam cathepsin B antibody (Abcam, ab58802) was used in immunohistochemistry - frozen section on bovine samples at 1:200 (fig 4). J Reprod Dev (2015) ncbi
mouse monoclonal (CA10)
  • western blot; human; 1:1000
Abcam cathepsin B antibody (Abcam, ab58802) was used in western blot on human samples at 1:1000. Biochim Biophys Acta (2015) ncbi
mouse monoclonal (CA10)
  • western blot; roundworm ; fig s5
Abcam cathepsin B antibody (Abcam, ab58802) was used in western blot on roundworm samples (fig s5). Autophagy (2014) ncbi
mouse monoclonal (CA10)
  • western blot; human; 1:1000
Abcam cathepsin B antibody (Abcam, ab58802) was used in western blot on human samples at 1:1000. Biochim Biophys Acta (2014) ncbi
mouse monoclonal (CA10)
  • western blot; human; 1:10,000
Abcam cathepsin B antibody (Abcam, ab58802) was used in western blot on human samples at 1:10,000. Diabetes (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-5)
  • western blot; human; loading ...; fig 11c
Santa Cruz Biotechnology cathepsin B antibody (Santa Cruz Biotechnology, sc-365558) was used in western blot on human samples (fig 11c). J Virol (2019) ncbi
mouse monoclonal (H-5)
  • western blot; dogs; fig s4b
Santa Cruz Biotechnology cathepsin B antibody (SantaCruz, sc-365558) was used in western blot on dogs samples (fig s4b). J Cell Sci (2018) ncbi
  • western blot; human; loading ...; fig 6b
In order to report that cathepsin S inhibition sensitizes cancer cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis, Santa Cruz Biotechnology cathepsin B antibody (Santa Cruz, sc-13985) was used in western blot on human samples (fig 6b). Antioxid Redox Signal (2017) ncbi
  • western blot; rat; 1:2000; fig s6
Santa Cruz Biotechnology cathepsin B antibody (Santa Cruz, sc13985) was used in western blot on rat samples at 1:2000 (fig s6). Hum Mol Genet (2015) ncbi
Invitrogen
domestic rabbit polyclonal
  • flow cytometry; mouse; loading ...; fig s4c
Invitrogen cathepsin B antibody (BioLegend, NGZB) was used in flow cytometry on mouse samples (fig s4c). Sci Adv (2020) ncbi
mouse monoclonal (4B11)
  • western blot; human; loading ...; fig 7l
In order to investigate Rab7 and Arl8b crosstalk, Invitrogen cathepsin B antibody (Thermo Fisher, 414800) was used in western blot on human samples (fig 7l). J Cell Biol (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D1C7Y)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology cathepsin B antibody (Cell Signaling Technology, 31718) was used in western blot on mouse samples (fig 5a). Front Immunol (2022) ncbi
domestic rabbit monoclonal (D1C7Y)
  • western blot; mouse; 1:100; loading ...; fig 5a
Cell Signaling Technology cathepsin B antibody (Cell Signaling Technology, 31718) was used in western blot on mouse samples at 1:100 (fig 5a). Sci Adv (2022) ncbi
domestic rabbit monoclonal (D1C7Y)
  • immunohistochemistry; mouse; loading ...; fig 7h
Cell Signaling Technology cathepsin B antibody (Cell Signaling, D1C7Y) was used in immunohistochemistry on mouse samples (fig 7h). Cell Mol Gastroenterol Hepatol (2022) ncbi
domestic rabbit monoclonal (D1C7Y)
  • western blot; mouse; loading ...; fig 6f
Cell Signaling Technology cathepsin B antibody (Cell Signaling Technology, 31718) was used in western blot on mouse samples (fig 6f). Proc Natl Acad Sci U S A (2022) ncbi
domestic rabbit monoclonal (D1C7Y)
  • western blot; mouse; 1:10; loading ...; fig 2a, s3a
Cell Signaling Technology cathepsin B antibody (Cell Signaling, 31718) was used in western blot on mouse samples at 1:10 (fig 2a, s3a). Invest Ophthalmol Vis Sci (2021) ncbi
domestic rabbit monoclonal (D1C7Y)
  • western blot; mouse; 1:1000; loading ...; fig 4e
Cell Signaling Technology cathepsin B antibody (Cell Signaling Technology, 31718S) was used in western blot on mouse samples at 1:1000 (fig 4e). Front Pharmacol (2020) ncbi
domestic rabbit monoclonal (D1C7Y)
  • western blot; mouse; 1:1000; loading ...; fig 2b
  • immunocytochemistry; human; 1:200; loading ...; fig 4c
Cell Signaling Technology cathepsin B antibody (Cell Signaling, 31718) was used in western blot on mouse samples at 1:1000 (fig 2b) and in immunocytochemistry on human samples at 1:200 (fig 4c). Cell Death Dis (2018) ncbi
domestic rabbit monoclonal (D1C7Y)
  • western blot; human; fig 4d
Cell Signaling Technology cathepsin B antibody (Cell Signaling Technology, 31718) was used in western blot on human samples (fig 4d). Cell (2017) ncbi
domestic rabbit monoclonal (D1C7Y)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology cathepsin B antibody (Cell Signaling Technology, 31718S) was used in western blot on human samples at 1:1000 (fig 3b). Mol Cell (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4
Cell Signaling Technology cathepsin B antibody (Cell Signaling, 3373) was used in western blot on human samples (fig 4). Int J Med Sci (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig st1
Cell Signaling Technology cathepsin B antibody (Cell Signaling, 3373) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig st1). Oncotarget (2016) ncbi
BioVision
  • immunohistochemistry; mouse; 1:25; loading ...; fig s6a
In order to discuss mutations that contribute to atopic dermatitis, BioVision cathepsin B antibody (Biovision, 3190-100) was used in immunohistochemistry on mouse samples at 1:25 (fig s6a). J Allergy Clin Immunol (2017) ncbi
  • immunocytochemistry; human; 1:100
BioVision cathepsin B antibody (BioVision, 3190-100) was used in immunocytochemistry on human samples at 1:100. J Huazhong Univ Sci Technolog Med Sci (2014) ncbi
MilliporeSigma
mouse monoclonal (CB59-4B11)
  • western blot; domestic rabbit; 1:1000; fig 2
In order to characterize the role of endolysosomes in skeletal muscle pathology observed in a model of Alzheimer's disease with a cholesterol-fed rabbit, MilliporeSigma cathepsin B antibody (Sigma, C6243) was used in western blot on domestic rabbit samples at 1:1000 (fig 2). Front Aging Neurosci (2016) ncbi
mouse monoclonal (CB59-4B11)
  • western blot; human; 1:1000; fig 7
In order to investigate the effect of Obatoclax in esophageal cancer cells, MilliporeSigma cathepsin B antibody (Sigma, C6243) was used in western blot on human samples at 1:1000 (fig 7). Oncotarget (2016) ncbi
mouse monoclonal (CB59-4B11)
  • western blot; domestic rabbit; fig 3
MilliporeSigma cathepsin B antibody (Sigma, C6243) was used in western blot on domestic rabbit samples (fig 3). Arthritis Res Ther (2015) ncbi
Articles Reviewed
  1. Han X, Li B, Bao J, Wu Z, Chen C, Ni J, et al. Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation. Front Immunol. 2022;13:968639 pubmed publisher
  2. Singh N, Das B, Zhou J, Hu X, Yan R. Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance. Sci Adv. 2022;8:eabo3610 pubmed publisher
  3. Seike T, Boontem P, Yanagi M, Li S, Kido H, Yamamiya D, et al. Hydroxynonenal Causes Hepatocyte Death by Disrupting Lysosomal Integrity in Nonalcoholic Steatohepatitis. Cell Mol Gastroenterol Hepatol. 2022;14:925-944 pubmed publisher
  4. Eninger T, M xfc ller S, Bacioglu M, Schweighauser M, Lambert M, Maia L, et al. Signatures of glial activity can be detected in the CSF proteome. Proc Natl Acad Sci U S A. 2022;119:e2119804119 pubmed publisher
  5. Nishtala K, Panigrahi T, Shetty R, Kumar D, Khamar P, Mohan R, et al. Quantitative Proteomics Reveals Molecular Network Driving Stromal Cell Differentiation: Implications for Corneal Wound Healing. Int J Mol Sci. 2022;23: pubmed publisher
  6. Shyam R, Ogando D, Choi M, Liton P, Bonanno J. Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. Invest Ophthalmol Vis Sci. 2021;62:15 pubmed publisher
  7. Li L, Zhao S, Liu Z, Zhang N, Pang S, Liu J, et al. Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway. Cell Death Dis. 2021;12:220 pubmed publisher
  8. Shen S, Li B, Dai J, Wu Z, He Y, Wen L, et al. BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux. Front Pharmacol. 2020;11:618 pubmed publisher
  9. Fu Y, Ding Y, Wang Q, Zhu F, Tan Y, Lu X, et al. Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2. Sci Adv. 2020;6:eaay9269 pubmed publisher
  10. Drews K, Calgi M, Harrison W, Drews C, Costa Pinheiro P, Shaw J, et al. Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis. J Virol. 2019;93: pubmed publisher
  11. Qiu T, Pei P, Yao X, Jiang L, Wei S, Wang Z, et al. Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway. Cell Death Dis. 2018;9:946 pubmed publisher
  12. Kuchitsu Y, Homma Y, Fujita N, Fukuda M. Rab7 knockout unveils regulated autolysosome maturation induced by glutamine starvation. J Cell Sci. 2018;131: pubmed publisher
  13. Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed publisher
  14. Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed publisher
  15. Huang B, Lin C, Wang C, Kao S. Upregulation of heat shock protein 70 and the differential protein expression induced by tumor necrosis factor-alpha enhances migration and inhibits apoptosis of hepatocellular carcinoma cell HepG2. Int J Med Sci. 2017;14:284-293 pubmed publisher
  16. Marwaha R, Arya S, Jagga D, Kaur H, Tuli A, Sharma M. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol. 2017;216:1051-1070 pubmed publisher
  17. Tanaka Y, Suzuki G, Matsuwaki T, Hosokawa M, Serrano G, Beach T, et al. Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes. Hum Mol Genet. 2017;26:969-988 pubmed publisher
  18. Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed publisher
  19. Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
  20. Chen X, Wagener J, Ghribi O, Geiger J. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Front Aging Neurosci. 2016;8:129 pubmed publisher
  21. Huber M, Falkenberg N, Hauck S, Priller M, Braselmann H, Feuchtinger A, et al. Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer. Oncotarget. 2016;7:44062-44075 pubmed publisher
  22. Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed publisher
  23. Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell. 2016;15:416-27 pubmed publisher
  24. Boddu R, Hull T, Bolisetty S, Hu X, Moehle M, Daher J, et al. Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury. Hum Mol Genet. 2015;24:4078-93 pubmed publisher
  25. Aboelenain M, Kawahara M, Balboula A, Montasser A, Zaabel S, Okuda K, et al. Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle. J Reprod Dev. 2015;61:229-36 pubmed publisher
  26. Kyostio Moore S, Piraino S, Berthelette P, Moran N, Serriello J, Bendele A, et al. Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis. Arthritis Res Ther. 2015;17:5 pubmed publisher
  27. Porter K, Hirt J, Stamer W, Liton P. Autophagic dysregulation in glaucomatous trabecular meshwork cells. Biochim Biophys Acta. 2015;1852:379-85 pubmed publisher
  28. Zhang J, He L, Geng X, Firestone R, Hong Y, Li Y. Anti-cancer effects of novel doxorubicin prodrug PDOX in MCF-7 breast cancer cells. J Huazhong Univ Sci Technolog Med Sci. 2014;34:521-528 pubmed publisher
  29. Guo B, Huang J, Wu W, Feng D, Wang X, Chen Y, et al. The nascent polypeptide-associated complex is essential for autophagic flux. Autophagy. 2014;10:1738-48 pubmed publisher
  30. Porter K, Jeyabalan N, Liton P. MTOR-independent induction of autophagy in trabecular meshwork cells subjected to biaxial stretch. Biochim Biophys Acta. 2014;1843:1054-62 pubmed publisher
  31. Hibbert B, Lavoie J, Ma X, Seibert T, Raizman J, Simard T, et al. Glycogen synthase kinase-3? inhibition augments diabetic endothelial progenitor cell abundance and functionality via cathepsin B: a novel therapeutic opportunity for arterial repair. Diabetes. 2014;63:1410-21 pubmed publisher