This is a Validated Antibody Database (VAD) review about human VEGF-C, based on 8 published articles (read how Labome selects the articles), using VEGF-C antibody in all methods. It is aimed to help Labome visitors find the most suited VEGF-C antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
VEGF-C synonym: Flt4-L; LMPH1D; VRP; vascular endothelial growth factor C; FLT4 ligand DHM; vascular endothelial growth factor-related protein

Santa Cruz Biotechnology
mouse monoclonal (A-5)
  • western blot; human; fig 2
Santa Cruz Biotechnology VEGF-C antibody (Santa Cruz, sc74584) was used in western blot on human samples (fig 2). Onco Targets Ther (2016) ncbi
mouse monoclonal (30AT1174.77.260)
  • western blot; mouse; fig 1
  • western blot; human; fig 8
In order to analyze mediation of pathological retinal neovascularization via modulating DLL4-NOTCH1 signaling due to the cyclic AMP response element binding protein, Santa Cruz Biotechnology VEGF-C antibody (Santa Cruz Biotechnology, SC-130,289) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 8). EBioMedicine (2015) ncbi
R&D Systems
goat polyclonal
  • immunohistochemistry - paraffin section; human
R&D Systems VEGF-C antibody (R&D SYSTEMS, AF752) was used in immunohistochemistry - paraffin section on human samples . Oral Surg Oral Med Oral Pathol Oral Radiol (2015) ncbi
goat polyclonal
  • immunohistochemistry - paraffin section; human; 1:50; fig 1f
  • western blot; human; fig 1d
In order to study the increased expression of TEM7 and VEGF-C to promote angiogenesis of gliobastomas by a gain-of-function GLI1 transcription factor, TGLI1, R&D Systems VEGF-C antibody (R&D, AF752) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1f) and in western blot on human samples (fig 1d). Oncotarget (2015) ncbi
goat polyclonal
  • immunohistochemistry - paraffin section; human; 1:100
R&D Systems VEGF-C antibody (R&D Systems, AF752) was used in immunohistochemistry - paraffin section on human samples at 1:100. Oncol Lett (2013) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:500; fig 2
Proteintech Group VEGF-C antibody (Proteintech, 22601-1-AP) was used in western blot on human samples at 1:500 (fig 2). PLoS ONE (2016) ncbi
Abcam
rabbit polyclonal
  • ELISA; mouse
Abcam VEGF-C antibody (Abcam, ab9546) was used in ELISA on mouse samples . Blood (2013) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; loading ...; fig s6d
Cell Signaling Technology VEGF-C antibody (Cell signaling, 2445) was used in western blot on mouse samples (fig s6d). Proc Natl Acad Sci U S A (2017) ncbi
Articles Reviewed
  1. Jiang Y, Lin X, Tang Z, Lee C, Tian G, Du Y, et al. Critical role of caveolin-1 in ocular neovascularization and multitargeted antiangiogenic effects of cavtratin via JNK. Proc Natl Acad Sci U S A. 2017;114:10737-10742 pubmed publisher
  2. Ding X, Qiu L, Zhang L, Xi J, Li D, Huang X, et al. The role of semaphorin 4D as a potential biomarker for antiangiogenic therapy in colorectal cancer. Onco Targets Ther. 2016;9:1189-204 pubmed publisher
  3. Liu L, Tong Q, Liu S, Cui J, Zhang Q, Sun W, et al. ZEB1 Upregulates VEGF Expression and Stimulates Angiogenesis in Breast Cancer. PLoS ONE. 2016;11:e0148774 pubmed publisher
  4. Singh N, Kotla S, Kumar R, Rao G. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine. 2015;2:1767-84 pubmed publisher
  5. Matsui T, Shigeta T, Umeda M, Komori T. Vascular endothelial growth factor C (VEGF-C) expression predicts metastasis in tongue cancer. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;120:436-42 pubmed publisher
  6. Carpenter R, Paw I, Zhu H, Sirkisoon S, Xing F, Watabe K, et al. The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis. Oncotarget. 2015;6:22653-65 pubmed
  7. Guo J, Lou W, Ji Y, Zhang S. Effect of CCR7, CXCR4 and VEGF-C on the lymph node metastasis of human pancreatic ductal adenocarcinoma. Oncol Lett. 2013;5:1572-1578 pubmed
  8. Singh N, Tiem M, Watkins R, Cho Y, Wang Y, Olsen T, et al. Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity. Blood. 2013;121:4242-9 pubmed publisher