This is a Validated Antibody Database (VAD) review about human XBP1, based on 29 published articles (read how Labome selects the articles), using XBP1 antibody in all methods. It is aimed to help Labome visitors find the most suited XBP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
XBP1 synonym: TREB-5; TREB5; XBP-1; XBP2

Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s5e
Abcam XBP1 antibody (Abcam, ab37152) was used in western blot on mouse samples at 1:1000 (fig s5e). Arterioscler Thromb Vasc Biol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5c
  • western blot; mouse; 1:250; loading ...; fig 5b
Abcam XBP1 antibody (Abcam, ab37152) was used in immunohistochemistry on mouse samples at 1:200 (fig 5c) and in western blot on mouse samples at 1:250 (fig 5b). Int J Mol Sci (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4f
Abcam XBP1 antibody (Abcam, ab37152) was used in western blot on human samples (fig 4f). Theranostics (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4b
Abcam XBP1 antibody (Abcam, Ab37152) was used in western blot on human samples (fig 4b). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 7c
Abcam XBP1 antibody (Abcam, Ab37152) was used in western blot on mouse samples (fig 7c). Cell Mol Gastroenterol Hepatol (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 2s1a
Abcam XBP1 antibody (Abcam, Ab85546) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 2s1a). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 2h
Abcam XBP1 antibody (Abcam, ab37152) was used in western blot on mouse samples at 1:500 (fig 2h). J Biomed Sci (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 6
In order to characterize amelioration of neuronal cell death in a rat model of spontaneous obesity that is dietary-restricted through modulation of ubiquitin proteasome system, Abcam XBP1 antibody (Abcam, ab37152) was used in western blot on rat samples (fig 6). J Nutr Biochem (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig s3
In order to analyze induction of efficient anti-tumor immunity by vaccination with necroptotic cancer cells, Abcam XBP1 antibody (Abcam, ab37152) was used in western blot on mouse samples (fig s3). Cell Rep (2016) ncbi
domestic rabbit monoclonal (EPR4086)
  • western blot; human
Abcam XBP1 antibody (Epitomics, 3166-1) was used in western blot on human samples . Cell Death Dis (2014) ncbi
BioLegend
mouse monoclonal (143F)
  • immunocytochemistry; human; loading ...; fig 3c
BioLegend XBP1 antibody (Biolegend, 647501) was used in immunocytochemistry on human samples (fig 3c). Oncogenesis (2020) ncbi
mouse monoclonal (143F)
  • flow cytometry; human; loading ...; fig 2b
BioLegend XBP1 antibody (Biolegend, 143F) was used in flow cytometry on human samples (fig 2b). Arthritis Res Ther (2019) ncbi
mouse monoclonal (143F)
  • western blot; human; loading ...; fig 3d
In order to identify compounds that inhibit the proteasome 19S subunit Rpn11, BioLegend XBP1 antibody (BioLegend, 647502) was used in western blot on human samples (fig 3d). Nat Chem Biol (2017) ncbi
mouse monoclonal (143F)
  • western blot; human; loading ...; fig s2e
In order to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport, BioLegend XBP1 antibody (BioLegend, 647502) was used in western blot on human samples (fig s2e). Oncotarget (2016) ncbi
mouse monoclonal (143F)
  • western blot; human
BioLegend XBP1 antibody (Biolegend, 143F) was used in western blot on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (143F)
In order to study the effect of zymosan treatment on IL-23 production, BioLegend XBP1 antibody (Biolegend, 647501) was used . J Biol Chem (2014) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • proximity ligation assay; human; 1:1000; fig 4c
Novus Biologicals XBP1 antibody (Novus, NBP1-77681) was used in proximity ligation assay on human samples at 1:1000 (fig 4c). Nat Commun (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2C1F)
  • chromatin immunoprecipitation; human; fig 3a
  • western blot; human; 1:1000; fig 2b
Cell Signaling Technology XBP1 antibody (CST, 12782S) was used in chromatin immunoprecipitation on human samples (fig 3a) and in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; mouse; 1:1000; loading ...; fig 2c
Cell Signaling Technology XBP1 antibody (Cell Signaling Technology, 12,782) was used in western blot on mouse samples at 1:1000 (fig 2c). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology XBP1 antibody (Cell Signaling Technology, 12782) was used in western blot on human samples at 1:1000. Nat Commun (2020) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; human; loading ...; fig 1a, 5b, 7c
Cell Signaling Technology XBP1 antibody (CST, 12782) was used in western blot on human samples (fig 1a, 5b, 7c). PLoS Pathog (2019) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; human; 1:1000; loading ...; fig 7a
Cell Signaling Technology XBP1 antibody (Cell signaling technology, 12782s) was used in western blot on human samples at 1:1000 (fig 7a). Biol Res (2019) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; mouse; loading ...; fig 4d
Cell Signaling Technology XBP1 antibody (Cell Signaling Technology, 12782) was used in western blot on mouse samples (fig 4d). Immunity (2019) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; mouse; loading ...; fig s6a
Cell Signaling Technology XBP1 antibody (Cell Signaling Technology, 12782) was used in western blot on mouse samples (fig s6a). Nat Commun (2019) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; mouse; loading ...; fig 1h
Cell Signaling Technology XBP1 antibody (Cell Signaling Technology, 12782) was used in western blot on mouse samples (fig 1h). Cancer Cell (2019) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; mouse; loading ...; fig s5e
Cell Signaling Technology XBP1 antibody (Cell Signaling, 12782) was used in western blot on mouse samples (fig s5e). Nature (2017) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; mouse; loading ...; fig 5b
  • western blot; human; fig 2b
Cell Signaling Technology XBP1 antibody (Cell Signaling, 12782) was used in western blot on mouse samples (fig 5b) and in western blot on human samples (fig 2b). Mediators Inflamm (2016) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; human; fig 4
Cell Signaling Technology XBP1 antibody (Cell Signaling, 12782) was used in western blot on human samples (fig 4). elife (2016) ncbi
domestic rabbit monoclonal (D2C1F)
  • western blot; mouse; fig 3d
In order to test if 17-allylamino-demethoxygeldanamycin improves intestinal barrier function using two mouse graft versus host disease models, Cell Signaling Technology XBP1 antibody (Cell Signaling, 12782) was used in western blot on mouse samples (fig 3d). Oncogene (2016) ncbi
BD Biosciences
mouse monoclonal (Q3-695)
  • flow cytometry; mouse; loading ...; fig 5b
BD Biosciences XBP1 antibody (BD, Q3-695) was used in flow cytometry on mouse samples (fig 5b). J Cell Biol (2018) ncbi
Articles Reviewed
  1. Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang C, et al. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nat Commun. 2021;12:5321 pubmed publisher
  2. Dhawan U, Bhattacharya P, Narayanan S, Manickam V, Aggarwal A, Subramanian M. Hypercholesterolemia Impairs Clearance of Neutrophil Extracellular Traps and Promotes Inflammation and Atherosclerotic Plaque Progression. Arterioscler Thromb Vasc Biol. 2021;41:2598-2615 pubmed publisher
  3. Gaja Capdevila N, Hernández N, Zamanillo D, Vela J, Merlos M, Navarro X, et al. Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice. Int J Mol Sci. 2021;22: pubmed publisher
  4. Zhang X, Yu K, Ma L, Qian Z, Tian X, Miao Y, et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics. 2021;11:5650-5674 pubmed publisher
  5. Hua Y, Zhang K, Sheng J, Ning Z, Li Y, Shi W, et al. NUCB1 Suppresses Growth and Shows Additive Effects With Gemcitabine in Pancreatic Ductal Adenocarcinoma via the Unfolded Protein Response. Front Cell Dev Biol. 2021;9:641836 pubmed publisher
  6. Cao X, Shu Y, Chen Y, Xu Q, Guo G, Wu Z, et al. Mettl14-Mediated m6A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis. Cell Mol Gastroenterol Hepatol. 2021;12:633-651 pubmed publisher
  7. Yin S, Li L, Tao Y, Yu J, Wei S, Liu M, et al. The Inhibitory Effect of Artesunate on Excessive Endoplasmic Reticulum Stress Alleviates Experimental Colitis in Mice. Front Pharmacol. 2021;12:629798 pubmed publisher
  8. Brockway S, Wang G, Jackson J, Amici D, Takagishi S, Clutter M, et al. Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq. Nat Commun. 2020;11:5722 pubmed publisher
  9. Pavlovic N, Calitz C, Thanapirom K, Mazza G, Rombouts K, Gerwins P, et al. Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma. elife. 2020;9: pubmed publisher
  10. Zang M, Guo J, Liu L, Jin F, Feng X, An G, et al. Cdc37 suppression induces plasma cell immaturation and bortezomib resistance in multiple myeloma via Xbp1s. Oncogenesis. 2020;9:31 pubmed publisher
  11. Modi J, Menzie Suderam J, Xu H, Trujillo P, Medley K, Marshall M, et al. Mode of action of granulocyte-colony stimulating factor (G-CSF) as a novel therapy for stroke in a mouse model. J Biomed Sci. 2020;27:19 pubmed publisher
  12. Johnston B, Pringle E, McCormick C. KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication. PLoS Pathog. 2019;15:e1008185 pubmed publisher
  13. Wang X, Peng P, Pan Z, Fang Z, Lu W, Liu X. Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells. Biol Res. 2019;52:34 pubmed publisher
  14. Ye Y, Liu M, Tang L, Du F, Liu Y, Hao P, et al. Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis. Arthritis Res Ther. 2019;21:92 pubmed publisher
  15. Wu J, Ma S, Sandhoff R, Ming Y, Hotz Wagenblatt A, Timmerman V, et al. Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness. Immunity. 2019;50:1218-1231.e5 pubmed publisher
  16. Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, et al. Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice. Nat Commun. 2019;10:1492 pubmed publisher
  17. Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson F, et al. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019;35:204-220.e9 pubmed publisher
  18. Tang C, Chang S, Paton A, Paton J, Gabrilovich D, Ploegh H, et al. Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization. J Cell Biol. 2018;217:1739-1755 pubmed publisher
  19. Li J, Yakushi T, Parlati F, MacKinnon A, Pérez C, Ma Y, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017;13:486-493 pubmed publisher
  20. Genovese G, Carugo A, TEPPER J, Robinson F, Li L, Svelto M, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017;542:362-366 pubmed publisher
  21. Geraghty P, Baumlin N, SALATHE M, Foronjy R, D Armiento J. Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure. Mediators Inflamm. 2016;2016:9461289 pubmed publisher
  22. Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher
  23. Dejesus R, Moretti F, McAllister G, Wang Z, Bergman P, Liu S, et al. Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62. elife. 2016;5: pubmed publisher
  24. Shruthi K, Reddy S, Reddy P, Shivalingam P, Harishankar N, Reddy G. Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. J Nutr Biochem. 2016;33:73-81 pubmed publisher
  25. Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed publisher
  26. Joly A, Deepti A, Seignez A, Goloudina A, Hebrard S, Schmitt E, et al. The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development. Oncogene. 2016;35:2842-51 pubmed publisher
  27. D Osualdo A, Anania V, Yu K, Lill J, Kaufman R, Matsuzawa S, et al. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0130635 pubmed publisher
  28. Li W, Ouyang Z, Zhang Q, Wang L, Shen Y, Gu Y, et al. SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2. Cell Death Dis. 2014;5:e1581 pubmed publisher
  29. Rodriguez M, Domingo E, Alonso S, Frade J, Eiros J, Crespo M, et al. The unfolded protein response and the phosphorylations of activating transcription factor 2 in the trans-activation of il23a promoter produced by ?-glucans. J Biol Chem. 2014;289:22942-57 pubmed publisher