This is a Validated Antibody Database (VAD) review about human c-IAP2, based on 25 published articles (read how Labome selects the articles), using c-IAP2 antibody in all methods. It is aimed to help Labome visitors find the most suited c-IAP2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
c-IAP2 synonym: AIP1; API2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49; c-IAP2; baculoviral IAP repeat-containing protein 3; IAP homolog C; IAP-1; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1; apoptosis inhibitor 2; cellular inhibitor of apoptosis 2; inhibitor of apoptosis protein 1; mammalian IAP homolog C

R&D Systems
mouse monoclonal (315304)
  • western blot; human; loading ...; fig 1b
  • immunocytochemistry; mouse; loading ...; fig 1d
R&D Systems c-IAP2 antibody (R&D, MAB817) was used in western blot on human samples (fig 1b) and in immunocytochemistry on mouse samples (fig 1d). EMBO Rep (2018) ncbi
mouse monoclonal (315301)
  • western blot; human; loading ...; fig 8b
R&D Systems c-IAP2 antibody (R&D Systems, MAB3400) was used in western blot on human samples (fig 8b). EMBO J (2017) ncbi
goat polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
R&D Systems c-IAP2 antibody (R&D, AF8171) was used in western blot on human samples at 1:1000 (fig 5a). Mol Cell Biol (2017) ncbi
mouse monoclonal (315301)
  • western blot; mouse; fig 6
In order to study the synergistic activity of fludarabine and deguelin in chronic lymphocytic leukemia patient cells in the New Zealand Black Murine model, R&D Systems c-IAP2 antibody (R&D Systems, 315301) was used in western blot on mouse samples (fig 6). PLoS ONE (2016) ncbi
goat polyclonal
  • western blot; human; 1:500; fig s3
R&D Systems c-IAP2 antibody (R&D Systems, AF8171) was used in western blot on human samples at 1:500 (fig s3). Oncotarget (2014) ncbi
mouse monoclonal (315301)
  • western blot; human
  • western blot; chicken
R&D Systems c-IAP2 antibody (R&D Systems, 315301) was used in western blot on human samples and in western blot on chicken samples . Mol Cell Biol (2013) ncbi
Abcam
rabbit monoclonal (E40)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1a
  • western blot; human; 1:1000; loading ...; fig 1d
Abcam c-IAP2 antibody (Abcam, ab32059) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1a) and in western blot on human samples at 1:1000 (fig 1d). Cell Death Dis (2017) ncbi
rabbit monoclonal (E40)
  • immunohistochemistry - paraffin section; human; 1:200; fig 3b
Abcam c-IAP2 antibody (Abcam, E40) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3b). Am J Physiol Gastrointest Liver Physiol (2015) ncbi
rabbit monoclonal (E40)
  • proximity ligation assay; human; fig s2
Abcam c-IAP2 antibody (ABCAM, ab32059) was used in proximity ligation assay on human samples (fig s2). Oncotarget (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human
Abcam c-IAP2 antibody (Abcam, ab137393) was used in immunohistochemistry on human samples . Oncotarget (2014) ncbi
Enzo Life Sciences
rat monoclonal (16E-6-3)
  • western blot; human; loading ...; fig 3a
Enzo Life Sciences c-IAP2 antibody (Enzo Life Sciences, 16E-6-3) was used in western blot on human samples (fig 3a). Nat Microbiol (2017) ncbi
rat monoclonal (16E-6-3)
  • western blot; human; 1:500; fig 4d
Enzo Life Sciences c-IAP2 antibody (Enzo Life Sciences, 16E-6-3) was used in western blot on human samples at 1:500 (fig 4d). Am J Physiol Gastrointest Liver Physiol (2015) ncbi
rat monoclonal (16E-6-3)
  • western blot; human; fig s1
Enzo Life Sciences c-IAP2 antibody (Enzo, ALX-803-341) was used in western blot on human samples (fig s1). EMBO J (2014) ncbi
Abnova
rabbit polyclonal
  • western blot; human; fig 2
Abnova c-IAP2 antibody (Abnova, PAB0253) was used in western blot on human samples (fig 2). Oncotarget (2016) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; loading ...
In order to ask if selinexor, when combined with bortezomib or carfilzomib, attenuates resistance in multiple myeloma samples, Invitrogen c-IAP2 antibody (Fisher, PAS-22997) was used in western blot on human samples . Oncotarget (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (58C7)
  • western blot; human; fig 6e
Cell Signaling Technology c-IAP2 antibody (CST, 3130) was used in western blot on human samples (fig 6e). Cell Death Differ (2018) ncbi
rabbit monoclonal (58C7)
  • western blot; human; loading ...; fig s12b
Cell Signaling Technology c-IAP2 antibody (Cell Signaling, #3130) was used in western blot on human samples (fig s12b). Proc Natl Acad Sci U S A (2018) ncbi
rabbit monoclonal (58C7)
  • other; human; loading ...; fig 4c
Cell Signaling Technology c-IAP2 antibody (Cell Signaling, 3130) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit monoclonal (58C7)
  • western blot; human; loading ...; fig 2a
In order to elucidate how high-risk human papillomavirus alters signaling pathways involved in cell death and growth regulation, Cell Signaling Technology c-IAP2 antibody (Cell signaling, 3130s) was used in western blot on human samples (fig 2a). Front Immunol (2016) ncbi
rabbit monoclonal (58C7)
  • western blot; human; fig 3
Cell Signaling Technology c-IAP2 antibody (Cell Signaling, 3130) was used in western blot on human samples (fig 3). BMC Cancer (2016) ncbi
rabbit monoclonal (58C7)
  • western blot; human; loading ...; fig s4b
Cell Signaling Technology c-IAP2 antibody (Cell Signaling, 3130) was used in western blot on human samples (fig s4b). Cell Death Dis (2016) ncbi
rabbit monoclonal (58C7)
  • western blot; human; fig s6
Cell Signaling Technology c-IAP2 antibody (Cell Signaling Tech, 3130S) was used in western blot on human samples (fig s6). Sci Signal (2016) ncbi
rabbit monoclonal (58C7)
  • western blot; human; loading ...; fig 8a
Cell Signaling Technology c-IAP2 antibody (Cell Signalling, 3130) was used in western blot on human samples (fig 8a). Oncotarget (2015) ncbi
rabbit monoclonal (58C7)
  • western blot; human
Cell Signaling Technology c-IAP2 antibody (Cell Signaling Technologies, 3130) was used in western blot on human samples . PLoS Pathog (2015) ncbi
BD Biosciences
mouse monoclonal (F30-2285)
  • western blot; human; 1:250; fig 5b
In order to show how FADD regulates NF-kappaB activation and promotes ubiquitination of cFLIPL, which induces apoptosis, BD Biosciences c-IAP2 antibody (BD Pharmigen, 552782) was used in western blot on human samples at 1:250 (fig 5b). Sci Rep (2016) ncbi
mouse monoclonal (F30-2285)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences c-IAP2 antibody (BD, F30-2285) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (F30-2285)
  • western blot; human
In order to identify a novel anticancer mechanism that functions through autophagy-mediated necroptosis, BD Biosciences c-IAP2 antibody (BD Biosciences, 552782) was used in western blot on human samples . Oncogene (2014) ncbi
Articles Reviewed
  1. Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2018;: pubmed publisher
  2. Harper C, Woodcock D, Lam C, Garcia Albornoz M, Adamson A, Ashall L, et al. Temperature regulates NF-?B dynamics and function through timing of A20 transcription. Proc Natl Acad Sci U S A. 2018;115:E5243-E5249 pubmed publisher
  3. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  4. Suzuki S, Suzuki T, Mimuro H, Mizushima T, Sasakawa C. Shigella hijacks the glomulin-cIAPs-inflammasome axis to promote inflammation. EMBO Rep. 2018;19:89-101 pubmed publisher
  5. van Wijk S, Fricke F, Herhaus L, Gupta J, Hötte K, Pampaloni F, et al. Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-?B and restricts bacterial proliferation. Nat Microbiol. 2017;2:17066 pubmed publisher
  6. Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
  7. Iurlaro R, Püschel F, León Annicchiarico C, O Connor H, Martin S, Palou Gramón D, et al. Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors. Mol Cell Biol. 2017;37: pubmed publisher
  8. Guicciardi M, Krishnan A, Bronk S, Hirsova P, Griffith T, Gores G. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. Cell Death Dis. 2017;8:e2535 pubmed publisher
  9. Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed
  10. Turner J, Kashyap T, Dawson J, Gomez J, Bauer A, Grant S, et al. XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma. Oncotarget. 2016;7:78896-78909 pubmed publisher
  11. Hrgovic I, Doll M, Kleemann J, Wang X, Zoeller N, Pinter A, et al. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. BMC Cancer. 2016;16:763 pubmed
  12. Klingbeil O, Lesche R, Gelato K, Haendler B, Lejeune P. Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents. Cell Death Dis. 2016;7:e2365 pubmed publisher
  13. Rebolleda N, Losada Fernandez I, Perez Chacon G, Castejon R, Rosado S, Morado M, et al. Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model. PLoS ONE. 2016;11:e0154159 pubmed publisher
  14. Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed publisher
  15. Ranjan K, Pathak C. FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Sci Rep. 2016;6:22787 pubmed publisher
  16. Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed publisher
  17. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  18. Zhang S, Schneider L, Vick B, Grunert M, Jeremias I, Menche D, et al. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Oncotarget. 2015;6:43508-28 pubmed publisher
  19. Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed publisher
  20. Seidelin J, Larsen S, Linnemann D, Vainer B, Coskun M, Troelsen J, et al. Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation. Am J Physiol Gastrointest Liver Physiol. 2015;308:G92-9 pubmed publisher
  21. Choi J, Park B, Chi S, Bae K, Kim S, Cho S, et al. HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization. Oncotarget. 2014;5:10084-99 pubmed
  22. Zhang S, Tang W, Weng S, Liu X, Rao B, Gu J, et al. Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma. Oncotarget. 2014;5:7183-97 pubmed
  23. Takeda A, Oberoi Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed publisher
  24. He W, Wang Q, Srinivasan B, Xu J, Padilla M, Li Z, et al. A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy. Oncogene. 2014;33:3004-13 pubmed publisher
  25. Moreno Garcia M, Sommer K, Rincón Arano H, Brault M, Ninomiya Tsuji J, Matesic L, et al. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-?B activation. Mol Cell Biol. 2013;33:1149-63 pubmed publisher