This is a Validated Antibody Database (VAD) review about human WDR62, based on 3 published articles (read how Labome selects the articles), using WDR62 antibody in all methods. It is aimed to help Labome visitors find the most suited WDR62 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
WDR62 synonym: C19orf14; MCPH2; WD repeat-containing protein 62; microcephaly, primary autosomal recessive 2; truncated WDR62

Bethyl
rabbit polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig s11a
  • immunohistochemistry; human; loading ...; fig 5e
  • immunohistochemistry; mouse; loading ...; fig 3a
In order to reveal critical and diverse functions of WD repeat domain 62 in neocortical development, Bethyl WDR62 antibody (Bethyl Lab, A301-560A) was used in immunocytochemistry on human samples at 1:500 (fig s11a), in immunohistochemistry on human samples (fig 5e) and in immunohistochemistry on mouse samples (fig 3a). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 6
Bethyl WDR62 antibody (Bethyl, A301-560A) was used in western blot on human samples (fig 6). J Cell Sci (2015) ncbi
Novus Biologicals
rabbit polyclonal
  • western blot; human; 1:5000; loading ...; fig s15
In order to identify MAPKBP1 mutations as a genetic cause of juvenile or late-onset and cilia-independent nephronophthisis, Novus Biologicals WDR62 antibody (NOVUS, NB100-77302) was used in western blot on human samples at 1:5000 (fig s15). Am J Hum Genet (2017) ncbi
Articles Reviewed
  1. Sgourdou P, Mishra Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep. 2017;7:43708 pubmed publisher
  2. Macia M, Halbritter J, Delous M, Bredrup C, Gutter A, Filhol E, et al. Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis. Am J Hum Genet. 2017;100:323-333 pubmed publisher
  3. Lim N, Yeap Y, Zhao T, Yip Y, Wong S, Xu D, et al. Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules. J Cell Sci. 2015;128:527-40 pubmed