This is a Validated Antibody Database (VAD) review about human XPO1, based on 18 published articles (read how Labome selects the articles), using XPO1 antibody in all methods. It is aimed to help Labome visitors find the most suited XPO1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
XPO1 synonym: CRM-1; CRM1; emb; exp1

Santa Cruz Biotechnology
mouse monoclonal (C-1)
  • immunocytochemistry; human; fig 3f
Santa Cruz Biotechnology XPO1 antibody (Santa Cruz Technologies, sc-74454) was used in immunocytochemistry on human samples (fig 3f). Circulation (2021) ncbi
mouse monoclonal (C-1)
  • western blot; human; loading ...; fig 3h
Santa Cruz Biotechnology XPO1 antibody (Santa Cruz, sc-74454) was used in western blot on human samples (fig 3h). Science (2020) ncbi
mouse monoclonal (H-7)
  • immunocytochemistry; human; 1:200; loading ...; fig s5a
In order to describe the mechanism by which FBXW7 stabilizes RigI, Santa Cruz Biotechnology XPO1 antibody (Santa Cruz, sc-74455) was used in immunocytochemistry on human samples at 1:200 (fig s5a). Nat Commun (2017) ncbi
mouse monoclonal (C-1)
  • western blot; human; fig 9
In order to determine how cytosolic phospholipase A2alpha prohibits prostate cancer cells from re-entering the cell cyle, Santa Cruz Biotechnology XPO1 antibody (Santa Cruz Biotechnology, sc-74454) was used in western blot on human samples (fig 9). Oncotarget (2015) ncbi
mouse monoclonal (C-1)
  • western blot; human; fig 4
In order to use a combination of proteomics and functional genomics to identify novel HCV-host interactions, Santa Cruz Biotechnology XPO1 antibody (Santa, sc-74454) was used in western blot on human samples (fig 4). Mol Cell Proteomics (2014) ncbi
mouse monoclonal (C-1)
  • blocking or activating experiments; mouse
Santa Cruz Biotechnology XPO1 antibody (Santa Cruz Biotechnology, sc-74454) was used in blocking or activating experiments on mouse samples . Nucleic Acids Res (2012) ncbi
Abcam
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 3c
Abcam XPO1 antibody (Abcam, ab24189) was used in immunocytochemistry on human samples (fig 3c). J Virol (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D6V7N)
  • western blot; mouse; 1:2000; fig 4d
Cell Signaling Technology XPO1 antibody (Cell Signaling, 46249) was used in western blot on mouse samples at 1:2000 (fig 4d). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D6V7N)
  • immunohistochemistry - paraffin section; human; 1:400; fig 4e
  • western blot; human; fig 2k, 3c
Cell Signaling Technology XPO1 antibody (CST, 46249) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 4e) and in western blot on human samples (fig 2k, 3c). Oncogene (2021) ncbi
domestic rabbit monoclonal (D6V7N)
  • ChIP-Seq; human; loading ...; fig 1s1
Cell Signaling Technology XPO1 antibody (Cell Signaling, 46249) was used in ChIP-Seq on human samples (fig 1s1). elife (2019) ncbi
domestic rabbit monoclonal (D6V7N)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology XPO1 antibody (Cell Signaling, 46249) was used in western blot on human samples (fig 3a). EMBO J (2019) ncbi
BD Biosciences
mouse monoclonal (17/Exportin-1/CRM1)
  • immunohistochemistry; mouse; loading ...; fig s8f
BD Biosciences XPO1 antibody (BD, 611832) was used in immunohistochemistry on mouse samples (fig s8f). Nat Neurosci (2021) ncbi
mouse monoclonal (17/Exportin-1/CRM1)
  • western blot; human; loading ...; fig 5b
BD Biosciences XPO1 antibody (BD Bioscience, 611832) was used in western blot on human samples (fig 5b). Nucleic Acids Res (2017) ncbi
mouse monoclonal (17/Exportin-1/CRM1)
  • western blot; human; loading ...; fig 1a
BD Biosciences XPO1 antibody (BD Biosciences, 611832) was used in western blot on human samples (fig 1a). PLoS ONE (2015) ncbi
mouse monoclonal (17/Exportin-1/CRM1)
  • western blot; human; 1:1500; fig s4
BD Biosciences XPO1 antibody (BD biosciences, 611832) was used in western blot on human samples at 1:1500 (fig s4). PLoS ONE (2015) ncbi
mouse monoclonal (17/Exportin-1/CRM1)
  • western blot; human; 1:1000; fig 1
BD Biosciences XPO1 antibody (BD Transduction Labs, 611832) was used in western blot on human samples at 1:1000 (fig 1). Nat Neurosci (2015) ncbi
mouse monoclonal (17/Exportin-1/CRM1)
  • western blot; human
BD Biosciences XPO1 antibody (BD Transduction Laboratories, 611832) was used in western blot on human samples . Cell Mol Life Sci (2015) ncbi
mouse monoclonal (17/Exportin-1/CRM1)
  • immunocytochemistry; human
In order to localize CRM1 and its ribosome export adaptor NMD3 localize and study their roles in rRNA synthesis, BD Biosciences XPO1 antibody (BD Transduction, 611833) was used in immunocytochemistry on human samples . Nucleus (2013) ncbi
Articles Reviewed
  1. Sáinz Jaspeado M, Smith R, Plunde O, Pawelzik S, Jin Y, Nordling S, et al. Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium. Circulation. 2021;144:1629-1645 pubmed publisher
  2. Wang X, Zhang H, Sapio R, Yang J, Wong J, Zhang X, et al. SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer. Nat Commun. 2021;12:2259 pubmed publisher
  3. Van Alstyne M, Tattoli I, Delestrée N, Recinos Y, Workman E, Shihabuddin L, et al. Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Nat Neurosci. 2021;24:930-940 pubmed publisher
  4. Galbraith L, Mui E, Nixon C, Hedley A, Strachan D, Mackay G, et al. PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer. Oncogene. 2021;40:2355-2366 pubmed publisher
  5. Topalian S, Taube J, Pardoll D. Neoadjuvant checkpoint blockade for cancer immunotherapy. Science. 2020;367: pubmed publisher
  6. Oka M, Mura S, Otani M, Miyamoto Y, Nogami J, Maehara K, et al. Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells. elife. 2019;8: pubmed publisher
  7. Chatzifrangkeskou M, Pefani D, Eyres M, Vendrell I, Fischer R, Panková D, et al. RASSF1A is required for the maintenance of nuclear actin levels. EMBO J. 2019;38:e101168 pubmed publisher
  8. Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, et al. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017;8:14654 pubmed publisher
  9. Pauty J, Couturier A, Rodrigue A, Caron M, Coulombe Y, Dellaire G, et al. Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motif. Nucleic Acids Res. 2017;45:2644-2657 pubmed publisher
  10. Behrens R, Aligeti M, Pocock G, Higgins C, Sherer N. Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export. J Virol. 2017;91: pubmed publisher
  11. Cha K, Sen P, Raghunayakula S, Zhang X. The Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells. PLoS ONE. 2015;10:e0141309 pubmed publisher
  12. Yao M, Xie C, Kiang M, Teng Y, Harman D, Tiffen J, et al. Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells. Oncotarget. 2015;6:34458-74 pubmed publisher
  13. Khuperkar D, Helen M, Magre I, Joseph J. Inter-cellular transport of ran GTPase. PLoS ONE. 2015;10:e0125506 pubmed publisher
  14. Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, et al. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat Neurosci. 2015;18:511-20 pubmed publisher
  15. Hu Y, Liu X, Zhang A, Zhou H, Liu Z, Chen H, et al. CHD3 facilitates vRNP nuclear export by interacting with NES1 of influenza A virus NS2. Cell Mol Life Sci. 2015;72:971-82 pubmed publisher
  16. Germain M, Chatel Chaix L, Gagné B, Bonneil E, Thibault P, Pradezynski F, et al. Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches. Mol Cell Proteomics. 2014;13:184-203 pubmed publisher
  17. Bai B, Moore H, Laiho M. CRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis. Nucleus. 2013;4:315-25 pubmed publisher
  18. Chao H, Lai Y, Lu Y, Lin C, Mai W, Huang Y. NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3. Nucleic Acids Res. 2012;40:8484-98 pubmed