This is a Validated Antibody Database (VAD) review about human calcium sensing receptor, based on 21 published articles (read how Labome selects the articles), using calcium sensing receptor antibody in all methods. It is aimed to help Labome visitors find the most suited calcium sensing receptor antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
calcium sensing receptor synonym: CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR

Invitrogen
mouse monoclonal (5C10, ADD)
  • immunohistochemistry - paraffin section; mouse; fig 4b
In order to assess the effects of Fgfr1-3, alphaKlotho, or Fgfr1-4 ablation in the parathyroid glands, Invitrogen calcium sensing receptor antibody (Thermo Fisher, MA1-934) was used in immunohistochemistry - paraffin section on mouse samples (fig 4b). Sci Rep (2017) ncbi
mouse monoclonal (5C10, ADD)
  • western blot; mouse; 1:500; loading ...; fig s3c
In order to perform a genome-wide meta-analysis of urinary magnesium-to-calcium ratio to identify associated common genetic variants in the general population, Invitrogen calcium sensing receptor antibody (Thermo Fischer Scientific, MA1-934) was used in western blot on mouse samples at 1:500 (fig s3c). Pflugers Arch (2017) ncbi
mouse monoclonal (5C10, ADD)
  • immunohistochemistry - paraffin section; human; fig 2a
  • immunocytochemistry; human; loading ...; fig 2g
In order to explore the impact of GPR64 expression on parathyroid hormone secretion, Invitrogen calcium sensing receptor antibody (Thermo Fisher Scientific, MA1-934) was used in immunohistochemistry - paraffin section on human samples (fig 2a) and in immunocytochemistry on human samples (fig 2g). J Bone Miner Res (2017) ncbi
mouse monoclonal (5C10, ADD)
  • western blot; rat; 1:200; loading ...; fig 2e
In order to test if hypoxia-induced activation of Notch signaling upregulates the calcium-sensing receptor in hypoxia-induced pulmonary hypertension, Invitrogen calcium sensing receptor antibody (Thermo Scientific, MA1-934) was used in western blot on rat samples at 1:200 (fig 2e). Hypertens Res (2017) ncbi
mouse monoclonal (5C10, ADD)
  • immunohistochemistry; mouse; 1:500
  • immunohistochemistry; human; 1:500; fig 1
  • immunohistochemistry; rat; 1:500; fig 1
In order to compare expression levels of extracellular calcium-sensing receptor in the rat, mouse, and human kidney, Invitrogen calcium sensing receptor antibody (Thermo, MA1-934) was used in immunohistochemistry on mouse samples at 1:500, in immunohistochemistry on human samples at 1:500 (fig 1) and in immunohistochemistry on rat samples at 1:500 (fig 1). Am J Physiol Renal Physiol (2016) ncbi
domestic rabbit polyclonal
In order to evaluate the potential protein markers of bone metastases in breast cancer patients, Invitrogen calcium sensing receptor antibody (Pierce Bio, PA1-37213) was used . Pathol Oncol Res (2015) ncbi
domestic rabbit polyclonal
In order to correlate choline with the CaSR expression surgical breast specimens, Invitrogen calcium sensing receptor antibody (Affinity BioReagents, PA1-934A) was used . Mol Imaging Biol (2015) ncbi
mouse monoclonal (5C10, ADD)
  • immunohistochemistry - paraffin section; mouse; 1:500
In order to study the localization and role of the calcium-sensing receptor along the nephron, Invitrogen calcium sensing receptor antibody (Thermo scientific, MA1-934) was used in immunohistochemistry - paraffin section on mouse samples at 1:500. Clin Exp Nephrol (2015) ncbi
mouse monoclonal (5C10, ADD)
  • western blot; human
  • immunohistochemistry; mouse; 1:100
  • western blot; mouse
In order to identify the mechanisms of calcium signaling mediated through calcium sensing receptor, Invitrogen calcium sensing receptor antibody (Labome, MA1-934) was used in western blot on human samples , in immunohistochemistry on mouse samples at 1:100 and in western blot on mouse samples . J Biol Chem (2014) ncbi
mouse monoclonal (HL 1499)
  • immunohistochemistry - paraffin section; mouse; 1:100
In order to investigate how serotonin regulates calcium during lactation, Invitrogen calcium sensing receptor antibody (Thermo Scientific, MA1-16940) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. PLoS ONE (2014) ncbi
mouse monoclonal (5C10, ADD)
  • western blot; mouse; 1:500
In order to investigate how serotonin regulates calcium during lactation, Invitrogen calcium sensing receptor antibody (Thermo Scientific, MA1-934) was used in western blot on mouse samples at 1:500. PLoS ONE (2014) ncbi
mouse monoclonal (5C10, ADD)
  • immunocytochemistry; mouse; 1:100
In order to determine which specific macronutrients induced Neuropeptide W secretion, Invitrogen calcium sensing receptor antibody (ABR Affinity BioReagents, MA1-934) was used in immunocytochemistry on mouse samples at 1:100. Peptides (2014) ncbi
mouse monoclonal (5C10, ADD)
  • western blot; mouse; 1:200
  • western blot; rat; 1:200
In order to test the effects of NPS2143 in rats with monocrotaline-induced pulmonary hypertension and mice with chronic hypoxia-induced pulmonary hypertension, Invitrogen calcium sensing receptor antibody (Thermo, MA1?C934,) was used in western blot on mouse samples at 1:200 and in western blot on rat samples at 1:200. Hypertens Res (2014) ncbi
mouse monoclonal (5C10, ADD)
  • immunohistochemistry - frozen section; rat; 1:500
Invitrogen calcium sensing receptor antibody (Pierce Biotechnology, MA1- 934) was used in immunohistochemistry - frozen section on rat samples at 1:500. Exp Physiol (2013) ncbi
Abcam
mouse monoclonal (5C10, ADD)
  • immunohistochemistry - frozen section; human; 1:200; loading ...; fig 5a
Abcam calcium sensing receptor antibody (Abcam, AB-19347) was used in immunohistochemistry - frozen section on human samples at 1:200 (fig 5a). Nutrients (2021) ncbi
mouse monoclonal (5C10, ADD)
  • immunohistochemistry - frozen section; rat; loading ...; fig 2d
Abcam calcium sensing receptor antibody (Abcam, ab19347) was used in immunohistochemistry - frozen section on rat samples (fig 2d). Am J Physiol Renal Physiol (2019) ncbi
mouse monoclonal (5C10, ADD)
  • western blot; human; 1:1000; fig 1
Abcam calcium sensing receptor antibody (Abcam, ab19347) was used in western blot on human samples at 1:1000 (fig 1). J Biol Chem (2016) ncbi
mouse monoclonal (5C10, ADD)
  • immunocytochemistry; rat; 1:100; tbl 1
  • immunohistochemistry - paraffin section; human; 1:200; tbl 1
Abcam calcium sensing receptor antibody (Abcam, ab19347) was used in immunocytochemistry on rat samples at 1:100 (tbl 1) and in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 1). Sci Rep (2016) ncbi
mouse monoclonal (5C10, ADD)
  • western blot; human; 1:1000; fig 5
Abcam calcium sensing receptor antibody (Abcam, ab19347) was used in western blot on human samples at 1:1000 (fig 5). Hum Mol Genet (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (6D4)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 10a
Santa Cruz Biotechnology calcium sensing receptor antibody (Santa Cruz, sc-47741) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 10a). Am J Transl Res (2021) ncbi
mouse monoclonal (6D4)
  • western blot; human; 1:400; fig 2
Santa Cruz Biotechnology calcium sensing receptor antibody (Santa Cruz, sc-47741) was used in western blot on human samples at 1:400 (fig 2). Mol Cancer (2016) ncbi
Novus Biologicals
mouse monoclonal (5C10, ADD)
  • immunohistochemistry - paraffin section; human; 2 ug/ml; fig 1a
Novus Biologicals calcium sensing receptor antibody (Novus, NB-120-19347) was used in immunohistochemistry - paraffin section on human samples at 2 ug/ml (fig 1a). PLoS ONE (2016) ncbi
Articles Reviewed
  1. Noreldin A, Gewaily M, Saadeldin I, Abomughaid M, Khafaga A, Elewa Y. Osteoblast-activating peptide exhibits a specific distribution pattern in mouse ovary and may regulate ovarian steroids and local calcium levels. Am J Transl Res. 2021;13:5796-5814 pubmed
  2. Baumard L, Weerts Z, Masclee A, Keszthelyi D, Michael Titus A, Peiris M. Effect of Obesity on the Expression of Nutrient Receptors and Satiety Hormones in the Human Colon. Nutrients. 2021;13: pubmed publisher
  3. Wu M, Feng Y, Ye G, Han Y, Wang S, Ni H, et al. Calcium-sensing receptor activation attenuates collagen expression in renal proximal tubular epithelial cells. Am J Physiol Renal Physiol. 2019;316:F1006-F1015 pubmed publisher
  4. Kawakami K, Takeshita A, Furushima K, Miyajima M, Hatamura I, Kuro O M, et al. Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease. Sci Rep. 2017;7:40534 pubmed publisher
  5. Corre T, Olinger E, Harris S, Traglia M, Ulivi S, Lenarduzzi S, et al. Common variants in CLDN14 are associated with differential excretion of magnesium over calcium in urine. Pflugers Arch. 2017;469:91-103 pubmed publisher
  6. Balenga N, Azimzadeh P, Hogue J, Staats P, Shi Y, Koh J, et al. Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling. J Bone Miner Res. 2017;32:654-666 pubmed publisher
  7. Guo Q, Xu H, Yang X, Zhao D, Liu S, Sun X, et al. Notch activation of Ca2+-sensing receptor mediates hypoxia-induced pulmonary hypertension. Hypertens Res. 2017;40:117-129 pubmed publisher
  8. Koh J, Hogue J, Sosa J. A Novel Ex Vivo Method for Visualizing Live-Cell Calcium Response Behavior in Intact Human Tumors. PLoS ONE. 2016;11:e0161134 pubmed publisher
  9. Wilkinson R, Young A, Burden R, Williams R, Scott C. A bioavailable cathepsin S nitrile inhibitor abrogates tumor development. Mol Cancer. 2016;15:29 pubmed publisher
  10. Babinsky V, Hannan F, Gorvin C, Howles S, Nesbit M, Rust N, et al. Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein ?-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders. J Biol Chem. 2016;291:10876-85 pubmed publisher
  11. Brennan S, Wilkinson W, Tseng H, Finney B, Monk B, Dibble H, et al. The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR. Sci Rep. 2016;6:21975 pubmed publisher
  12. Graca J, Schepelmann M, Brennan S, Reens J, Chang W, Yan P, et al. Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney. Am J Physiol Renal Physiol. 2016;310:F518-33 pubmed publisher
  13. Hannan F, Howles S, Rogers A, Cranston T, Gorvin C, Babinsky V, et al. Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects. Hum Mol Genet. 2015;24:5079-92 pubmed publisher
  14. Winczura P, Sosińska Mielcarek K, Duchnowska R, Badzio A, Lakomy J, Majewska H, et al. Immunohistochemical Predictors of Bone Metastases in Breast Cancer Patients. Pathol Oncol Res. 2015;21:1229-36 pubmed publisher
  15. Baio G, Rescinito G, Rosa F, Pace D, Boccardo S, Basso L, et al. Correlation between Choline Peak at MR Spectroscopy and Calcium-Sensing Receptor Expression Level in Breast Cancer: A Preliminary Clinical Study. Mol Imaging Biol. 2015;17:548-56 pubmed publisher
  16. Yasuoka Y, Sato Y, Healy J, Nonoguchi H, Kawahara K. pH-sensitive expression of calcium-sensing receptor (CaSR) in type-B intercalated cells of the cortical collecting ducts (CCD) in mouse kidney. Clin Exp Nephrol. 2015;19:771-82 pubmed publisher
  17. Xie R, Dong X, Wong C, Vallon V, Tang B, Sun J, et al. Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion. J Biol Chem. 2014;289:34642-53 pubmed publisher
  18. Laporta J, Keil K, Vezina C, Hernandez L. Peripheral serotonin regulates maternal calcium trafficking in mammary epithelial cells during lactation in mice. PLoS ONE. 2014;9:e110190 pubmed publisher
  19. Li H, Feinle Bisset C, Frisby C, Kentish S, Wittert G, Page A. Gastric neuropeptide W is regulated by meal-related nutrients. Peptides. 2014;62:6-14 pubmed publisher
  20. Guo Q, Huang J, Yamamura A, Yamamura H, Zimnicka A, Fernandez R, et al. Inhibition of the Ca(2+)-sensing receptor rescues pulmonary hypertension in rats and mice. Hypertens Res. 2014;37:116-24 pubmed publisher
  21. Gu Q, Vysotskaya Z, Moss C, Kagira M, Gilbert C. Calcium-sensing receptor in rat vagal bronchopulmonary sensory neurons regulates the function of the capsaicin receptor TRPV1. Exp Physiol. 2013;98:1631-42 pubmed publisher