This is a Validated Antibody Database (VAD) review about human aggrecan, based on 50 published articles (read how Labome selects the articles), using aggrecan antibody in all methods. It is aimed to help Labome visitors find the most suited aggrecan antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
aggrecan synonym: AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK; SSOAOD

Invitrogen
mouse monoclonal (BC-3)
  • immunocytochemistry; human; 1:200; loading ...; fig 1g
Invitrogen aggrecan antibody (Thermo Fisher Scientific, MA3-16888) was used in immunocytochemistry on human samples at 1:200 (fig 1g). Cell Res (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1 ug/ml; loading ...; fig s3b
Invitrogen aggrecan antibody (Thermo Fisher, PA1-1746) was used in western blot on human samples at 1 ug/ml (fig s3b). Arterioscler Thromb Vasc Biol (2019) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry; horses; 1:30; loading ...; tbl 1
In order to compare 3D co-culture constructs of primary equine mesenchymal stem cells and meniscus cells for their qualification to be applied for meniscus tissue engineering, Invitrogen aggrecan antibody (Affinity Bioreagents, MA3- 16888) was used in immunohistochemistry on horses samples at 1:30 (tbl 1). Tissue Eng Part A (2017) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 3p
In order to generate and characterize bioreactor-cultivated nasal cartilage constructs, Invitrogen aggrecan antibody (Thermo Fisher, 969D4D11) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 3p). Tissue Eng Part C Methods (2016) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - frozen section; human; 1:500; loading ...; fig 2c
In order to test if TGF-beta supplementation stimulates chondrocyte redifferentiation, Invitrogen aggrecan antibody (ThermoFisher Scientific, AHP0022) was used in immunohistochemistry - frozen section on human samples at 1:500 (fig 2c). Tissue Eng Part A (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 3
In order to determine the effects of hydroxytyrosol and procyanidin treatment on osteoarthritis using rabbits, Invitrogen aggrecan antibody (Thermo Fisher Scientific, PA1-1746) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - paraffin section; rat; 1:100; fig 7
  • immunohistochemistry - paraffin section; pigs ; 1:100; fig 7
In order to utilize a decellularized cartilage-based hydrogel to help with the compressive modulus of articular cartilage, Invitrogen aggrecan antibody (ThermoFisher Scientific, MA3-16888) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 7) and in immunohistochemistry - paraffin section on pigs samples at 1:100 (fig 7). Acta Biomater (2016) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - frozen section; pigs ; 1:100; fig 8
In order to compare devitalized and decellularized cartilage encapsulated in hydrogel pastes as chondroinduction from naturally derived cartilage matrix, Invitrogen aggrecan antibody (ThermoFisher, MA3-16888) was used in immunohistochemistry - frozen section on pigs samples at 1:100 (fig 8). Tissue Eng Part A (2016) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - paraffin section; zebrafish ; fig 5
In order to analyze how Cx43-dependent skeletal phenotypes are mediated by interactions between Sema3d and HapIn1a-ECM during regeneration of fins, Invitrogen aggrecan antibody (Thermo Scientific, MA3-16888) was used in immunohistochemistry - paraffin section on zebrafish samples (fig 5). PLoS ONE (2016) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - frozen section; rat; 1:100; fig 9
  • immunohistochemistry - frozen section; pigs ; 1:100; fig 9
In order to research naturally derived devitalized cartilage used as chondroinductive hydrogel pastes, Invitrogen aggrecan antibody (ThermoFisher, MA3-16888) was used in immunohistochemistry - frozen section on rat samples at 1:100 (fig 9) and in immunohistochemistry - frozen section on pigs samples at 1:100 (fig 9). Ann Biomed Eng (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 2
In order to analyze development of experimental osteoarthritis and aggrecan degradation in murine articular cartilage by JNK-2, Invitrogen aggrecan antibody (Thermo Scientific, PA1-1746) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 2). Arthritis Rheumatol (2016) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - frozen section; zebrafish ; fig 1c
In order to analyze extracellular matrix protein expression during caudal fin regeneration in zebrafish, Invitrogen aggrecan antibody (Thermo Scientific, MA3-16888) was used in immunohistochemistry - frozen section on zebrafish samples (fig 1c). Gene Expr Patterns (2015) ncbi
mouse monoclonal (969D4D11)
  • blocking or activating experiments; human
In order to assess the therapeutic use of monoclonal antibodies to ADAMTS-5 and ADAMTS-4 in pathogenic cartilage degradation, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in blocking or activating experiments on human samples . Osteoarthritis Cartilage (2015) ncbi
mouse monoclonal (969D4D11)
  • immunocytochemistry; human
In order to discuss the role of inflammation in posttraumatic arthritis, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in immunocytochemistry on human samples . Am J Sports Med (2015) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - paraffin section; human; fig 9
In order to examine the ability of gamma-PGA to support production of cartilaginous extracellular matrix, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in immunohistochemistry - paraffin section on human samples (fig 9). Tissue Eng Part A (2015) ncbi
mouse monoclonal (969D4D11)
  • immunocytochemistry; human; 1:300
In order to examine the influence of gap junction-mediated cell-cell communication on chondrogenesis of bone marrow-derived mesenchymal stromal cells and articular chondrocytes, Invitrogen aggrecan antibody (Life Technologies, 969D4D11) was used in immunocytochemistry on human samples at 1:300. Tissue Eng Part A (2015) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - frozen section; human; 1:10000
Invitrogen aggrecan antibody (Biosource-C LuBioScience, AHP0022) was used in immunohistochemistry - frozen section on human samples at 1:10000. Eur Cell Mater (2015) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - frozen section; human; 1:300
In order to study the mechanical properties of tissue-engineered cartilage constructs using in vitro culture models incorporating human chondrocytes from osteoarthritis patients, Invitrogen aggrecan antibody (Invitrogen, 969D4D11) was used in immunohistochemistry - frozen section on human samples at 1:300. PLoS ONE (2014) ncbi
mouse monoclonal (969D4D11)
  • western blot; human; 1:500
In order to study the association between disc degeneration and autoimmunity, Invitrogen aggrecan antibody (Biosource, AHP0022) was used in western blot on human samples at 1:500. Eur Cell Mater (2014) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - paraffin section; human
In order to study how mesencymal stem cells in alginate hydrogels can form neocartilage in regards to biochemical and structural characterization, Invitrogen aggrecan antibody (BioSource, 969D4D11) was used in immunohistochemistry - paraffin section on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (969D4D11)
  • immunoprecipitation; human; fig 1
In order to evaludate a novel ARGS-aggrecan assay, Invitrogen aggrecan antibody (nvitrogen, AHP0022) was used in immunoprecipitation on human samples (fig 1). Osteoarthritis Cartilage (2014) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - frozen section; human; fig 5
In order to study the effect of testosterone on intervertebral disc, Invitrogen aggrecan antibody (Biosource, clone 969D4D11) was used in immunohistochemistry - frozen section on human samples (fig 5). Spine J (2014) ncbi
mouse monoclonal (969D4D11)
  • immunocytochemistry; human; 2.28 ug/ml; fig 2
In order to test if osteoarthritis chondrocytes are suitable for tissue engineering of articular cartilage., Invitrogen aggrecan antibody (BioSource, 969D4D11) was used in immunocytochemistry on human samples at 2.28 ug/ml (fig 2). PLoS ONE (2013) ncbi
mouse monoclonal (969D4D11)
  • ELISA; human; fig 1
In order to determine the concentrations of cartilage and bone markers, and pro-inflammatory cytokines in synovial fluid collected from acutely injured knees with hemarthrosis and healthy controls, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in ELISA on human samples (fig 1). Osteoarthritis Cartilage (2012) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - paraffin section; human; fig 1
In order to generate a three-dimensional cartilage scaffold and incorporate fetal cartilage rudiment cells, Invitrogen aggrecan antibody (Invitrogen, 969D4D11) was used in immunohistochemistry - paraffin section on human samples (fig 1). Biomaterials (2012) ncbi
mouse monoclonal (969D4D11)
  • ELISA; human; fig 3
In order to examine if changes in aggrecanase generated ARGS-aggrecan in synovial fluid is associated with progression of radiographic knee osteoarthritis and patient-reported outcome, Invitrogen aggrecan antibody (Invitrogen, clone AHP0022) was used in ELISA on human samples (fig 3). Osteoarthritis Cartilage (2012) ncbi
mouse monoclonal (969D4D11)
  • ELISA; human; fig 4
In order to determine the structure and function of the glycosaminoglycan chain of lubricin in human synovial fluid, Invitrogen aggrecan antibody (Invitrogen, 969D4D11) was used in ELISA on human samples (fig 4). Connect Tissue Res (2012) ncbi
mouse monoclonal (969D4D11)
  • western blot; human; 1:500; fig 2
In order to study the association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in western blot on human samples at 1:500 (fig 2). Arthritis Res Ther (2010) ncbi
mouse monoclonal (969D4D11)
  • ELISA; human; tbl 2
In order to assess changes after acute injury to the anterior cruciate ligament using synovial fluid and serum biomarkers, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in ELISA on human samples (tbl 2). Arthritis Res Ther (2010) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry; human; 1:20,000; fig 2
In order to determine the localization of type II collagen, aggrecan, and perlecan in young ovine joints, Invitrogen aggrecan antibody (Biosource Europe, (clone 969D4D11) was used in immunohistochemistry on human samples at 1:20,000 (fig 2). Histochem Cell Biol (2010) ncbi
mouse monoclonal (969D4D11)
  • ELISA; human; 1:8000; fig 6
In order to describe a method to detect aggrecanase-cleaved fragments of aggrecan in human serum and urine and use this assay to screen for inhibitors, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in ELISA on human samples at 1:8000 (fig 6). Osteoarthritis Cartilage (2010) ncbi
mouse monoclonal (969D4D11)
  • ELISA; human; fig 1
In order to develop an ELISA-based method to detect specific aggrecanase-cleaved aggrecan fragments in rats, Invitrogen aggrecan antibody (Invitrogen, AHP0022) was used in ELISA on human samples (fig 1). Osteoarthritis Cartilage (2010) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - paraffin section; domestic sheep; 1:20,000
In order to compare Histochoice and formalin fixation for cartilaginous tissues, Invitrogen aggrecan antibody (Biosource, 969D4D11) was used in immunohistochemistry - paraffin section on domestic sheep samples at 1:20,000. Biotech Histochem (2008) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - frozen section; human; 2 ug/ml; fig 9
In order to create scaffolds with silkworm cocoon, spider egg sac, and spider dragline silk fibers and examine their use for chondrocyte attachment and support, Invitrogen aggrecan antibody (Biosource, 969D4D11) was used in immunohistochemistry - frozen section on human samples at 2 ug/ml (fig 9). J Mater Sci Mater Med (2008) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry; human; fig 1
In order to study the localization and function of perlecan in human fetal, postnatal, and mature hyaline cartilages, Invitrogen aggrecan antibody (BIOSOURCE, 969D4D11) was used in immunohistochemistry on human samples (fig 1). J Biol Chem (2006) ncbi
mouse monoclonal (969D4D11)
  • immunohistochemistry - paraffin section; domestic sheep; 1:1000; fig 4
In order to study perlecan localization in the articular and epiphyseal growth plate cartilages of stifle joints in pedigree merino sheep, Invitrogen aggrecan antibody (Biosource, 969D4D11) was used in immunohistochemistry - paraffin section on domestic sheep samples at 1:1000 (fig 4). Histochem Cell Biol (2005) ncbi
mouse monoclonal (969D4D11)
  • flow cytometry; human
In order to examine the extracellular matrix of human meniscus cells cultured under different conditions, Invitrogen aggrecan antibody (Biosource, 969D4D11) was used in flow cytometry on human samples . Osteoarthritis Cartilage (2005) ncbi
mouse monoclonal (969D4D11)
  • immunocytochemistry; human
In order to describe methods to generate cartilage from human articular chondrocytes, Invitrogen aggrecan antibody (Biosource, 969D4D11) was used in immunocytochemistry on human samples . Ann Rheum Dis (2001) ncbi
Abcam
domestic rabbit monoclonal (EPR14664)
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1e
Abcam aggrecan antibody (Abcam, ab186414) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1e). Cells (2020) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 5j
Abcam aggrecan antibody (Abcam, ab3773) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 5j). JCI Insight (2020) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4b
Abcam aggrecan antibody (Abcam, ab3773) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 4b). Cell Death Dis (2018) ncbi
mouse monoclonal (BC-3)
  • western blot; human; loading ...; fig 3a
Abcam aggrecan antibody (Abcam, ab3773) was used in western blot on human samples (fig 3a). Int J Mol Sci (2016) ncbi
mouse monoclonal (BC-3)
  • immunocytochemistry; human; 1:200
Abcam aggrecan antibody (Abcam, ab3773) was used in immunocytochemistry on human samples at 1:200. Biomaterials (2015) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - frozen section; bovine; 1:250; fig 5
Abcam aggrecan antibody (Abcam, ab3773-1) was used in immunohistochemistry - frozen section on bovine samples at 1:250 (fig 5). Tissue Eng Part A (2015) ncbi
mouse monoclonal (BC-3)
  • western blot; human
In order to identify the intracellular signaling pathways by which IL-1 causes aggrecan degradation by human chondrocytes and investigate how aggrecanase activity is regulated in chondrocytes, Abcam aggrecan antibody (Abcam, ab3773) was used in western blot on human samples . Arthritis Rheumatol (2015) ncbi
mouse monoclonal (BC-3)
  • immunohistochemistry - paraffin section; human; 1:40
Abcam aggrecan antibody (Abcam, ab3773) was used in immunohistochemistry - paraffin section on human samples at 1:40. Arthritis Res Ther (2013) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; rat; 1:2000; loading ...; fig 1f
MilliporeSigma aggrecan antibody (Sigma-Aldrich, SAB4500662) was used in western blot on rat samples at 1:2000 (fig 1f). Front Mol Neurosci (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 1
MilliporeSigma aggrecan antibody (Sigma, SAB4500662) was used in western blot on rat samples (fig 1). Cell Stress Chaperones (2016) ncbi
Bio-Rad
mouse monoclonal (7D4)
  • immunocytochemistry; human; fig 3c
  • western blot; human; fig 3b
Bio-Rad aggrecan antibody (AbD Serotec, MCA1454G) was used in immunocytochemistry on human samples (fig 3c) and in western blot on human samples (fig 3b). Sci Rep (2016) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (12/21/1-C-6)
  • immunohistochemistry - frozen section; mouse; 1:100; fig 3a
Developmental Studies Hybridoma Bank aggrecan antibody (Developmental Studies Hybridoma Bank, 12/21/1-C-6) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 3a). Biol Open (2017) ncbi
Articles Reviewed
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  48. Melrose J, Smith S, Cake M, Read R, Whitelock J. Perlecan displays variable spatial and temporal immunolocalisation patterns in the articular and growth plate cartilages of the ovine stifle joint. Histochem Cell Biol. 2005;123:561-71 pubmed
  49. Verdonk P, Forsyth R, Wang J, Almqvist K, Verdonk R, Veys E, et al. Characterisation of human knee meniscus cell phenotype. Osteoarthritis Cartilage. 2005;13:548-60 pubmed
  50. Almqvist K, Wang L, Wang J, Baeten D, Cornelissen M, Verdonk R, et al. Culture of chondrocytes in alginate surrounded by fibrin gel: characteristics of the cells over a period of eight weeks. Ann Rheum Dis. 2001;60:781-90 pubmed