This is a Validated Antibody Database (VAD) review about human abl, based on 46 published articles (read how Labome selects the articles), using abl antibody in all methods. It is aimed to help Labome visitors find the most suited abl antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
abl synonym: ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl

Knockout validation
BD Biosciences
mouse monoclonal (8E9)
  • western blot knockout validation; mouse; loading ...; fig 5d
BD Biosciences abl antibody (BD, 554148) was used in western blot knockout validation on mouse samples (fig 5d). J Clin Invest (2016) ncbi
BD Biosciences
mouse monoclonal (8E9)
  • immunocytochemistry knockout validation; mouse; fig 1
In order to report a role for Abl PxxP motifs in the regulation of cell spreading, BD Biosciences abl antibody (BD Pharmingen, 8E9) was used in immunocytochemistry knockout validation on mouse samples (fig 1). J Cell Sci (2008) ncbi
Santa Cruz Biotechnology
mouse monoclonal (24-11)
  • immunoprecipitation; mouse; 1:50; loading ...; fig 6a
  • western blot; mouse; 1:100; loading ...; fig 6c
Santa Cruz Biotechnology abl antibody (Santa Cruz, sc-23) was used in immunoprecipitation on mouse samples at 1:50 (fig 6a) and in western blot on mouse samples at 1:100 (fig 6c). Nat Commun (2022) ncbi
mouse monoclonal (24-11)
  • western blot; mouse; loading ...; fig s2a
Santa Cruz Biotechnology abl antibody (Santa Cruz, 24-11) was used in western blot on mouse samples (fig s2a). Front Cell Dev Biol (2021) ncbi
mouse monoclonal (24-11)
  • western blot; human; loading ...; fig 4c
Santa Cruz Biotechnology abl antibody (Santa, 24-11) was used in western blot on human samples (fig 4c). Acta Neuropathol Commun (2020) ncbi
mouse monoclonal (24-11)
  • western blot; human; 1:1000; loading ...; fig 1s1a
Santa Cruz Biotechnology abl antibody (Santa, 23) was used in western blot on human samples at 1:1000 (fig 1s1a). elife (2019) ncbi
mouse monoclonal (24-11)
  • western blot; human; 1:500; loading ...; fig 5d
Santa Cruz Biotechnology abl antibody (Santa Cruz Biotech, sc-23) was used in western blot on human samples at 1:500 (fig 5d). Am J Respir Cell Mol Biol (2019) ncbi
mouse monoclonal (8E9)
  • immunoprecipitation; mouse; loading ...; fig 8e
  • western blot; mouse; loading ...; fig 8d
Santa Cruz Biotechnology abl antibody (Santa Cruz Biotechnology, sc-56887) was used in immunoprecipitation on mouse samples (fig 8e) and in western blot on mouse samples (fig 8d). J Clin Invest (2018) ncbi
mouse monoclonal (24-11)
  • western blot; human; fig 4
Santa Cruz Biotechnology abl antibody (Santa Cruz, sc-23) was used in western blot on human samples (fig 4). J Med Chem (2018) ncbi
mouse monoclonal (7.Tyr 412)
  • western blot; human; fig 4
Santa Cruz Biotechnology abl antibody (Santa Cruz, sc-293130) was used in western blot on human samples (fig 4). J Med Chem (2018) ncbi
mouse monoclonal (8E9)
  • western blot; mouse; loading ...; fig 5c
Santa Cruz Biotechnology abl antibody (Santa Cruz, sc-56887) was used in western blot on mouse samples (fig 5c). Bone (2018) ncbi
mouse monoclonal (7.Tyr 412)
  • western blot; mouse; fig 1
Santa Cruz Biotechnology abl antibody (santa Cruz, sc-293130) was used in western blot on mouse samples (fig 1). Leukemia (2016) ncbi
mouse monoclonal (8E9)
  • western blot; mouse; 1:1000; fig s1
Santa Cruz Biotechnology abl antibody (Santa Cruz, sc-56887) was used in western blot on mouse samples at 1:1000 (fig s1). Front Cell Neurosci (2015) ncbi
mouse monoclonal (24-11)
  • western blot; human; fig 1
Santa Cruz Biotechnology abl antibody (Santa Cruz, 23) was used in western blot on human samples (fig 1). Cell Signal (2015) ncbi
mouse monoclonal (24-11)
  • western blot; human
In order to study the effect of Imatinib on VASP activity and its interaction with Zyxin in BCR-ABL leukemic cells, Santa Cruz Biotechnology abl antibody (Santa Cruz Biotechnology, sc-23) was used in western blot on human samples . Biochim Biophys Acta (2015) ncbi
mouse monoclonal (24-11)
  • immunoprecipitation; rat
  • immunocytochemistry; rat
Santa Cruz Biotechnology abl antibody (Santa Cruz Biotechnology, sc-23) was used in immunoprecipitation on rat samples and in immunocytochemistry on rat samples . PLoS ONE (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:100; loading ...; fig 6j, 7a
Abcam abl antibody (Abcam, ab193223) was used in western blot on mouse samples at 1:100 (fig 6j, 7a). Nat Commun (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s11b
Abcam abl antibody (Abcam, ab4717) was used in western blot on mouse samples at 1:1000 (fig s11b). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
Abcam abl antibody (Abcam, ab15130) was used in western blot on mouse samples at 1:1000 (fig 5a). J Clin Invest (2019) ncbi
Invitrogen
mouse monoclonal (8E9)
  • immunocytochemistry; mouse
In order to investigate Abl nuclear import in DNA damage-induced apoptosis, Invitrogen abl antibody (Invitrogen, 8E9) was used in immunocytochemistry on mouse samples . Cell Death Differ (2007) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s1b
Cell Signaling Technology abl antibody (Cell Signaling, 2862) was used in western blot on human samples (fig s1b). Angiogenesis (2021) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology abl antibody (Cell Signaling, 2865) was used in western blot on mouse samples at 1:1000 (fig 4b). Aging Cell (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s11b
  • western blot; human; 1:1000; loading ...; fig 5f
Cell Signaling Technology abl antibody (Cell Signaling, 2862s) was used in western blot on mouse samples at 1:1000 (fig s11b) and in western blot on human samples at 1:1000 (fig 5f). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4k
Cell Signaling Technology abl antibody (Cell Signaling, 2862) was used in western blot on mouse samples (fig 4k). Sci Adv (2019) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; mouse; loading ...; fig s8d
Cell Signaling Technology abl antibody (Cell Signaling, 2865) was used in western blot on mouse samples (fig s8d). Blood (2018) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology abl antibody (Cell Signaling, 2862) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 2b
Cell Signaling Technology abl antibody (Cell Signaling, 2861) was used in western blot on mouse samples (fig 2b). Biochemistry (2018) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; mouse; fig 4c
Cell Signaling Technology abl antibody (Cell Signaling, 2865) was used in western blot on mouse samples (fig 4c). Nature (2017) ncbi
domestic rabbit monoclonal (73E5)
  • western blot; human; loading ...; fig s3c
  • western blot; mouse; fig s3b
Cell Signaling Technology abl antibody (Cell Signaling, 2868) was used in western blot on human samples (fig s3c) and in western blot on mouse samples (fig s3b). Leukemia (2017) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; human; loading ...; fig s3b
  • western blot; mouse; fig s3b
Cell Signaling Technology abl antibody (Cell Signaling, 2865) was used in western blot on human samples (fig s3b) and in western blot on mouse samples (fig s3b). Leukemia (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1f
In order to show that the Abl-DDB1-DDA1 axis reduces CRL4 substrate ubiquitination, Cell Signaling Technology abl antibody (Cell Signaling, 2861S) was used in western blot on human samples (fig 1f). J Biol Chem (2017) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology abl antibody (Cell Signaling, 2862) was used in immunoprecipitation on human samples (fig 2a) and in western blot on human samples (fig 2a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (73E5)
  • immunocytochemistry; human; loading ...; fig 5
Cell Signaling Technology abl antibody (Cell Signaling, 2868) was used in immunocytochemistry on human samples (fig 5). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology abl antibody (Cell Signaling, 2862) was used in western blot on human samples (fig 1b). Int J Nanomedicine (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4c
  • western blot; mouse; fig 1f
Cell Signaling Technology abl antibody (cell signalling, 2861) was used in western blot on human samples (fig 4c) and in western blot on mouse samples (fig 1f). J Clin Invest (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology abl antibody (Signaling Technology, 2862) was used in western blot on human samples (fig 5). J Cell Mol Med (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1g
  • western blot; mouse; loading ...; fig 1a, 1c
Cell Signaling Technology abl antibody (Cell signaling, 2861) was used in immunohistochemistry on mouse samples (fig 1g) and in western blot on mouse samples (fig 1a, 1c). J Clin Invest (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:3000; fig 8
In order to study kinase DYRK1A selective inhibition by targeting its folding process, Cell Signaling Technology abl antibody (Cell Signaling Technology, 2862BC) was used in western blot on human samples at 1:3000 (fig 8). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology abl antibody (Cell Signaling, 2861) was used in western blot on human samples at 1:1000 (fig 3a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology abl antibody (Cell Signaling, 2862) was used in western blot on mouse samples (fig 1a). Cell Death Differ (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology abl antibody (Cell Signaling, 2861) was used in western blot on mouse samples (fig 1a). Cell Death Differ (2016) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; human; fig 1a
Cell Signaling Technology abl antibody (Cell Signaling, 2865) was used in western blot on human samples (fig 1a). Leukemia (2015) ncbi
domestic rabbit polyclonal
  • ELISA; human
In order to investigate the role of Tyr245 phosphorylation in Abelson kinase function, Cell Signaling Technology abl antibody (Cell Signaling Technology, 2861) was used in ELISA on human samples . Eur J Haematol (2016) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology abl antibody (Cell Signaling, 2865) was used in western blot on human samples (fig 3c). Cell Commun Signal (2015) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology abl antibody (Cell signaling, 2865) was used in western blot on human samples (fig 4b). Int J Cancer (2015) ncbi
  • western blot; human; loading ...; fig 4b
In order to investigate the role of GNB1 and GNB2 in cancer cells., Cell Signaling Technology abl antibody (Cell signaling, 5300) was used in western blot on human samples (fig 4b). Nat Med (2015) ncbi
domestic rabbit monoclonal (73E5)
  • western blot; human; 1:500-1:1000
In order to study the effect of imatinib on neuroblastoma cell lines, Cell Signaling Technology abl antibody (Cell Signaling, 2868) was used in western blot on human samples at 1:500-1:1000. Biochem Pharmacol (2014) ncbi
domestic rabbit monoclonal (247C7)
  • western blot; human; 1:1000
Cell Signaling Technology abl antibody (Cell Signaling, 2865) was used in western blot on human samples at 1:1000. Oncogene (2013) ncbi
BD Biosciences
mouse monoclonal (8E9)
  • immunoprecipitation; human; loading ...; fig 7b
  • western blot; human; loading ...; fig 4f
  • immunocytochemistry; mouse; fig 3a
  • western blot; mouse; fig 2i
BD Biosciences abl antibody (BD Pharmingen, 554148) was used in immunoprecipitation on human samples (fig 7b), in western blot on human samples (fig 4f), in immunocytochemistry on mouse samples (fig 3a) and in western blot on mouse samples (fig 2i). J Clin Invest (2016) ncbi
mouse monoclonal (8E9)
  • western blot knockout validation; mouse; loading ...; fig 5d
BD Biosciences abl antibody (BD, 554148) was used in western blot knockout validation on mouse samples (fig 5d). J Clin Invest (2016) ncbi
mouse monoclonal (8E9)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences abl antibody (BD, 8e9) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (8E9)
  • immunocytochemistry; human; loading ...; fig 5a
  • western blot; human; loading ...; fig 1a
BD Biosciences abl antibody (BD Pharmingen, 554148) was used in immunocytochemistry on human samples (fig 5a) and in western blot on human samples (fig 1a). Autophagy (2015) ncbi
mouse monoclonal (8E9)
  • western blot; human; fig 1
BD Biosciences abl antibody (BD Pharmingen, 8E9) was used in western blot on human samples (fig 1). J Biol Chem (2013) ncbi
mouse monoclonal (8E9)
  • immunocytochemistry knockout validation; mouse; fig 1
In order to report a role for Abl PxxP motifs in the regulation of cell spreading, BD Biosciences abl antibody (BD Pharmingen, 8E9) was used in immunocytochemistry knockout validation on mouse samples (fig 1). J Cell Sci (2008) ncbi
mouse monoclonal (8E9)
  • immunoprecipitation; human
  • western blot; human
In order to study the interactions between Vav and Bcr-Abl, BD Biosciences abl antibody (BD PharMingen, 8E9) was used in immunoprecipitation on human samples and in western blot on human samples . J Biol Chem (2002) ncbi
MilliporeSigma
mouse monoclonal (ABL-148)
  • ELISA; human
In order to investigate the role of Tyr245 phosphorylation in Abelson kinase function, MilliporeSigma abl antibody (Sigma-Aldrich, A5844) was used in ELISA on human samples . Eur J Haematol (2016) ncbi
Articles Reviewed
  1. Mohamed M, Gupta K, Goldufsky J, Roy R, Callaghan L, Wetzel D, et al. CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT. Nat Commun. 2022;13:1295 pubmed publisher
  2. Yuan B, Yang J, Dubeau L, Hu Y, Li R. A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function. Front Cell Dev Biol. 2021;9:649087 pubmed publisher
  3. Amado Azevedo J, van Stalborch A, Valent E, Nawaz K, van Bezu J, Eringa E, et al. Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation. Angiogenesis. 2021;: pubmed publisher
  4. Wallace M, Aguirre N, Marcotte G, Marshall A, Baehr L, Hughes D, et al. The ketogenic diet preserves skeletal muscle with aging in mice. Aging Cell. 2021;20:e13322 pubmed publisher
  5. Zhou H, Qin L, Jiang Q, Murray K, Zhang H, Li B, et al. Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model. Nat Commun. 2021;12:504 pubmed publisher
  6. Kim B, Jeong Y, Wong M, Martin L. DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations. Acta Neuropathol Commun. 2020;8:7 pubmed publisher
  7. Zhao X, Xie H, Zhao M, Ahsan A, Li X, Wang F, et al. Fc receptor-like 1 intrinsically recruits c-Abl to enhance B cell activation and function. Sci Adv. 2019;5:eaaw0315 pubmed publisher
  8. Langer L, Ward J, Archer T. Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination. elife. 2019;8: pubmed publisher
  9. Gerlach B, Tubbesing K, Liao G, Rezey A, Wang R, Barroso M, et al. Phosphorylation of GMFγ by c-Abl Coordinates Lamellipodial and Focal Adhesion Dynamics to Regulate Airway Smooth Muscle Cell Migration. Am J Respir Cell Mol Biol. 2019;: pubmed publisher
  10. Li B, He J, Lv H, Liu Y, Lv X, Zhang C, et al. c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. J Clin Invest. 2019;129:1167-1179 pubmed publisher
  11. Li C, Xiao Y, Yang M, Su T, Sun X, Guo Q, et al. Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. J Clin Invest. 2018;128:5251-5266 pubmed publisher
  12. Chorzalska A, Morgan J, Ahsan N, Treaba D, Olszewski A, Petersen M, et al. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018;: pubmed publisher
  13. Wang Z, Zhang Y, Pinkas D, Fox A, Luo J, Huang H, et al. Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2. J Med Chem. 2018;: pubmed publisher
  14. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  15. Wang Z, Kim M, Martinez Ferrando I, Koleske A, Pandey A, Cole P. Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase. Biochemistry. 2018;57:1390-1398 pubmed publisher
  16. Fujita S, Mukai T, Mito T, Kodama S, Nagasu A, Kittaka M, et al. Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis. Bone. 2018;106:156-166 pubmed publisher
  17. Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher
  18. Reckel S, Hamelin R, Georgeon S, Armand F, Jolliet Q, Chiappe D, et al. Differential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics. Leukemia. 2017;31:1502-1512 pubmed publisher
  19. Gao S, Geng C, Song T, Lin X, Liu J, Cai Z, et al. Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase. J Biol Chem. 2017;292:3683-3691 pubmed publisher
  20. Chen C, Zhuang Y, Chen X, Chen X, Li D, Fan Y, et al. Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells. Oncotarget. 2017;8:10025-10036 pubmed publisher
  21. Assadi G, Vesterlund L, Bonfiglio F, Mazzurana L, Cordeddu L, Schepis D, et al. Functional Analyses of the Crohn's Disease Risk Gene LACC1. PLoS ONE. 2016;11:e0168276 pubmed publisher
  22. Shi D, Liu Y, Xi R, Zou W, Wu L, Zhang Z, et al. Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells. Int J Nanomedicine. 2016;11:5823-5835 pubmed
  23. Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
  24. Ah Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed publisher
  25. Brahmachari S, Ge P, Lee S, Kim D, Karuppagounder S, Kumar M, et al. Activation of tyrosine kinase c-Abl contributes to ?-synuclein-induced neurodegeneration. J Clin Invest. 2016;126:2970-88 pubmed publisher
  26. Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher
  27. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  28. Zabriskie M, Eide C, Yan D, Vellore N, Pomicter A, Savage S, et al. Extreme mutational selectivity of axitinib limits its potential use as a targeted therapeutic for BCR-ABL1-positive leukemia. Leukemia. 2016;30:1418-21 pubmed publisher
  29. Ko T, Chin H, Chuah C, Huang J, Ng K, Khaw S, et al. The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia. Oncotarget. 2016;7:2721-33 pubmed publisher
  30. Wu R, Chen H, Ma J, He Q, Huang Q, Liu Q, et al. c-Abl-p38α signaling plays an important role in MPTP-induced neuronal death. Cell Death Differ. 2016;23:542-52 pubmed publisher
  31. Colecchia D, Rossi M, Sasdelli F, Sanzone S, Strambi A, Chiariello M. MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation. Autophagy. 2015;11:1790-802 pubmed publisher
  32. Eiring A, Khorashad J, Anderson D, Yu F, Redwine H, Mason C, et al. β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia. Leukemia. 2015;29:2328-37 pubmed publisher
  33. Skora L, Kempf D, Mestan J, D Orazio D, Jahnke W. Phosphorylation of Tyr245 in the open-inhibited state of Abelson kinase does not induce downstream signaling. Eur J Haematol. 2016;96:502-6 pubmed publisher
  34. Rojas F, Gonzalez D, Cortes N, Ampuero E, Hernández D, Fritz E, et al. Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Front Cell Neurosci. 2015;9:203 pubmed publisher
  35. Fahrenkamp D, de Leur H, Küster A, Chatain N, Müller Newen G. Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction. Cell Commun Signal. 2015;13:10 pubmed publisher
  36. Bilal M, Zhang E, Dinkel B, Hardy D, Yankee T, Houtman J. GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells. Cell Signal. 2015;27:841-50 pubmed publisher
  37. Nasr R, Hmadi R, El Eit R, Iskandarani A, Jabbour M, Zaatari G, et al. ST1926, an orally active synthetic retinoid, induces apoptosis in chronic myeloid leukemia cells and prolongs survival in a murine model. Int J Cancer. 2015;137:698-709 pubmed publisher
  38. Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, et al. Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. Nat Med. 2015;21:71-5 pubmed publisher
  39. Bernusso V, Machado Neto J, Pericole F, Vieira K, Duarte A, Traina F, et al. Imatinib restores VASP activity and its interaction with Zyxin in BCR-ABL leukemic cells. Biochim Biophys Acta. 2015;1853:388-95 pubmed publisher
  40. Lupino E, Ramondetti C, Buccinnà B, Piccinini M. Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27(KIP1) as a consequence of c-Abl inhibition. Biochem Pharmacol. 2014;92:235-50 pubmed publisher
  41. Vargas L, Leal N, Estrada L, González A, Serrano F, Araya K, et al. EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers. PLoS ONE. 2014;9:e92309 pubmed publisher
  42. Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, et al. Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1? (HP1?) with heterochromatin. J Biol Chem. 2013;288:17871-83 pubmed publisher
  43. Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed publisher
  44. Antoku S, Saksela K, Rivera G, Mayer B. A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors. J Cell Sci. 2008;121:3071-82 pubmed publisher
  45. Preyer M, Shu C, Wang J. Delayed activation of Bax by DNA damage in embryonic stem cells with knock-in mutations of the Abl nuclear localization signals. Cell Death Differ. 2007;14:1139-48 pubmed
  46. Bassermann F, Jahn T, Miething C, Seipel P, Bai R, Coutinho S, et al. Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway. J Biol Chem. 2002;277:12437-45 pubmed