This is a Validated Antibody Database (VAD) review about human WAPL, based on 4 published articles (read how Labome selects the articles), using WAPL antibody in all methods. It is aimed to help Labome visitors find the most suited WAPL antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
WAPL synonym: FOE; KIAA0261; WAPAL; wings apart-like protein homolog; friend of EBNA2 (Epstein-Barr virus nuclear protein 2); friend of EBNA2 protein

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (A-7)
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Santa Cruz Biotechnology WAPL antibody (Santa Cruz, A-7) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Cell (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-7)
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Santa Cruz Biotechnology WAPL antibody (Santa Cruz, A-7) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Cell (2017) ncbi
mouse monoclonal (A-7)
  • western blot; human; fig 4
Santa Cruz Biotechnology WAPL antibody (Santa Cruz Biotechnology, A-7) was used in western blot on human samples (fig 4). PLoS Genet (2016) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; mouse; fig s3b
  • western blot; mouse; fig s2b
In order to elucidate how NEK1 regulates cohesin assembly on chromosomes at meiotic prophase I, Proteintech Group WAPL antibody (Proteintech, 16370-1-AP) was used in immunocytochemistry on mouse samples (fig s3b) and in western blot on mouse samples (fig s2b). Cell Rep (2016) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
Bethyl WAPL antibody (Bethyl, A300-268 A) was used in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
Articles Reviewed
  1. Haarhuis J, van der Weide R, Blomen V, Yáñez Cuna J, Amendola M, van Ruiten M, et al. The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension. Cell. 2017;169:693-707.e14 pubmed publisher
  2. Brieño Enríquez M, Moak S, Toledo M, Filter J, Gray S, Barbero J, et al. Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse. Cell Rep. 2016;17:977-986 pubmed publisher
  3. Kim J, He X, Orr B, Wutz G, Hill V, Peters J, et al. Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2. PLoS Genet. 2016;12:e1005865 pubmed publisher
  4. de Lange J, Faramarz A, Oostra A, de Menezes R, van der Meulen I, Rooimans M, et al. Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function. Nat Commun. 2015;6:8399 pubmed publisher