This is a Validated Antibody Database (VAD) review about human acetyl CoA synthetase, based on 6 published articles (read how Labome selects the articles), using acetyl CoA synthetase antibody in all methods. It is aimed to help Labome visitors find the most suited acetyl CoA synthetase antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
acetyl CoA synthetase synonym: ACAS2; ACECS; ACS; ACSA; dJ1161H23.1; acetyl-coenzyme A synthetase, cytoplasmic; acetate thiokinase; acetate-CoA ligase; acetyl-Coenzyme A synthetase 2 (ADP forming); acyl-activating enzyme; cytoplasmic acetyl-coenzyme A synthetase

Knockout validation
Abcam
rabbit polyclonal
  • western blot knockout validation; mouse; 1:500; fig 2
  • western blot; human; 1:500; fig 1
In order to study stress erythropoiesis regulated by an acetate switch, Abcam acetyl CoA synthetase antibody (Abcam, ab66038) was used in western blot knockout validation on mouse samples at 1:500 (fig 2) and in western blot on human samples at 1:500 (fig 1). Nat Med (2014) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; loading ...; fig 6c
Abcam acetyl CoA synthetase antibody (Abcam, ab66038) was used in western blot on mouse samples (fig 6c). Science (2019) ncbi
rabbit monoclonal (EPR8500)
  • immunohistochemistry; human; 1:50; fig 6e
  • western blot; human; fig 6a
Abcam acetyl CoA synthetase antibody (Abcam, ab133664) was used in immunohistochemistry on human samples at 1:50 (fig 6e) and in western blot on human samples (fig 6a). Nat Commun (2016) ncbi
rabbit monoclonal (EPR8500)
  • immunocytochemistry; human; 1:150
Abcam acetyl CoA synthetase antibody (Epitomics, #6516?C1) was used in immunocytochemistry on human samples at 1:150. J Cell Physiol (2015) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; 1:500; fig 2
  • western blot; human; 1:500; fig 1
In order to study stress erythropoiesis regulated by an acetate switch, Abcam acetyl CoA synthetase antibody (Abcam, ab66038) was used in western blot knockout validation on mouse samples at 1:500 (fig 2) and in western blot on human samples at 1:500 (fig 1). Nat Med (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; loading ...; fig 1a
Santa Cruz Biotechnology acetyl CoA synthetase antibody (SantaCruz, SC-398559) was used in western blot on human samples (fig 1a). Oncol Lett (2018) ncbi
Invitrogen
rabbit monoclonal (T.407.4)
  • western blot; mouse; loading ...; fig 1e
In order to investigate the involvement of acetyl-CoA synthetase in histone acetylation and hippocampal memory, Invitrogen acetyl CoA synthetase antibody (Thermo, MA5-145810) was used in western blot on mouse samples (fig 1e). Nature (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (D19C6)
  • ChIP-Seq; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 1e
In order to investigate the involvement of acetyl-CoA synthetase in histone acetylation and hippocampal memory, Cell Signaling Technology acetyl CoA synthetase antibody (Cell Signaling, 3658) was used in ChIP-Seq on mouse samples (fig 3a) and in western blot on mouse samples (fig 1e). Nature (2017) ncbi
rabbit monoclonal (D19C6)
  • immunohistochemistry - paraffin section; mouse
  • immunohistochemistry; mouse; 1:150; fig s3
In order to study stress erythropoiesis regulated by an acetate switch, Cell Signaling Technology acetyl CoA synthetase antibody (Cell Signaling Technology, 3658) was used in immunohistochemistry - paraffin section on mouse samples and in immunohistochemistry on mouse samples at 1:150 (fig s3). Nat Med (2014) ncbi
Articles Reviewed
  1. Vodnala S, Eil R, Kishton R, Sukumar M, Yamamoto T, Ha N, et al. T cell stemness and dysfunction in tumors are triggered by a common mechanism. Science. 2019;363: pubmed publisher
  2. Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, et al. Detachment from the primary site and suspension in ascites as the initial step in metabolic reprogramming and metastasis to the omentum in ovarian cancer. Oncol Lett. 2018;15:1357-1361 pubmed publisher
  3. Mews P, Donahue G, Drake A, Luczak V, Abel T, Berger S. Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature. 2017;546:381-386 pubmed publisher
  4. Gao X, Lin S, Ren F, Li J, Chen J, Yao C, et al. Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016;7:11960 pubmed publisher
  5. Long P, Tighe S, Driscoll H, Fortner K, Viapiano M, Jaworski D. Acetate supplementation as a means of inducing glioblastoma stem-like cell growth arrest. J Cell Physiol. 2015;230:1929-43 pubmed publisher
  6. Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed publisher