This is a Validated Antibody Database (VAD) review about human WRAP53, based on 4 published articles (read how Labome selects the articles), using WRAP53 antibody in all methods. It is aimed to help Labome visitors find the most suited WRAP53 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
WRAP53 synonym: DKCB3; TCAB1; WDR79; telomerase Cajal body protein 1; WD repeat-containing protein 79; WD repeat-containing protein WRAP53; WD40 protein Wrap53; WD40 repeat-containing protein antisense to TP53; WD40 repeat-containing protein encoding RNA antisense to p53

Knockout validation
Novus Biologicals
rabbit polyclonal
  • immunocytochemistry knockout validation; human; 1:300; fig 4
  • western blot knockout validation; human; 1:2000; fig 4
  • immunoprecipitation; human; fig 4
Novus Biologicals WRAP53 antibody (Novus Biologicals, NB100-68252) was used in immunocytochemistry knockout validation on human samples at 1:300 (fig 4), in western blot knockout validation on human samples at 1:2000 (fig 4) and in immunoprecipitation on human samples (fig 4). elife (2016) ncbi
Abnova
mouse monoclonal (1F12)
  • immunocytochemistry; rat; 1:200; fig 2
  • immunohistochemistry; rat; 1:100; fig 4
  • western blot; rat; 1:2000; fig 2
Abnova WRAP53 antibody (ABNOVA, H00055135-M04) was used in immunocytochemistry on rat samples at 1:200 (fig 2), in immunohistochemistry on rat samples at 1:100 (fig 4) and in western blot on rat samples at 1:2000 (fig 2). Acta Neuropathol Commun (2016) ncbi
mouse monoclonal (1F12)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 3
Abnova WRAP53 antibody (Abnova, H00055135-M0) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 3). Cell Death Dis (2015) ncbi
mouse polyclonal
  • immunocytochemistry; human
Abnova WRAP53 antibody (Abnova, H00055135-B01P) was used in immunocytochemistry on human samples . Genes Dev (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human
Abnova WRAP53 antibody (Abnova, H00055135-D01P) was used in immunocytochemistry on human samples . Genes Dev (2014) ncbi
Novus Biologicals
rabbit polyclonal
  • immunocytochemistry knockout validation; human; 1:300; fig 4
  • western blot knockout validation; human; 1:2000; fig 4
  • immunoprecipitation; human; fig 4
Novus Biologicals WRAP53 antibody (Novus Biologicals, NB100-68252) was used in immunocytochemistry knockout validation on human samples at 1:300 (fig 4), in western blot knockout validation on human samples at 1:2000 (fig 4) and in immunoprecipitation on human samples (fig 4). elife (2016) ncbi
Bethyl
rabbit polyclonal
  • immunocytochemistry; human
Bethyl WRAP53 antibody (Bethyl, A301-442A-1) was used in immunocytochemistry on human samples . Genes Dev (2014) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; human
Proteintech Group WRAP53 antibody (Proteintech, 14761-1-AP) was used in immunocytochemistry on human samples . Genes Dev (2014) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunocytochemistry; human; fig 3
  • immunohistochemistry; human; 1:25; fig 1
Sigma-Aldrich WRAP53 antibody (Atlas Antibodies, HPA023026) was used in immunocytochemistry on human samples (fig 3) and in immunohistochemistry on human samples at 1:25 (fig 1). Cell Death Dis (2015) ncbi
Articles Reviewed
  1. Vogan J, Zhang X, Youmans D, Regalado S, Johnson J, Hockemeyer D, et al. Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. elife. 2016;5: pubmed publisher
  2. Mata Garrido J, Casafont I, Tapia O, Berciano M, Lafarga M. Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization. Acta Neuropathol Commun. 2016;4:41 pubmed publisher
  3. Hedström E, Pederiva C, Farnebo J, Nodin B, Jirström K, Brennan D, et al. Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome. Cell Death Dis. 2015;6:e1892 pubmed publisher
  4. Henriksson S, Rassoolzadeh H, Hedström E, Coucoravas C, Julner A, Goldstein M, et al. The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair. Genes Dev. 2014;28:2726-38 pubmed publisher