This is a Validated Antibody Database (VAD) review about human c-IAP1, based on 26 published articles (read how Labome selects the articles), using c-IAP1 antibody in all methods. It is aimed to help Labome visitors find the most suited c-IAP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
c-IAP1 synonym: API1; HIAP2; Hiap-2; MIHB; RNF48; c-IAP1; cIAP1

Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4e, s9e
Abcam c-IAP1 antibody (Abcam, ab2399) was used in western blot on mouse samples at 1:1000 (fig 4e, s9e). Nat Commun (2022) ncbi
domestic rabbit monoclonal (EPR4673)
  • western blot; human; loading ...; fig 5b
Abcam c-IAP1 antibody (Abcam, ab108361) was used in western blot on human samples (fig 5b). Int J Mol Sci (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Abcam c-IAP1 antibody (Abcam, ab2399) was used in western blot on human samples (fig 5). J Cancer (2016) ncbi
domestic rabbit monoclonal (EPR4673)
  • western blot; human
Abcam c-IAP1 antibody (Abcam, ab108361) was used in western blot on human samples . J Biol Chem (2015) ncbi
domestic rabbit monoclonal (EPR4673)
  • immunohistochemistry; human
Abcam c-IAP1 antibody (Abcam, ab108361) was used in immunohistochemistry on human samples . Oncotarget (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-4)
  • western blot; human; loading ...; fig s6a
Santa Cruz Biotechnology c-IAP1 antibody (Santa Cruz, sc-271419) was used in western blot on human samples (fig s6a). Sci Adv (2021) ncbi
mouse monoclonal (F-4)
  • western blot; human; fig s4
In order to investigate the role of RIPK1 in response to endoplasmic reticulum stress, Santa Cruz Biotechnology c-IAP1 antibody (Santa Cruz Biotechnology, sc-271419) was used in western blot on human samples (fig s4). Autophagy (2015) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; loading ...
In order to ask if selinexor, when combined with bortezomib or carfilzomib, attenuates resistance in multiple myeloma samples, Invitrogen c-IAP1 antibody (Fisher, PAS-29085) was used in western blot on human samples . Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D5G9)
  • western blot; human; fig 1j
Cell Signaling Technology c-IAP1 antibody (Cell Signaling Technology, D5G9) was used in western blot on human samples (fig 1j). elife (2021) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; fig 6a
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, 7065) was used in western blot on human samples (fig 6a). Oncogenesis (2021) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; loading ...
Cell Signaling Technology c-IAP1 antibody (Cell signaling, 7065) was used in western blot on human samples . Cell Commun Signal (2020) ncbi
domestic rabbit monoclonal (D5G9)
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, D5G9) was used . Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology c-IAP1 antibody (Cell Signaling Technology, 4952) was used in western blot on mouse samples at 1:1000 (fig 5a). J Cell Sci (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2h
Cell Signaling Technology c-IAP1 antibody (Cell Signalling Technology, 4952) was used in western blot on mouse samples at 1:1000 (fig 2h). Redox Biol (2019) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; fig s5c
Cell Signaling Technology c-IAP1 antibody (CST, 7065) was used in western blot on human samples (fig s5c). Cell Death Differ (2019) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology c-IAP1 antibody (Cell Signaling Technology, 7065) was used in western blot on human samples (fig 5a). Cell Death Dis (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2b
In order to observe that chronic presence of internalized Escherichia coli leads to enhanced oncogenicity in colon cancer cells, Cell Signaling Technology c-IAP1 antibody (cell signalling, 4952) was used in western blot on human samples (fig 2b). Cell Death Dis (2017) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; loading ...; fig 2a
In order to elucidate how high-risk human papillomavirus alters signaling pathways involved in cell death and growth regulation, Cell Signaling Technology c-IAP1 antibody (Cell signaling, 7065p) was used in western blot on human samples (fig 2a). Front Immunol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, 4952) was used in western blot on human samples (fig 3). BMC Cancer (2016) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; loading ...; fig s4b
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, 7065) was used in western blot on human samples (fig s4b). Cell Death Dis (2016) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; loading ...
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, 7065) was used in western blot on human samples . Cell Microbiol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
  • western blot; mouse; fig 1
Cell Signaling Technology c-IAP1 antibody (Cell Signaling Tech, 4952) was used in western blot on human samples (fig 1) and in western blot on mouse samples (fig 1). Oncogenesis (2016) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; fig 4
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, 7065) was used in western blot on human samples (fig 4). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, 4952) was used in western blot on human samples (fig 4). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human
Cell Signaling Technology c-IAP1 antibody (Cell Signaling Technologies, 7065) was used in western blot on human samples . PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (D5G9)
  • western blot; human; 1:500
Cell Signaling Technology c-IAP1 antibody (Cell Signaling, #7065) was used in western blot on human samples at 1:500. Oncotarget (2014) ncbi
BD Biosciences
mouse (B75-1)
  • western blot; human; 1:1000; loading ...; fig 5a
BD Biosciences c-IAP1 antibody (Pharmingen, B75-1) was used in western blot on human samples at 1:1000 (fig 5a). Mol Cell Biol (2017) ncbi
Articles Reviewed
  1. Zhang X, Xiong T, Gao L, Wang Y, Liu L, Tian T, et al. Extracellular fibrinogen-binding protein released by intracellular Staphylococcus aureus suppresses host immunity by targeting TRAF3. Nat Commun. 2022;13:5493 pubmed publisher
  2. Jeong D, Kim H, Kim H, Kang M, Jung H, Oh Y, et al. Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. elife. 2021;10: pubmed publisher
  3. Nagamura Y, Miyazaki M, Nagano Y, Yuki M, Fukami K, Yanagihara K, et al. PLEKHA5 regulates the survival and peritoneal dissemination of diffuse-type gastric carcinoma cells with Met gene amplification. Oncogenesis. 2021;10:25 pubmed publisher
  4. Kitamura Y, Kanaya N, Moleirinho S, Du W, Reinshagen C, Attia N, et al. Anti-EGFR VHH-armed death receptor ligand-engineered allogeneic stem cells have therapeutic efficacy in diverse brain metastatic breast cancers. Sci Adv. 2021;7: pubmed publisher
  5. Lomphithak T, Choksi S, Mutirangura A, Tohtong R, Tencomnao T, Usubuchi H, et al. Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma. Cell Commun Signal. 2020;18:161 pubmed publisher
  6. Kawalkowska J, Ogbechi J, Venables P, Williams R. cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs. Sci Adv. 2019;5:eaaw5422 pubmed publisher
  7. Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
  8. Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway. Redox Biol. 2019;20:261-274 pubmed publisher
  9. Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
  10. Wang H, Bu L, Wang C, Zhang Y, Zhou H, Zhang X, et al. The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein-Barr virus by inhibiting the molecular chaperone function of Hsp70. Cell Death Dis. 2018;9:734 pubmed publisher
  11. Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  12. Iurlaro R, Püschel F, León Annicchiarico C, O Connor H, Martin S, Palou Gramón D, et al. Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors. Mol Cell Biol. 2017;37: pubmed publisher
  13. Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed
  14. Turner J, Kashyap T, Dawson J, Gomez J, Bauer A, Grant S, et al. XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma. Oncotarget. 2016;7:78896-78909 pubmed publisher
  15. Hrgovic I, Doll M, Kleemann J, Wang X, Zoeller N, Pinter A, et al. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. BMC Cancer. 2016;16:763 pubmed
  16. Klingbeil O, Lesche R, Gelato K, Haendler B, Lejeune P. Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents. Cell Death Dis. 2016;7:e2365 pubmed publisher
  17. Cheng S, Jiang X, Ding C, Du C, Owusu Ansah K, Weng X, et al. Expression and Critical Role of Interleukin Enhancer Binding Factor 2 in Hepatocellular Carcinoma. Int J Mol Sci. 2016;17: pubmed publisher
  18. Zeng W, Liu Q, Chen Z, Wu X, Zhong Y, Wu J. Silencing of hERG1 Gene Inhibits Proliferation and Invasion, and Induces Apoptosis in Human Osteosarcoma Cells by Targeting the NF-?B Pathway. J Cancer. 2016;7:746-57 pubmed publisher
  19. Waguia Kontchou C, Tzivelekidis T, Gentle I, Hacker G. Infection of epithelial cells with Chlamydia trachomatis inhibits TNF-induced apoptosis at the level of receptor internalization while leaving non-apoptotic TNF-signalling intact. Cell Microbiol. 2016;18:1583-1595 pubmed publisher
  20. West A, Martin B, Andrews D, Hogg S, Banerjee A, Grigoriadis G, et al. The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock. Oncogenesis. 2016;5:e216 pubmed publisher
  21. Monian P, Jiang X. The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem. 2016;291:2379-88 pubmed publisher
  22. Luan Q, Jin L, Jiang C, Tay K, Lai F, Liu X, et al. RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy. Autophagy. 2015;11:975-94 pubmed publisher
  23. Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed publisher
  24. Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, et al. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. J Biol Chem. 2015;290:10395-405 pubmed publisher
  25. Zhang S, Tang W, Weng S, Liu X, Rao B, Gu J, et al. Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma. Oncotarget. 2014;5:7183-97 pubmed
  26. Luk S, Xue H, Cheng H, Lin D, Gout P, Fazli L, et al. The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis. Oncotarget. 2014;5:6896-908 pubmed