This is a Validated Antibody Database (VAD) review about human alpha-catenin, based on 35 published articles (read how Labome selects the articles), using alpha-catenin antibody in all methods. It is aimed to help Labome visitors find the most suited alpha-catenin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
alpha-catenin synonym: CAP102; MDPT2

Invitrogen
mouse monoclonal (alpha-CAT-7A4)
  • immunocytochemistry; human; 1:250; loading ...; fig 4b
Invitrogen alpha-catenin antibody (Thermo Fisher Scientific, 13-9700) was used in immunocytochemistry on human samples at 1:250 (fig 4b). Proc Natl Acad Sci U S A (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; Xenopus laevis; loading ...; fig 2a
In order to investigate the regulation of cellular junctions and mechanical forces at adherens junctions, Invitrogen alpha-catenin antibody (Thermo Scientific, PA1-25081) was used in immunohistochemistry on Xenopus laevis samples (fig 2a). Sci Rep (2017) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry; rat; 1:100
In order to study the role of plastin 3 in ectoplasmic specialization dynamics during spermatogenesis in the rat testis, Invitrogen alpha-catenin antibody (Invitrogen, 13-9700) was used in immunohistochemistry on rat samples at 1:100. FASEB J (2015) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - paraffin section; human; 1:100
In order to discuss catenin expression in feline mammary tissues, Invitrogen alpha-catenin antibody (Zymed/Invitrogen, alphaCAT-7A4) was used in immunohistochemistry - paraffin section on human samples at 1:100. Anticancer Res (2015) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - paraffin section; human; 1:100
Invitrogen alpha-catenin antibody (Zymed Inc, alpha CAT-7A4) was used in immunohistochemistry - paraffin section on human samples at 1:100. Clin Exp Metastasis (2015) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry; rat; 1:100
In order to report that Rai14 regulates actin filaments organization in Sertoli cells during the epithelial cycle, Invitrogen alpha-catenin antibody (Zymed/Invitrogen, 13-9700) was used in immunohistochemistry on rat samples at 1:100. PLoS ONE (2013) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunocytochemistry; mouse; 1:100; loading ...; fig s5
  • immunohistochemistry; mouse; 1:100; loading ...; fig s3h
In order to investigate the role of Merlin in adheren junction establishment, Invitrogen alpha-catenin antibody (Zymed, aCAT-7A4) was used in immunocytochemistry on mouse samples at 1:100 (fig s5) and in immunohistochemistry on mouse samples at 1:100 (fig s3h). Dev Cell (2010) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - paraffin section; human; 1:100
In order to determine the expression of several adhesion molecules and MUC1 in samples from patients with unifocal or multifocal bladder urothelial cell carcinoma in situ, Invitrogen alpha-catenin antibody (Zymed, alpha Cat-7A4) was used in immunohistochemistry - paraffin section on human samples at 1:100. Int J Surg Pathol (2009) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - frozen section; rat
In order to study the spatial and functional relationships between tight and adherens junctions in the sinus endothelial cells of rat spleen, Invitrogen alpha-catenin antibody (Zymed Laboratories, 13-9700) was used in immunohistochemistry - frozen section on rat samples . Histochem Cell Biol (2008) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
In order to quantify the expression of E-cadherin and a- and b-catenins that form the cadherin-catenin complex in tumoral vascular invasion in metastatic sentinel lymph node patients, Invitrogen alpha-catenin antibody (Zymed, a CAT-7a4) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). Pathol Res Pract (2007) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - frozen section; mouse; 1:100
In order to examine the involvement of catenin-cadherin mediated adhesion in the axonal projection of olfactory sensory neuron (OSN) axons, Invitrogen alpha-catenin antibody (Invitrogen, 13-9700) was used in immunohistochemistry - frozen section on mouse samples at 1:100. J Comp Neurol (2006) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunocytochemistry; mouse; fig 1
  • western blot; mouse; fig 1
In order to identify and characterize a novel classical cadherin adhesion system, Invitrogen alpha-catenin antibody (Zymed, alphaCAT-7A4) was used in immunocytochemistry on mouse samples (fig 1) and in western blot on mouse samples (fig 1). J Cell Sci (2005) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - frozen section; human
In order to investigate the effect of the plakoglobin mutation in Naxos disease on connexin43, Invitrogen alpha-catenin antibody (Zymed, 7A4) was used in immunohistochemistry - frozen section on human samples . Heart Rhythm (2004) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - paraffin section; human; 1:50; tbl 1
In order to measure the E- and N-cadherin and beta- and alpha-catenin expression in benign and malignant epithelial neoplasms of the ovary and correlate expression with tumor staging, histological grade, and presence of metastases during evolution, Invitrogen alpha-catenin antibody (ZYMED, alphaCAT-7A4) was used in immunohistochemistry - paraffin section on human samples at 1:50 (tbl 1). Gynecol Oncol (2004) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - paraffin section; human; 1:100; tbl 4
In order to elucidate the relation between the macroscopic growth patterns of gastric carcinoma and the abnormal expression of E-cadherin and alpha- and beta-catenins, Invitrogen alpha-catenin antibody (Zymed, [alpha]-CAT-7A4) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 4). J Clin Gastroenterol (2004) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • western blot; mouse; fig 8
In order to examine the effect of the Apc(Min) mutation upon cell-cell adhesion, Invitrogen alpha-catenin antibody (Zymed Laboratories, clone alphaCAT-7A4) was used in western blot on mouse samples (fig 8). J Biol Chem (2001) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunocytochemistry; human
In order to propose that an endothelial-dependent step of transient and focal disruption of the vascular endothelial-cadherin complex occurs during leukocyte transmigration, Invitrogen alpha-catenin antibody (Zymed, CAT-7A4) was used in immunocytochemistry on human samples . J Cell Biol (2000) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • immunohistochemistry - frozen section; human
In order to validate the use of polymerase chain reaction-amplified full-length cDNA as a substitute for mRNA in nucleic acid array and gene expression analysis, Invitrogen alpha-catenin antibody (Zymed, aCAT-7A4) was used in immunohistochemistry - frozen section on human samples . Invest Ophthalmol Vis Sci (1999) ncbi
mouse monoclonal (alpha-CAT-7A4)
  • western blot; human
In order to elucidate the transformation of normal squamous epithelium to squamous intraepithelial lesions using the uterine cervix, Invitrogen alpha-catenin antibody (Zymed, aCAT-7A4) was used in western blot on human samples . Am J Pathol (1999) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-11)
  • western blot; human; loading ...; fig 5a, 5b
Santa Cruz Biotechnology alpha-catenin antibody (Santa Cruz, sc-9988) was used in western blot on human samples (fig 5a, 5b). J Biol Chem (2021) ncbi
mouse monoclonal (G-11)
  • immunocytochemistry; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 2b, s2b
Santa Cruz Biotechnology alpha-catenin antibody (Santa Cruz, sc-9988) was used in immunocytochemistry on human samples (fig 2c) and in western blot on human samples (fig 2b, s2b). iScience (2020) ncbi
mouse monoclonal (G-11)
  • immunocytochemistry; human; fig 1f
  • western blot; human; fig 1g
Santa Cruz Biotechnology alpha-catenin antibody (Santa, sc-9988) was used in immunocytochemistry on human samples (fig 1f) and in western blot on human samples (fig 1g). J Mol Cell Cardiol (2019) ncbi
mouse monoclonal (G-11)
  • immunohistochemistry; human; 1:200; loading ...; fig 2e
  • western blot; human; loading ...; fig 1c
  • immunohistochemistry; mouse; 1:200; loading ...; fig 8f
  • western blot; mouse; loading ...; fig 8d
Santa Cruz Biotechnology alpha-catenin antibody (Santa Cruz, SC-9988) was used in immunohistochemistry on human samples at 1:200 (fig 2e), in western blot on human samples (fig 1c), in immunohistochemistry on mouse samples at 1:200 (fig 8f) and in western blot on mouse samples (fig 8d). Redox Biol (2017) ncbi
Abcam
domestic rabbit monoclonal (EP1793Y)
  • western blot; human; 1:5000; loading ...; fig 4d
Abcam alpha-catenin antibody (Abcam, ab51032) was used in western blot on human samples at 1:5000 (fig 4d). Aging (Albany NY) (2016) ncbi
domestic rabbit monoclonal (EP1793Y)
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig ev3a3
Abcam alpha-catenin antibody (Abcam, ab51032) was used in immunohistochemistry - paraffin section on mouse samples at 1:2000 (fig ev3a3). EMBO Rep (2015) ncbi
domestic rabbit monoclonal (EP1793Y)
  • immunocytochemistry; human
  • western blot; human
In order to identify the role of obscurins during breast carcinogenesis, Abcam alpha-catenin antibody (Abcam, ab51032) was used in immunocytochemistry on human samples and in western blot on human samples . Oncogene (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s1d
  • immunocytochemistry; human; 1:200; loading ...; fig 4g
  • western blot; human; 1:1000; loading ...; fig 2a
Cell Signaling Technology alpha-catenin antibody (Cell Signaling, 3236) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s1d), in immunocytochemistry on human samples at 1:200 (fig 4g) and in western blot on human samples at 1:1000 (fig 2a). J Biol Chem (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology alpha-catenin antibody (Cell Signaling, 3236) was used in western blot on mouse samples (fig 1b). Nature (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s2b
Cell Signaling Technology alpha-catenin antibody (Cell Signaling, 3236) was used in western blot on human samples (fig s2b). J Mol Cell Biol (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 6h
Cell Signaling Technology alpha-catenin antibody (Cell Signaling, 3236) was used in immunohistochemistry on mouse samples at 1:200 (fig 6h). J Cell Biol (2018) ncbi
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology alpha-catenin antibody (Cell signaling, 2951S) was used in western blot on human samples (fig 1b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (23B2)
  • immunocytochemistry; human; loading ...
  • western blot; human; loading ...; fig s4b
In order to investigate the role of CD73 in endometrial cancer, Cell Signaling Technology alpha-catenin antibody (Cell Signaling, 23B2) was used in immunocytochemistry on human samples and in western blot on human samples (fig s4b). J Clin Invest (2016) ncbi
Bioworld
  • western blot; human; fig 5
Bioworld alpha-catenin antibody (Bioworld Tech, BS4739) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
BD Biosciences
mouse monoclonal (30/?-Catenin)
  • immunoprecipitation; human; fig 2
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 2
In order to study the interaction between EGFR and delta catenin, which leads to delta catenin phosphorylation and EGFR signaling enhancement, BD Biosciences alpha-catenin antibody (BD Bioscience, 611537) was used in immunoprecipitation on human samples (fig 2), in immunocytochemistry on human samples (fig 2) and in western blot on human samples (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (30/?-Catenin)
  • western blot; human; 1:800
BD Biosciences alpha-catenin antibody (BD Transduction Labs, 611537) was used in western blot on human samples at 1:800. J Biol Chem (2015) ncbi
Articles Reviewed
  1. Goswami S, Balasubramanian I, D Agostino L, Bandyopadhyay S, Patel R, Avasthi S, et al. RAB11A-mediated YAP localization to adherens and tight junctions is essential for colonic epithelial integrity. J Biol Chem. 2021;297:100848 pubmed publisher
  2. Ear J, Abd El Hafeez A, Roy S, Ngo T, Rajapakse N, Choi J, et al. A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding. J Biol Chem. 2021;296:100493 pubmed publisher
  3. Wijshake T, Zou Z, Chen B, Zhong L, Xiao G, Xie Y, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  4. Ear J, Saklecha A, Rajapakse N, Choi J, Ghassemian M, Kufareva I, et al. Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. iScience. 2020;23:100859 pubmed publisher
  5. Padmanaban V, Krol I, Suhail Y, Szczerba B, Aceto N, Bader J, et al. E-cadherin is required for metastasis in multiple models of breast cancer. Nature. 2019;573:439-444 pubmed publisher
  6. Wang R, Yu R, Zhu C, Lin H, Lu X, Wang H. Tubulin detyrosination promotes human trophoblast syncytium formation. J Mol Cell Biol. 2019;: pubmed publisher
  7. Weng J, Yu L, Chen Z, Su H, Yu S, Zhang Y, et al. β-Catenin phosphorylation at Y654 and Y142 is crucial for high mobility group box-1 protein-induced pulmonary vascular hyperpermeability. J Mol Cell Cardiol. 2019;127:174-184 pubmed publisher
  8. Hoefert J, Bjerke G, Wang D, Yi R. The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. J Cell Biol. 2018;217:2185-2204 pubmed publisher
  9. Herbomel G, Hatte G, Roul J, Padilla Parra S, Tassan J, Tramier M. Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos. Sci Rep. 2017;7:45058 pubmed publisher
  10. Chattopadhyay R, Raghavan S, Rao G. Resolvin D1 via prevention of ROS-mediated SHP2 inactivation protects endothelial adherens junction integrity and barrier function. Redox Biol. 2017;12:438-455 pubmed publisher
  11. Zeng L, Yang X, Wen Y, Mail S, Wang M, Zhang M, et al. Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma. Aging (Albany NY). 2016;8:1236-49 pubmed publisher
  12. Zhang M, Linghu E, Zhan Q, He T, Cao B, Brock M, et al. Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling. Oncotarget. 2016;7:17957-69 pubmed publisher
  13. He Y, Ryu T, Shrestha N, Yuan T, Kim H, Shrestha H, et al. Interaction of EGFR to δ-catenin leads to δ-catenin phosphorylation and enhances EGFR signaling. Sci Rep. 2016;6:21207 pubmed publisher
  14. Al Thawadi H, Abu Kaoud N, Al Farsi H, Hoarau Véchot J, Rafii S, Rafii A, et al. VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells. Oncotarget. 2016;7:5289-305 pubmed publisher
  15. Bowser J, Blackburn M, Shipley G, Molina J, Dunner K, Broaddus R. Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. J Clin Invest. 2016;126:220-38 pubmed publisher
  16. Dietrich J, Panavaite L, Günther S, Wennekamp S, Groner A, Pigge A, et al. Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. EMBO Rep. 2015;16:1005-21 pubmed publisher
  17. Li N, Mruk D, Wong C, Lee W, Han D, Cheng C. Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis. FASEB J. 2015;29:3788-805 pubmed publisher
  18. Figueira A, Gomes C, Vilhena H, Miranda S, Carvalheira J, de Matos A, et al. Characterization of α-, β- and p120-Catenin Expression in Feline Mammary Tissues and their Relation with E- and P-Cadherin. Anticancer Res. 2015;35:3361-9 pubmed
  19. Yuan L, Seong E, Beuscher J, Arikkath J. δ-Catenin Regulates Spine Architecture via Cadherin and PDZ-dependent Interactions. J Biol Chem. 2015;290:10947-57 pubmed publisher
  20. da Silva S, Morand G, Alobaid F, Hier M, Mlynarek A, Alaoui Jamali M, et al. Epithelial-mesenchymal transition (EMT) markers have prognostic impact in multiple primary oral squamous cell carcinoma. Clin Exp Metastasis. 2015;32:55-63 pubmed publisher
  21. Shriver M, Stroka K, Vitolo M, Martin S, Huso D, Konstantopoulos K, et al. Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis. Oncogene. 2015;34:4248-59 pubmed publisher
  22. Qian X, Mruk D, Cheng C. Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*. PLoS ONE. 2013;8:e60656 pubmed publisher
  23. Gladden A, Hebert A, Schneeberger E, McClatchey A. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010;19:727-39 pubmed publisher
  24. Patriarca C, Colombo P, Pio Taronna A, Wesseling J, Franchi G, Guddo F, et al. Cell discohesion and multifocality of carcinoma in situ of the bladder: new insight from the adhesion molecule profile (e-cadherin, Ep-CAM, and MUC1). Int J Surg Pathol. 2009;17:99-106 pubmed publisher
  25. Uehara K, Uehara A. Localization of claudin-5 and ZO-1 in rat spleen sinus endothelial cells. Histochem Cell Biol. 2008;129:95-103 pubmed
  26. Canavese G, Bernardi A, Candelaresi G, Lovadina P, Amerio S, Rossetti V, et al. Expression of the E-cadherin-catenins complex in sentinel node is related to tumor morphology but not to spread to nonsentinel nodes. Pathol Res Pract. 2007;203:517-23 pubmed
  27. Akins M, Greer C. Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion. J Comp Neurol. 2006;499:979-89 pubmed
  28. Kim Y, Sauer C, Testa K, Wahl J, Svoboda R, Johnson K, et al. Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex. J Cell Sci. 2005;118:3883-94 pubmed
  29. Kaplan S, Gard J, Protonotarios N, Tsatsopoulou A, Spiliopoulou C, Anastasakis A, et al. Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease). Heart Rhythm. 2004;1:3-11 pubmed
  30. Marques F, Fonsechi Carvasan G, de Angelo Andrade L, Bottcher Luiz F. Immunohistochemical patterns for alpha- and beta-catenin, E- and N-cadherin expression in ovarian epithelial tumors. Gynecol Oncol. 2004;94:16-24 pubmed
  31. Song S, Kim S, Kim D, Son H, Rhee J, Kim Y. Abnormal expression of E-cadherin in early gastric carcinoma: its relationship with macroscopic growth patterns and catenin alpha and beta. J Clin Gastroenterol. 2004;38:252-9 pubmed
  32. Carothers A, Melstrom K, Mueller J, Weyant M, Bertagnolli M. Progressive changes in adherens junction structure during intestinal adenoma formation in Apc mutant mice. J Biol Chem. 2001;276:39094-102 pubmed
  33. Allport J, Muller W, Luscinskas F. Monocytes induce reversible focal changes in vascular endothelial cadherin complex during transendothelial migration under flow. J Cell Biol. 2000;148:203-16 pubmed
  34. Spirin K, Ljubimov A, Castellon R, Wiedoeft O, Marano M, Sheppard D, et al. Analysis of gene expression in human bullous keratopathy corneas containing limiting amounts of RNA. Invest Ophthalmol Vis Sci. 1999;40:3108-15 pubmed
  35. de Boer C, van Dorst E, van Krieken H, Jansen van Rhijn C, Warnaar S, Fleuren G, et al. Changing roles of cadherins and catenins during progression of squamous intraepithelial lesions in the uterine cervix. Am J Pathol. 1999;155:505-15 pubmed