This is a Validated Antibody Database (VAD) review about human angiopoietin 2, based on 7 published articles (read how Labome selects the articles), using angiopoietin 2 antibody in all methods. It is aimed to help Labome visitors find the most suited angiopoietin 2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
angiopoietin 2 synonym: AGPT2; ANG2

Santa Cruz Biotechnology
mouse monoclonal (F-1)
  • western blot; human; fig 1C
Santa Cruz Biotechnology angiopoietin 2 antibody (Santa Cruz, sc-74403) was used in western blot on human samples (fig 1C). J Hematol Oncol (2017) ncbi
mouse monoclonal (H-11)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Santa Cruz Biotechnology angiopoietin 2 antibody (santa Cruz, sc-74402) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). Cancer Gene Ther (2016) ncbi
mouse monoclonal (F-1)
  • immunohistochemistry - paraffin section; human; fig 1
In order to characterize angiogenic markers and protein and gene expression in oral squamous cell carcinoma, Santa Cruz Biotechnology angiopoietin 2 antibody (Santa Cruz, F-1) was used in immunohistochemistry - paraffin section on human samples (fig 1). Head Face Med (2015) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; human; 1:200; loading ...; fig 2h
  • western blot; human; 1:1000
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2d
  • immunocytochemistry; mouse; 1:200; fig s4f
  • western blot; mouse; 1:1000
In order to study the role of endothelial cell exocytosis in cerebral cavernous malformation disease progression, Abcam angiopoietin 2 antibody (Abcam, ab8452) was used in immunohistochemistry - frozen section on human samples at 1:200 (fig 2h), in western blot on human samples at 1:1000, in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 2d), in immunocytochemistry on mouse samples at 1:200 (fig s4f) and in western blot on mouse samples at 1:1000. Nat Med (2016) ncbi
domestic rabbit monoclonal (EPR2891(2))
  • western blot; human; fig 4
Abcam angiopoietin 2 antibody (Abcam, ab155106) was used in western blot on human samples (fig 4). Endocr Relat Cancer (2016) ncbi
R&D Systems
domestic goat polyclonal
  • immunocytochemistry; human; loading ...; fig 3c
  • western blot; human; loading ...; fig 4a
R&D Systems angiopoietin 2 antibody (R&D Systems, AF623) was used in immunocytochemistry on human samples (fig 3c) and in western blot on human samples (fig 4a). Sci Rep (2017) ncbi
domestic goat polyclonal
  • immunohistochemistry - frozen section; human; 1:100; loading ...; fig 2h
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2d
  • immunocytochemistry; mouse; 1:100; fig s4f
In order to study the role of endothelial cell exocytosis in cerebral cavernous malformation disease progression, R&D Systems angiopoietin 2 antibody (R&D, AF623) was used in immunohistochemistry - frozen section on human samples at 1:100 (fig 2h), in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2d) and in immunocytochemistry on mouse samples at 1:100 (fig s4f). Nat Med (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:200; fig 6
In order to report angiopoietin-2 as a target in both naive and bevacizumab-treated glioblastoma, Invitrogen angiopoietin 2 antibody (Pierce Biotechnology, PA5?\27297) was used in immunohistochemistry on human samples at 1:200 (fig 6). EMBO Mol Med (2016) ncbi
Articles Reviewed
  1. Retzlaff J, Thamm K, Ghosh C, Ziegler W, Haller H, Parikh S, et al. Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis. Sci Rep. 2017;7:44113 pubmed publisher
  2. Gravina G, Mancini A, Marampon F, Colapietro A, Delle Monache S, Sferra R, et al. The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma. J Hematol Oncol. 2017;10:5 pubmed publisher
  3. Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
  4. Li C, Li Q, Cai Y, He Y, Lan X, Wang W, et al. Overexpression of angiopoietin 2 promotes the formation of oral squamous cell carcinoma by increasing epithelial-mesenchymal transition-induced angiogenesis. Cancer Gene Ther. 2016;23:295-302 pubmed publisher
  5. Han H, Kim B, Lee J, Kang S, Kim J, Cho N. Angiopoietin-2 promotes ER+ breast cancer cell survival in bone marrow niche. Endocr Relat Cancer. 2016;23:609-23 pubmed publisher
  6. Scholz A, Harter P, Cremer S, Yalcin B, Gurnik S, Yamaji M, et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med. 2016;8:39-57 pubmed publisher
  7. Jung S, Sielker S, Purcz N, Sproll C, Acil Y, Kleinheinz J. Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression. Head Face Med. 2015;11:19 pubmed publisher