This is a Validated Antibody Database (VAD) review about human VPS11, based on 4 published articles (read how Labome selects the articles), using VPS11 antibody in all methods. It is aimed to help Labome visitors find the most suited VPS11 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
VPS11 synonym: END1; HLD12; PEP5; RNF108; hVPS11; vacuolar protein sorting-associated protein 11 homolog; RING finger protein 108; vacuolar protein sorting 11 homolog

Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; loading ...; fig 5e
In order to research the role of Pacer, Stx17 and class III PI3K and HOPS complexes in autophagosome maturation, Santa Cruz Biotechnology VPS11 antibody (Santa Cruz, sc-515094) was used in western blot on human samples (fig 5e). Mol Cell (2017) ncbi
mouse monoclonal (S-38)
  • western blot; mouse; fig 4c
Santa Cruz Biotechnology VPS11 antibody (Santa Cruz Biotechnology, sc-100893) was used in western blot on mouse samples (fig 4c). Autophagy (2015) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; fig 4
Bethyl VPS11 antibody (Bethyl Laboratories, A303-528A) was used in western blot on human samples (fig 4). PLoS Genet (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; human; loading ...; fig 6a
In order to investigate Rab7 and Arl8b crosstalk, Abcam VPS11 antibody (Abcam, ab125083) was used in western blot on human samples (fig 6a). J Cell Biol (2017) ncbi
Articles Reviewed
  1. Marwaha R, Arya S, Jagga D, Kaur H, Tuli A, Sharma M. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol. 2017;216:1051-1070 pubmed publisher
  2. Cheng X, Ma X, Ding X, Li L, Jiang X, Shen Z, et al. Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17. Mol Cell. 2017;65:1029-1043.e5 pubmed publisher
  3. Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye L, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016;12:e1005848 pubmed publisher
  4. Zhen Y, Li W. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. Autophagy. 2015;11:1608-22 pubmed publisher