This is a Validated Antibody Database (VAD) review about human WDR5, based on 15 published articles (read how Labome selects the articles), using WDR5 antibody in all methods. It is aimed to help Labome visitors find the most suited WDR5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
WDR5 synonym: BIG-3; CFAP89; SWD3

Abcam
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 8b
Abcam WDR5 antibody (Abcam, ab245479) was used in immunohistochemistry on mouse samples (fig 8b). J Hepatocell Carcinoma (2021) ncbi
domestic rabbit monoclonal (EPR11350)
  • western blot; human; fig 5d
Abcam WDR5 antibody (Abcam, ab178410) was used in western blot on human samples (fig 5d). Cell (2018) ncbi
mouse monoclonal
  • chromatin immunoprecipitation; human; fig 5
Abcam WDR5 antibody (Abcam, ab56919) was used in chromatin immunoprecipitation on human samples (fig 5). Mol Cell Biol (2016) ncbi
mouse monoclonal
  • RNA immunoprecipitation; human; fig 3
  • western blot; human; 1:1000; fig 3
Abcam WDR5 antibody (Abcam, ab56919) was used in RNA immunoprecipitation on human samples (fig 3) and in western blot on human samples at 1:1000 (fig 3). Stem Cell Reports (2015) ncbi
mouse monoclonal
  • RNA immunoprecipitation; human; 1:500; fig s9
  • chromatin immunoprecipitation; human; fig 5
Abcam WDR5 antibody (Abcam, ab56919) was used in RNA immunoprecipitation on human samples at 1:500 (fig s9) and in chromatin immunoprecipitation on human samples (fig 5). Nat Commun (2015) ncbi
mouse monoclonal
  • flow cytometry; human
  • western blot; human
Abcam WDR5 antibody (Abcam, ab56919) was used in flow cytometry on human samples and in western blot on human samples . Oncogene (2015) ncbi
mouse monoclonal
  • chromatin immunoprecipitation; human; fig 3
Abcam WDR5 antibody (abcam, ab56919) was used in chromatin immunoprecipitation on human samples (fig 3). Nucleic Acids Res (2014) ncbi
Invitrogen
mouse monoclonal (7B11)
  • immunohistochemistry - paraffin section; pigs ; 1:100; loading ...; fig 8f
In order to generate and characterize the immune system of CAG-LEA29Y transgenic pigs, Invitrogen WDR5 antibody (Invitrogen, 7B11) was used in immunohistochemistry - paraffin section on pigs samples at 1:100 (fig 8f). PLoS ONE (2016) ncbi
mouse monoclonal (7B11)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2b
In order to investigate the molecular mechanisms that contribute to hepatocellular carcinoma, Invitrogen WDR5 antibody (Zymed Laboratories, 7B11) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2b). Dig Dis Sci (2016) ncbi
mouse monoclonal (7B11)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2b
In order to determine the role of p53-induced death domain protein in hepatocellular carcinoma development, Invitrogen WDR5 antibody (Zymed, 7B11) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2b). Tumour Biol (2016) ncbi
mouse monoclonal (7B11)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3e
In order to examine the methylation and inactivation of hMLH1 in the progression of sessile serrated lesions, Invitrogen WDR5 antibody (Invitrogen, 7B11) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3e). Histopathology (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-9)
  • western blot; human; fig 6c
Santa Cruz Biotechnology WDR5 antibody (Santa Cruz, sc-393080) was used in western blot on human samples (fig 6c). FEBS J (2018) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D9E1I)
  • chromatin immunoprecipitation; mouse; ; loading ...; fig 4c
Cell Signaling Technology WDR5 antibody (Cell Signaling, 13105) was used in chromatin immunoprecipitation on mouse samples at (fig 4c). Nature (2019) ncbi
domestic rabbit monoclonal (D9E1I)
  • western blot; human; fig s3
Cell Signaling Technology WDR5 antibody (Cell signaling, 13105) was used in western blot on human samples (fig s3). Genome Biol (2016) ncbi
domestic rabbit monoclonal (D9E1I)
  • western blot; human; fig 1
Cell Signaling Technology WDR5 antibody (Cell Signaling, D9E1I) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
Articles Reviewed
  1. Zhang Y, Zhang H, Wu S. LncRNA-CCDC144NL-AS1 Promotes the Development of Hepatocellular Carcinoma by Inducing WDR5 Expression via Sponging miR-940. J Hepatocell Carcinoma. 2021;8:333-348 pubmed publisher
  2. El Brolosy M, Kontarakis Z, Rossi A, Kuenne C, Günther S, Fukuda N, et al. Genetic compensation triggered by mutant mRNA degradation. Nature. 2019;: pubmed publisher
  3. Hoshii T, Cifani P, Feng Z, Huang C, Koche R, Chen C, et al. A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response. Cell. 2018;172:1007-1021.e17 pubmed publisher
  4. Bieluszewska A, Weglewska M, Bieluszewski T, Lesniewicz K, Poreba E. PKA-binding domain of AKAP8 is essential for direct interaction with DPY30 protein. FEBS J. 2018;285:947-964 pubmed publisher
  5. Bähr A, Käser T, Kemter E, Gerner W, Kurome M, Baars W, et al. Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PLoS ONE. 2016;11:e0155676 pubmed publisher
  6. Zong G, Xu Z, Zhang S, Shen Y, Qiu H, Zhu G, et al. CD109 Mediates Cell Survival in Hepatocellular Carcinoma Cells. Dig Dis Sci. 2016;61:2303-14 pubmed publisher
  7. G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  8. Shi W, Huang W, Chen Y, Zhang S, Xu P, Gu X, et al. Low expression of PIDD is associated with cell proliferation and apoptosis in hepatocellular carcinoma. Tumour Biol. 2016;37:10447-57 pubmed publisher
  9. Lee E, Chun S, Kim M, Jang S, Kim D, Lee D, et al. Reappraisal of hMLH1 promoter methylation and protein expression status in the serrated neoplasia pathway. Histopathology. 2016;69:198-210 pubmed publisher
  10. Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed publisher
  11. Thomas L, Foshage A, Weissmiller A, Popay T, Grieb B, Qualls S, et al. Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif. Oncogene. 2016;35:3613-8 pubmed publisher
  12. Xiao T, Liu L, Li H, Sun Y, Luo H, Li T, et al. Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPα. Stem Cell Reports. 2015;5:856-65 pubmed publisher
  13. Spurlock C, Tossberg J, Guo Y, Collier S, Crooke P, Aune T. Expression and functions of long noncoding RNAs during human T helper cell differentiation. Nat Commun. 2015;6:6932 pubmed publisher
  14. Mungamuri S, Wang S, Manfredi J, Gu W, Aaronson S. Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters. Oncogene. 2015;34:2461-70 pubmed publisher
  15. Ullius A, Lüscher Firzlaff J, Costa I, Walsemann G, Forst A, Gusmao E, et al. The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification. Nucleic Acids Res. 2014;42:6901-20 pubmed publisher