This is a Validated Antibody Database (VAD) review about human YES1, based on 31 published articles (read how Labome selects the articles), using YES1 antibody in all methods. It is aimed to help Labome visitors find the most suited YES1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
YES1 synonym: HsT441; P61-YES; Yes; c-yes; tyrosine-protein kinase Yes; YES1 proto-oncogene, Src family tyrosine kinase; Yamaguchi sarcoma oncogene; cellular yes-1 protein; proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

Santa Cruz Biotechnology
mouse monoclonal (F-7)
  • western blot; human; loading ...; fig 3c
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, SC-8403) was used in western blot on human samples (fig 3c). Redox Biol (2017) ncbi
mouse monoclonal (B-12)
  • western blot; human; 1:1000; loading ...; fig s9b
In order to examine whether p140Cap protein levels in ERBB2-amplified breast cancer patients correlate with survival, Santa Cruz Biotechnology YES1 antibody (Santa Cruz, B-12) was used in western blot on human samples at 1:1000 (fig s9b). Nat Commun (2017) ncbi
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig s9b
In order to examine whether p140Cap protein levels in ERBB2-amplified breast cancer patients correlate with survival, Santa Cruz Biotechnology YES1 antibody (Santa Cruz, B-12) was used in western blot on human samples at 1:1000 (fig s9b). Nat Commun (2017) ncbi
mouse monoclonal (B-12)
  • western blot; rat; loading ...
In order to examine the impact of ischemia/reperfusion injury on sodium potassium ATPase enzymatic and signaling functions, Santa Cruz Biotechnology YES1 antibody (Santa Cruz, Sc-8056) was used in western blot on rat samples . Physiol Rep (2016) ncbi
mouse monoclonal (F-7)
  • western blot; human; loading ...; fig 4c
In order to characterize the molecular changes involved in human aortic smooth muscle cell proliferation, Santa Cruz Biotechnology YES1 antibody (Santa Cruz Biotechnology, SC-8403) was used in western blot on human samples (fig 4c). Sci Rep (2016) ncbi
mouse monoclonal (B-12)
  • western blot; human; fig 2
In order to determine an enrichment in insulin-like growth factor I receptor, c-Src, G-protein-coupled receptor kinases, and focal adhesion kinase in porstate cancer cell exosomes, Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc8056) was used in western blot on human samples (fig 2). J Cell Biochem (2017) ncbi
mouse monoclonal (B-12)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
  • immunoprecipitation; human; 1:50; fig 4
  • immunocytochemistry; human; 1:100; fig 4
  • western blot; human; 1:200; fig 1
In order to study improvement of the pathology of hypertrophic scar by simultaneous deactivation of FAK and Src, Santa Cruz Biotechnology YES1 antibody (Santa Cruz Biotechnology, sc-8056) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1), in immunoprecipitation on human samples at 1:50 (fig 4), in immunocytochemistry on human samples at 1:100 (fig 4) and in western blot on human samples at 1:200 (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (F-7)
  • western blot; human; loading ...; fig 3e
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, 8403) was used in western blot on human samples (fig 3e). Nat Commun (2016) ncbi
mouse monoclonal (B-12)
  • western blot; human; 1:200; fig 1
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc-8056;) was used in western blot on human samples at 1:200 (fig 1). Int J Mol Med (2016) ncbi
mouse monoclonal (F-7)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology YES1 antibody (SCBT, F-7) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (B-12)
  • western blot; rat; loading ...; fig 8a
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc8056) was used in western blot on rat samples (fig 8a). J Cell Mol Med (2016) ncbi
mouse monoclonal (F-7)
  • western blot; human; fig 1,3,5
In order to research pancreatic epithelial cells and a possible sensor system through the hippo pathway co-localizing with occludin, Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc-8403) was used in western blot on human samples (fig 1,3,5). Tissue Barriers (2015) ncbi
mouse monoclonal (B-12)
  • immunocytochemistry; mouse
In order to investigate the molecular mechanisms involved in TASK1 internalization in PC12 cells, Santa Cruz Biotechnology YES1 antibody (Santa Cruz Biotechnology, sc-8056) was used in immunocytochemistry on mouse samples . Am J Physiol Cell Physiol (2015) ncbi
mouse monoclonal (B-12)
  • western blot; human
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc-8056) was used in western blot on human samples . Mol Cell Endocrinol (2015) ncbi
mouse monoclonal (B-12)
  • western blot; human; 1:1000; fig 5
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc-8056 B-12) was used in western blot on human samples at 1:1000 (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (B-12)
  • immunohistochemistry - paraffin section; human; 1:50
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc8056) was used in immunohistochemistry - paraffin section on human samples at 1:50. Exp Dermatol (2015) ncbi
mouse monoclonal (B-12)
  • immunocytochemistry; human; 1:50
  • western blot; human; 1:200
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, Sc-8056) was used in immunocytochemistry on human samples at 1:50 and in western blot on human samples at 1:200. Cell Signal (2015) ncbi
mouse monoclonal (B-12)
  • western blot; mouse; fig 8
Santa Cruz Biotechnology YES1 antibody (Santa Cruz Biotechnology, sc-8056) was used in western blot on mouse samples (fig 8). J Neurosci (2015) ncbi
mouse monoclonal (B-12)
  • western blot; pig
In order to study the effect of ouabain on Src kinase and Na(+)/K(+)-ATPase, Santa Cruz Biotechnology YES1 antibody (Santa Cruz Biotechnology, sc-8056) was used in western blot on pig samples . Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (B-12)
  • immunohistochemistry - paraffin section; human; 1:150
  • immunoprecipitation; human
  • western blot; human; 1:1000
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc-8056) was used in immunohistochemistry - paraffin section on human samples at 1:150, in immunoprecipitation on human samples and in western blot on human samples at 1:1000. Int J Cancer (2014) ncbi
mouse monoclonal (B-12)
  • western blot; human
Santa Cruz Biotechnology YES1 antibody (Santa Cruz Biotechnology, sc-8056) was used in western blot on human samples . Eur J Cancer (2014) ncbi
mouse monoclonal (B-12)
  • western blot; mouse
Santa Cruz Biotechnology YES1 antibody (Santa Cruz, sc-8056) was used in western blot on mouse samples . J Hepatol (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology YES1 antibody (Cell Signaling Technology, 3201) was used in western blot on human samples (fig 1b). Proc Natl Acad Sci U S A (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...
In order to target Src family kinase Src-homology 2 domains with high selectivity via the development of synthetic binding proteins, termed monobodies, Cell Signaling Technology YES1 antibody (Cell Signaling, 3201) was used in western blot on human samples . J Mol Biol (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology YES1 antibody (Cell Signaling, 3201) was used in western blot on human samples (fig 3e). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; 0.02 ug/ml; fig 4
In order to analyze breast cancer liver metastasis and how Lyn modulates Claudin-2 expression as a therapeutic target, Cell Signaling Technology YES1 antibody (Cell Signaling Technology, 3201) was used in western blot on human samples at 0.02 ug/ml (fig 4). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to study how phosphorylation alters COP1-binding sites of oncoproteins, Cell Signaling Technology YES1 antibody (Cell Signaling, 3201) was used in western blot on human samples . Cancer Cell (2014) ncbi
rabbit polyclonal
  • western blot; hamsters; fig 5
In order to determine the localization of host proteins within vesicular stomatitis virus virions, Cell Signaling Technology YES1 antibody (Cell Signaling, 3201) was used in western blot on hamsters samples (fig 5). PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the regulation of adipogenesis by mechanical strain in mesenchymal stem cells and the roles played by Fyn, mTORC2 and RhoA, Cell Signaling Technology YES1 antibody (Cell Signaling, 3201) was used in western blot on mouse samples . Stem Cells (2013) ncbi
BD Biosciences
mouse monoclonal (1/Yes)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences YES1 antibody (BD, 1) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (1/Yes)
  • western blot; human; fig 7
BD Biosciences YES1 antibody (BD, 610375) was used in western blot on human samples (fig 7). J Biol Chem (2014) ncbi
mouse monoclonal (1/Yes)
  • western blot; human
In order to study the role of C-terminal COOH of integrin beta1 in its association with kindlin-2 adapter protein, BD Biosciences YES1 antibody (BD Transduction Laboratories, 610375) was used in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (1/Yes)
  • immunoprecipitation; mouse
In order to test if c-Src and c-Yes act in biological opposition using embryonic stem cells, BD Biosciences YES1 antibody (BD, BD610375) was used in immunoprecipitation on mouse samples . ACS Chem Biol (2014) ncbi
Articles Reviewed
  1. Fan P, Narzisi G, Jayaprakash A, Venturini E, Robine N, Smibert P, et al. YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. Proc Natl Acad Sci U S A. 2018;115:E6030-E6038 pubmed publisher
  2. Kükenshöner T, Schmit N, Bouda E, Sha F, Pojer F, Koide A, et al. Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J Mol Biol. 2017;429:1364-1380 pubmed publisher
  3. Chattopadhyay R, Raghavan S, Rao G. Resolvin D1 via prevention of ROS-mediated SHP2 inactivation protects endothelial adherens junction integrity and barrier function. Redox Biol. 2017;12:438-455 pubmed publisher
  4. Merhi A, Delree P, Marini A. The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling. Sci Rep. 2017;7:44602 pubmed publisher
  5. Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, et al. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries. Nat Commun. 2017;8:14797 pubmed publisher
  6. Belliard A, Gulati G, Duan Q, Alves R, Brewer S, Madan N, et al. Ischemia/reperfusion-induced alterations of enzymatic and signaling functions of the rat cardiac Na+/K+-ATPase: protection by ouabain preconditioning. Physiol Rep. 2016;4: pubmed
  7. Janjanam J, Rao G. Novel role of cortactin in G protein-coupled receptor agonist-induced nuclear export and degradation of p21Cip1. Sci Rep. 2016;6:28687 pubmed publisher
  8. DeRita R, Zerlanko B, Singh A, Lu H, Iozzo R, Benovic J, et al. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes. J Cell Biochem. 2017;118:66-73 pubmed publisher
  9. Su L, Li X, Wu X, Hui B, Han S, Gao J, et al. Simultaneous deactivation of FAK and Src improves the pathology of hypertrophic scar. Sci Rep. 2016;6:26023 pubmed publisher
  10. Sprowl J, Ong S, Gibson A, Hu S, Du G, Lin W, et al. A phosphotyrosine switch regulates organic cation transporters. Nat Commun. 2016;7:10880 pubmed publisher
  11. Wu X, Yang L, Zheng Z, Li Z, Shi J, Li Y, et al. Src promotes cutaneous wound healing by regulating MMP-2 through the ERK pathway. Int J Mol Med. 2016;37:639-48 pubmed publisher
  12. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  13. Peng K, Tian X, Qian Y, Skibba M, Zou C, Liu Z, et al. Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II. J Cell Mol Med. 2016;20:482-94 pubmed publisher
  14. Cravo A, Carter E, Erkan M, Harvey E, Furutani Seiki M, MRSNY R. Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells. Tissue Barriers. 2015;3:e1037948 pubmed publisher
  15. Matsuoka H, Inoue M. Src mediates endocytosis of TWIK-related acid-sensitive K+ 1 channels in PC12 cells in response to nerve growth factor. Am J Physiol Cell Physiol. 2015;309:C251-63 pubmed publisher
  16. Chien P, Lin C, Hsiao L, Yang C. c-Src/Pyk2/EGFR/PI3K/Akt/CREB-activated pathway contributes to human cardiomyocyte hypertrophy: Role of COX-2 induction. Mol Cell Endocrinol. 2015;409:59-72 pubmed publisher
  17. Tabariès S, Annis M, Hsu B, Tam C, Savage P, Park M, et al. Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis. Oncotarget. 2015;6:9476-87 pubmed
  18. Carnesecchi J, Malbouyres M, de Mets R, Balland M, Beauchef G, Vié K, et al. Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30. PLoS ONE. 2015;10:e0120672 pubmed publisher
  19. Choi C, Kim Y, Sohn J, Lee H, Kim W. Focal adhesion kinase and Src expression in premalignant and malignant skin lesions. Exp Dermatol. 2015;24:361-4 pubmed publisher
  20. Tamilzhalagan S, Muthuswami M, Periasamy J, Lee M, Rha S, Tan P, et al. Upregulated, 7q21-22 amplicon candidate gene SHFM1 confers oncogenic advantage by suppressing p53 function in gastric cancer. Cell Signal. 2015;27:1075-86 pubmed publisher
  21. Sheng L, Leshchyns ka I, Sytnyk V. Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levels. J Neurosci. 2015;35:1739-52 pubmed publisher
  22. Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
  23. Moerdyk Schauwecker M, Hwang S, Grdzelishvili V. Cellular proteins associated with the interior and exterior of vesicular stomatitis virus virions. PLoS ONE. 2014;9:e104688 pubmed publisher
  24. Gable M, Abdallah S, Najjar S, Liu L, Askari A. Digitalis-induced cell signaling by the sodium pump: on the relation of Src to Na(+)/K(+)-ATPase. Biochem Biophys Res Commun. 2014;446:1151-4 pubmed publisher
  25. Fukumoto Y, Morii M, Miura T, Kubota S, Ishibashi K, Honda T, et al. Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint. J Biol Chem. 2014;289:12313-29 pubmed publisher
  26. Bouchekioua Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, et al. LKB1 when associated with methylatedER? is a marker of bad prognosis in breast cancer. Int J Cancer. 2014;135:1307-18 pubmed publisher
  27. Fitzpatrick P, Shattil S, Ablooglu A. C-terminal COOH of integrin ?1 is necessary for ?1 association with the kindlin-2 adapter protein. J Biol Chem. 2014;289:11183-93 pubmed publisher
  28. Cao M, Hou D, Liang H, Gong F, Wang Y, Yan X, et al. miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1. Eur J Cancer. 2014;50:1013-24 pubmed publisher
  29. Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-?B. J Hepatol. 2014;60:306-12 pubmed publisher
  30. Zhang X, Meyn M, Smithgall T. c-Yes tyrosine kinase is a potent suppressor of ES cell differentiation and antagonizes the actions of its closest phylogenetic relative, c-Src. ACS Chem Biol. 2014;9:139-46 pubmed publisher
  31. Thompson W, Guilluy C, Xie Z, Sen B, Brobst K, Yen S, et al. Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells. Stem Cells. 2013;31:2528-37 pubmed publisher