This is a Validated Antibody Database (VAD) review about human VSX2, based on 23 published articles (read how Labome selects the articles), using VSX2 antibody in all methods. It is aimed to help Labome visitors find the most suited VSX2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
VSX2 synonym: CHX10; HOX10; MCOP2; MCOPCB3; RET1

Santa Cruz Biotechnology
mouse monoclonal (E-12)
  • immunohistochemistry - frozen section; human; fig 1b, 2k
  • flow cytometry; human; fig s4d
  • immunohistochemistry - frozen section; African green monkey; loading ...; fig s6a
Santa Cruz Biotechnology VSX2 antibody (Santa Cruz, sc-365519) was used in immunohistochemistry - frozen section on human samples (fig 1b, 2k), in flow cytometry on human samples (fig s4d) and in immunohistochemistry - frozen section on African green monkey samples (fig s6a). iScience (2022) ncbi
mouse monoclonal (E-12)
  • immunohistochemistry; mouse; 1:100; fig 2i
Santa Cruz Biotechnology VSX2 antibody (Santa Cruz Biotechnology, sc-365519) was used in immunohistochemistry on mouse samples at 1:100 (fig 2i). Sci Transl Med (2021) ncbi
mouse monoclonal (E-12)
  • immunohistochemistry; mouse; 1:250; loading ...; fig 3e
Santa Cruz Biotechnology VSX2 antibody (Santa Cruz, sc-365519) was used in immunohistochemistry on mouse samples at 1:250 (fig 3e). Eneuro (2021) ncbi
mouse monoclonal (E-12)
  • immunohistochemistry; mouse; loading ...; fig 1g, 2a
Santa Cruz Biotechnology VSX2 antibody (Santa cruz, sc-365519) was used in immunohistochemistry on mouse samples (fig 1g, 2a). iScience (2021) ncbi
mouse monoclonal (E-12)
  • immunohistochemistry; mouse; 1:100; fig 2i
Santa Cruz Biotechnology VSX2 antibody (Santa Cruz Biotechnology, sc-365519) was used in immunohistochemistry on mouse samples at 1:100 (fig 2i). Development (2021) ncbi
mouse monoclonal (D-11)
  • flow cytometry; mouse; loading ...; fig 3c
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 3d
Santa Cruz Biotechnology VSX2 antibody (Santa Cruz, sc-374151) was used in flow cytometry on mouse samples (fig 3c) and in immunocytochemistry on mouse samples at 1:1000 (fig 3d). Exp Neurol (2016) ncbi
Abcam
domestic sheep polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig s1c
Abcam VSX2 antibody (Abcam, ab16141) was used in immunohistochemistry on mouse samples at 1:200 (fig s1c). J Neuroinflammation (2021) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; fig 2b
Abcam VSX2 antibody (Abcam, Ab16141) was used in immunocytochemistry on human samples (fig 2b). Mol Ther Methods Clin Dev (2021) ncbi
domestic sheep polyclonal
  • immunohistochemistry; mouse; 1:500; fig 4
Abcam VSX2 antibody (abcam, ab16141) was used in immunohistochemistry on mouse samples at 1:500 (fig 4). Sci Rep (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal (JB42-35)
  • immunohistochemistry; human; 1:200; fig 2A
In order to establish an application to generate retinal pigmented epithelium from induced pluripotent stem cells, Novus Biologicals VSX2 antibody (Novus, NBP184476) was used in immunohistochemistry on human samples at 1:200 (fig 2A). PLoS ONE (2017) ncbi
Exalpha Biologicals
  • immunohistochemistry; mouse; 1:200; loading ...; fig 8g
Exalpha Biologicals VSX2 antibody (Exalpha, X1180P) was used in immunohistochemistry on mouse samples at 1:200 (fig 8g). Front Cell Dev Biol (2021) ncbi
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5b
Exalpha Biologicals VSX2 antibody (Exalpha Biologicals, X1180P) was used in immunohistochemistry on mouse samples at 1:200 (fig 5b). Sci Rep (2021) ncbi
  • immunohistochemistry - frozen section; mouse; loading ...
Exalpha Biologicals VSX2 antibody (Exalpha, X1180P) was used in immunohistochemistry - frozen section on mouse samples . Cell Rep (2021) ncbi
  • immunohistochemistry - frozen section; mouse; 1:300; loading ...; fig 2h
Exalpha Biologicals VSX2 antibody (Exalpha, X1180-P) was used in immunohistochemistry - frozen section on mouse samples at 1:300 (fig 2h). elife (2020) ncbi
  • immunocytochemistry; mouse; 1:200; loading ...; fig s3
  • immunohistochemistry; mouse; 1:200; loading ...; fig s1
Exalpha Biologicals VSX2 antibody (Exalpha Biological, X1180P) was used in immunocytochemistry on mouse samples at 1:200 (fig s3) and in immunohistochemistry on mouse samples at 1:200 (fig s1). Oncogenesis (2020) ncbi
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s2e
In order to investigate the role of Pax6 in retinogenesis, Exalpha Biologicals VSX2 antibody (Exalpha, X1180P) was used in immunohistochemistry on mouse samples at 1:1000 (fig s2e). Dev Biol (2017) ncbi
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; tbl 2
In order to examine the effects of retinal progenitor cell proliferation on the spatiotemporal differentiation and synaptic development of rods and bipolar cells in early postnatal gestational lead exposure retinas, Exalpha Biologicals VSX2 antibody (Exalpha Biologicals, X1180P) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (tbl 2). Mol Vis (2016) ncbi
  • immunocytochemistry; human; 1:100; fig 2
In order to develop clinically-compatible methods to generate photoreceptor precursor cells from adult skin in a non-profit cGMP environment, Exalpha Biologicals VSX2 antibody (Exalpha Biologicals, X1180P) was used in immunocytochemistry on human samples at 1:100 (fig 2). Sci Rep (2016) ncbi
  • immunohistochemistry; mouse; 1:100; fig 4
In order to determine tissue specific functions of DLL1 or DLL4 using transgenic mice, Exalpha Biologicals VSX2 antibody (Exalpha, X1180P) was used in immunohistochemistry on mouse samples at 1:100 (fig 4). PLoS Genet (2015) ncbi
  • immunohistochemistry; mouse; 1:1600
Exalpha Biologicals VSX2 antibody (Exalpha, x1180p) was used in immunohistochemistry on mouse samples at 1:1600. Mol Brain (2015) ncbi
  • immunohistochemistry - frozen section; mouse; 1:600; loading ...; fig 4h
Exalpha Biologicals VSX2 antibody (Exalpha Biologicals, X1180P) was used in immunohistochemistry - frozen section on mouse samples at 1:600 (fig 4h). Dev Dyn (2015) ncbi
  • immunohistochemistry - frozen section; mouse; 1:300
Exalpha Biologicals VSX2 antibody (Exalpha, X1180P) was used in immunohistochemistry - frozen section on mouse samples at 1:300. J Comp Neurol (2009) ncbi
  • immunohistochemistry - frozen section; mouse; 1:300
Exalpha Biologicals VSX2 antibody (Exalpha, X1180P) was used in immunohistochemistry - frozen section on mouse samples at 1:300. J Comp Neurol (2008) ncbi
Articles Reviewed
  1. Yamasaki S, Tu H, Matsuyama T, Horiuchi M, Hashiguchi T, Sho J, et al. A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation. iScience. 2022;25:103657 pubmed publisher
  2. Bellail A, Jin H, Lo H, Jung S, Hamdouchi C, Kim D, et al. Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors. Sci Transl Med. 2021;13:eabh1486 pubmed publisher
  3. Zhang P, Schlecht A, Wolf J, Boneva S, Laich Y, Koch J, et al. The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation. J Neuroinflammation. 2021;18:215 pubmed publisher
  4. Pensieri P, Mantilleri A, Plassard D, Furukawa T, Moya K, Prochiantz A, et al. Photoreceptor cKO of OTX2 Enhances OTX2 Intercellular Transfer in the Retina and Causes Photophobia. Eneuro. 2021;8: pubmed publisher
  5. Matsuyama T, Tu H, Sun J, Hashiguchi T, Akiba R, Sho J, et al. Genetically engineered stem cell-derived retinal grafts for improved retinal reconstruction after transplantation. iScience. 2021;24:102866 pubmed publisher
  6. Völkner M, Kurth T, Schor J, Ebner L, Bardtke L, Kavak C, et al. Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture. Front Cell Dev Biol. 2021;9:645704 pubmed publisher
  7. Salas A, Duarri A, Fontrodona L, Ram xed rez D, Badia A, Isla Magran xe9 H, et al. Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration. Mol Ther Methods Clin Dev. 2021;20:688-702 pubmed publisher
  8. Mattar P, Jolicoeur C, Dang T, Shah S, Clark B, Cayouette M. A Casz1-NuRD complex regulates temporal identity transitions in neural progenitors. Sci Rep. 2021;11:3858 pubmed publisher
  9. Exelby K, Herrera Delgado E, Perez L, Perez Carrasco R, Sagner A, Metzis V, et al. Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks. Development. 2021;148: pubmed publisher
  10. Burger C, Albrecht N, Jiang D, Liang J, Poch xe9 R, Samuel M. LKB1 and AMPK instruct cone nuclear position to modify visual function. Cell Rep. 2021;34:108698 pubmed publisher
  11. Vigouroux R, Cesar Q, Chedotal A, Nguyen Ba Charvet K. Revisiting the role of Dcc in visual system development with a novel eye clearing method. elife. 2020;9: pubmed publisher
  12. Zocchi L, Mehta A, Wu S, Wu J, Gu Y, Wang J, et al. Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. Oncogenesis. 2020;9:25 pubmed publisher
  13. Remez L, Onishi A, Menuchin Lasowski Y, Biran A, Blackshaw S, Wahlin K, et al. Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis. Dev Biol. 2017;432:140-150 pubmed publisher
  14. Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed publisher
  15. Chaney S, Mukherjee S, Giddabasappa A, Rueda E, Hamilton W, Johnson J, et al. Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation. Mol Vis. 2016;22:1468-1489 pubmed
  16. Wiley L, Burnight E, DeLuca A, Anfinson K, Cranston C, Kaalberg E, et al. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 2016;6:30742 pubmed publisher
  17. Hughes S, Rodgers J, Hickey D, Foster R, Peirson S, Hankins M. Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways. Sci Rep. 2016;6:28086 pubmed publisher
  18. Iyer N, Huettner J, Butts J, Brown C, Sakiyama Elbert S. Generation of highly enriched V2a interneurons from mouse embryonic stem cells. Exp Neurol. 2016;277:305-316 pubmed publisher
  19. Preuße K, Tveriakhina L, Schuster Gossler K, Gaspar C, Rosa A, Henrique D, et al. Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo. PLoS Genet. 2015;11:e1005328 pubmed publisher
  20. Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M. Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015;8:28 pubmed publisher
  21. Zou M, Luo H, Xiang M. Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015;244:86-97 pubmed publisher
  22. Voinescu P, Emanuela P, Kay J, Sanes J. Birthdays of retinal amacrine cell subtypes are systematically related to their molecular identity and soma position. J Comp Neurol. 2009;517:737-50 pubmed publisher
  23. Poche R, Furuta Y, Chaboissier M, Schedl A, Behringer R. Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development. J Comp Neurol. 2008;510:237-50 pubmed publisher