This is a Validated Antibody Database (VAD) review about human XRCC4, based on 5 published articles (read how Labome selects the articles), using XRCC4 antibody in all methods. It is aimed to help Labome visitors find the most suited XRCC4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
XRCC4 synonym: SSMED; DNA repair protein XRCC4; X-ray repair complementing defective repair in Chinese hamster cells 4

Santa Cruz Biotechnology
mouse monoclonal (G-10)
  • western blot; mouse
Santa Cruz Biotechnology XRCC4 antibody (Santa Cruz Biotechnology, sc-365118) was used in western blot on mouse samples . Biochim Biophys Acta (2015) ncbi
BD Biosciences
mouse monoclonal (4/XRCC4)
  • western blot; human; loading ...; fig 3a
In order to report the proteome of CADA-treated SUP-T1 human CD4+ T lymphocytes, BD Biosciences XRCC4 antibody (BD Biosciences, 4) was used in western blot on human samples (fig 3a). Mol Cell Proteomics (2017) ncbi
mouse monoclonal (4/XRCC4)
  • western blot; human; fig 3a
BD Biosciences XRCC4 antibody (BD, 611506) was used in western blot on human samples (fig 3a). PLoS Genet (2014) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Sigma-Aldrich XRCC4 antibody (SIGMA, HPA006801) was used in western blot on human samples (fig 4a). Sci Rep (2016) ncbi
rabbit polyclonal
  • other; human; fig 1, 2
  • western blot; human
In order to discuss methods to study nonhomologous end-joining repair proteins at double stranded DNA breaks, Sigma-Aldrich XRCC4 antibody (Sigma-Aldrich, HPA006801) was used in other on human samples (fig 1, 2) and in western blot on human samples . Proc Natl Acad Sci U S A (2015) ncbi
Articles Reviewed
  1. Van Puyenbroeck V, Claeys E, Schols D, Bell T, Vermeire K. A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA). Mol Cell Proteomics. 2017;16:157-167 pubmed publisher
  2. Bezine E, Malaisé Y, Loeuillet A, Chevalier M, Boutet Robinet E, Salles B, et al. Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms. Sci Rep. 2016;6:36022 pubmed publisher
  3. Reid D, Keegan S, Leo Macias A, Watanabe G, Strande N, Chang H, et al. Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair. Proc Natl Acad Sci U S A. 2015;112:E2575-84 pubmed publisher
  4. Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
  5. Terasawa M, Shinohara A, Shinohara M. Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4. PLoS Genet. 2014;10:e1004563 pubmed publisher