This is a Validated Antibody Database (VAD) review about human VDR, based on 32 published articles (read how Labome selects the articles), using VDR antibody in all methods. It is aimed to help Labome visitors find the most suited VDR antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
VDR synonym: NR1I1; PPP1R163

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (D-6)
  • immunohistochemistry knockout validation; mouse; fig 3B
  • immunohistochemistry - frozen section; mouse; fig 3B
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in immunohistochemistry knockout validation on mouse samples (fig 3B) and in immunohistochemistry - frozen section on mouse samples (fig 3B). PLoS ONE (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR4552)
  • western blot knockout validation; human; loading ...; fig 8b
  • immunohistochemistry knockout validation; mouse; loading ...; fig 5d
  • western blot knockout validation; mouse; loading ...; fig 5f
Abcam VDR antibody (Abcam, ab109234) was used in western blot knockout validation on human samples (fig 8b), in immunohistochemistry knockout validation on mouse samples (fig 5d) and in western blot knockout validation on mouse samples (fig 5f). Cell Death Dis (2020) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1e
  • western blot; human; loading ...; fig 4a
  • western blot knockout validation; mouse; loading ...; fig 2a
Abcam VDR antibody (Abcam, ab3508) was used in immunohistochemistry - paraffin section on human samples (fig 1e), in western blot on human samples (fig 4a) and in western blot knockout validation on mouse samples (fig 2a). Hepatology (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-6)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 6a
  • immunocytochemistry; mouse; 1:200; loading ...; fig 8b
  • western blot; mouse; 1:200; loading ...; fig 4a
Santa Cruz Biotechnology VDR antibody (Santa Cruz Biotechnology, sc-13133) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 6a), in immunocytochemistry on mouse samples at 1:200 (fig 8b) and in western blot on mouse samples at 1:200 (fig 4a). Sci Rep (2020) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 4a
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 4a). Front Neurol (2020) ncbi
mouse monoclonal (D-6)
  • western blot; mouse; 1:1000; fig 5d
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in western blot on mouse samples at 1:1000 (fig 5d). Nat Commun (2017) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry - frozen section; human; loading ...; fig 2A
  • western blot; human; loading ...; fig 1B
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in immunohistochemistry - frozen section on human samples (fig 2A) and in western blot on human samples (fig 1B). Int J Mol Sci (2017) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry knockout validation; mouse; fig 3B
  • immunohistochemistry - frozen section; mouse; fig 3B
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in immunohistochemistry knockout validation on mouse samples (fig 3B) and in immunohistochemistry - frozen section on mouse samples (fig 3B). PLoS ONE (2016) ncbi
mouse monoclonal (D-6)
  • western blot; human; fig 3
Santa Cruz Biotechnology VDR antibody (santa Cruz, sc-13133) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (D-6)
  • western blot; human; fig 1
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in western blot on human samples (fig 1). Genes Immun (2016) ncbi
mouse monoclonal (D-6)
  • chromatin immunoprecipitation; human
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133 X) was used in chromatin immunoprecipitation on human samples . Biochem Cell Biol (2015) ncbi
mouse monoclonal (D-6)
  • western blot; human; fig 1
Santa Cruz Biotechnology VDR antibody (Santa Cruz Biotechnology, sc-13133) was used in western blot on human samples (fig 1). Oncotarget (2014) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry - paraffin section; human; 1:100
In order to study the role of vitamin D/VDR signaling in tissue barrier function related to psoriasis, Santa Cruz Biotechnology VDR antibody (Santa Cruz Biotechnology, sc-13133) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Eur Acad Dermatol Venereol (2015) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry; mouse; 1:100
  • western blot; mouse; fig 4
Santa Cruz Biotechnology VDR antibody (Santa Cruz Biotechnology, sc13133) was used in immunohistochemistry on mouse samples at 1:100 and in western blot on mouse samples (fig 4). Endocrinology (2014) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry - paraffin section; human; 1:200
In order to assess the effects of a novel Gemini vitamin D analog on breast cancer progression, Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in immunohistochemistry - paraffin section on human samples at 1:200. Cancer Prev Res (Phila) (2014) ncbi
mouse monoclonal (D-6)
  • western blot; human
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in western blot on human samples . J Steroid Biochem Mol Biol (2014) ncbi
mouse monoclonal (D-6)
  • western blot; mouse
Santa Cruz Biotechnology VDR antibody (Santa Cruz Biotechnology, D6) was used in western blot on mouse samples . J Steroid Biochem Mol Biol (2014) ncbi
mouse monoclonal (D-6)
  • western blot; human; 1:500
Santa Cruz Biotechnology VDR antibody (Santa Cruz, sc-13133) was used in western blot on human samples at 1:500. Helicobacter (2014) ncbi
Invitrogen
rat monoclonal (9A7)
  • immunohistochemistry; human; loading ...; fig 1a
In order to measure breast vitamin D receptor expression and correlate its expression with tumor characteristics and patient survival, Invitrogen VDR antibody (ThermoFisher, MA1-710) was used in immunohistochemistry on human samples (fig 1a). Clin Cancer Res (2017) ncbi
rat monoclonal (9A7gamma.E10.E4)
  • western blot; human; 1:1000; fig 1
In order to characterize androgen receptor-targeted and vitamin D therapy for triple-negative breast cancer, Invitrogen VDR antibody (Thermofisher, MA5-14617) was used in western blot on human samples at 1:1000 (fig 1). Breast Cancer Res Treat (2016) ncbi
rat monoclonal (9A7)
  • western blot; human; fig 3
In order to determine the role of diet-derived 25-hydroxyvitamin D3 and suppressionof EGFR mutant non-small cell lung cancer growth in vitro and in vivo, Invitrogen VDR antibody (Thermo Scientific, MA1-710) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
rat monoclonal (9A7)
  • immunohistochemistry - paraffin section; mouse; 1:250; fig 2d
In order to test if vitamin D is protective in the N-nitroso-tris-chloroethylurea mouse model, Invitrogen VDR antibody (Affinity Bio, MA1-710) was used in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig 2d). Cancer Prev Res (Phila) (2015) ncbi
rat monoclonal (9A7)
  • western blot; mouse; fig 6.a,b
In order to study UL97-mediated retinoblastoma phosphorylation, Invitrogen VDR antibody (Thermo Fisher Scientific, 9A7) was used in western blot on mouse samples (fig 6.a,b). J Biol Chem (2015) ncbi
rat monoclonal (9A7)
  • immunohistochemistry - paraffin section; mouse; fig 3
  • western blot; mouse
In order to assess the impact of 1,25(OH)2D3 on the chemopreventive efficacy of erlotinib against head and neck squamous cell carcinomas, Invitrogen VDR antibody (Thermo Fisher Scientific, MA1-710) was used in immunohistochemistry - paraffin section on mouse samples (fig 3) and in western blot on mouse samples . Cancer Prev Res (Phila) (2015) ncbi
rat monoclonal (9A7)
  • chromatin immunoprecipitation; mouse
  • western blot; mouse; 1:500
In order to investigate the relationship between vitamin D and parathyroid hormone signaling during skeletal development, Invitrogen VDR antibody (Affinity Bioreagents, MA1-710) was used in chromatin immunoprecipitation on mouse samples and in western blot on mouse samples at 1:500. J Cell Physiol (2014) ncbi
rat monoclonal (9A7)
  • western blot; human; 1:200
In order to assess the effects of a novel Gemini vitamin D analog on breast cancer progression, Invitrogen VDR antibody (Thermoscientific, MA1-710) was used in western blot on human samples at 1:200. Cancer Prev Res (Phila) (2014) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 4a
Abcam VDR antibody (Abcam, Ab3508) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 4a). World J Gastroenterol (2020) ncbi
domestic rabbit monoclonal (EPR4552)
  • western blot knockout validation; human; loading ...; fig 8b
  • immunohistochemistry knockout validation; mouse; loading ...; fig 5d
  • western blot knockout validation; mouse; loading ...; fig 5f
Abcam VDR antibody (Abcam, ab109234) was used in western blot knockout validation on human samples (fig 8b), in immunohistochemistry knockout validation on mouse samples (fig 5d) and in western blot knockout validation on mouse samples (fig 5f). Cell Death Dis (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1e
  • western blot; human; loading ...; fig 4a
  • western blot knockout validation; mouse; loading ...; fig 2a
Abcam VDR antibody (Abcam, ab3508) was used in immunohistochemistry - paraffin section on human samples (fig 1e), in western blot on human samples (fig 4a) and in western blot knockout validation on mouse samples (fig 2a). Hepatology (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000
In order to examine the impact of vitamin D deficiency on insulin resistance and abnormal glucose homeostasis in obesity, Abcam VDR antibody (Abcam, ab3508) was used in western blot on mouse samples at 1:1000. Mol Nutr Food Res (2016) ncbi
domestic rabbit monoclonal (EPR4552)
  • western blot; human; fig 1
Abcam VDR antibody (Epitomics, 3277-1) was used in western blot on human samples (fig 1). Cell Cycle (2014) ncbi
Bio-Rad
mouse monoclonal (2F4)
  • immunocytochemistry; human; loading ...; fig 1
Bio-Rad VDR antibody (AbD Serotec, MCA3543Z) was used in immunocytochemistry on human samples (fig 1). Int J Mol Sci (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2K6W)
  • western blot; mouse; 1:200; loading ...; fig 8a, 8b
Cell Signaling Technology VDR antibody (Cell Signaling Technology, D2K6W) was used in western blot on mouse samples at 1:200 (fig 8a, 8b). Front Physiol (2020) ncbi
domestic rabbit monoclonal (D2K6W)
  • western blot; mouse; 1:1000; loading ...; fig 7a
Cell Signaling Technology VDR antibody (Cell-Signaling, D2K6W) was used in western blot on mouse samples at 1:1000 (fig 7a). Nutrients (2020) ncbi
domestic rabbit monoclonal (D2K6W)
  • western blot; mouse; 1:200; loading ...; fig 8a, 8b
Cell Signaling Technology VDR antibody (Cell Signaling Technology, D2K6W) was used in western blot on mouse samples at 1:200 (fig 8a, 8b). Mol Med Rep (2020) ncbi
domestic rabbit monoclonal (D2K6W)
  • western blot; human; loading ...; fig 3
Cell Signaling Technology VDR antibody (Cell Signaling, 12550) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
Articles Reviewed
  1. Wang H, Zhang W, Wang Y, Geng X, Wang M, Fan Y, et al. Colonic vitamin D receptor expression is inversely associated with disease activity and jumonji domain-containing 3 in active ulcerative colitis. World J Gastroenterol. 2020;26:7352-7366 pubmed publisher
  2. Curnow A, Gonsalez S, Gogulamudi V, Visniauskas B, Simon E, Gonzalez A, et al. Low Nitric Oxide Bioavailability Increases Renin Production in the Collecting Duct. Front Physiol. 2020;11:559341 pubmed publisher
  3. Anisiewicz A, Kowalski K, Banach J, Łabędź N, Stachowicz Suhs M, Piotrowska A, et al. Vitamin D Metabolite Profile in Cholecalciferol- or Calcitriol-Supplemented Healthy and Mammary Gland Tumor-Bearing Mice. Nutrients. 2020;12: pubmed publisher
  4. Sun H, Jiang Q, Sheng L, Cui K. Downregulation of lncRNA H19 alleviates atherosclerosis through inducing the apoptosis of vascular smooth muscle cells. Mol Med Rep. 2020;22:3095-3102 pubmed publisher
  5. Srikuea R, Hirunsai M, Charoenphandhu N. Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageing. Sci Rep. 2020;10:8239 pubmed publisher
  6. Lee P, Selhorst A, Lampe S, Liu Y, Yang Y, Lovett Racke A. Neuron-Specific Vitamin D Signaling Attenuates Microglia Activation and CNS Autoimmunity. Front Neurol. 2020;11:19 pubmed publisher
  7. Hu Z, Zhang H, Yi B, Yang S, Liu J, Hu J, et al. VDR activation attenuate cisplatin induced AKI by inhibiting ferroptosis. Cell Death Dis. 2020;11:73 pubmed publisher
  8. Wang Y, Du L, Liang X, Meng P, Bi L, Wang Y, et al. Sirtuin 4 Depletion Promotes Hepatocellular Carcinoma Tumorigenesis Through Regulating Adenosine-Monophosphate-Activated Protein Kinase Alpha/Mammalian Target of Rapamycin Axis in Mice. Hepatology. 2018;: pubmed publisher
  9. Zhang X, Hofmann S, Rack B, Harbeck N, Jeschke U, Sixou S. Fluorescence Analysis of Vitamin D Receptor Status of Circulating Tumor Cells (CTCS) in Breast Cancer: From Cell Models to Metastatic Patients. Int J Mol Sci. 2017;18: pubmed publisher
  10. Xu Z, Greenblatt M, Yan G, Feng H, Sun J, Lotinun S, et al. SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. Nat Commun. 2017;8:14570 pubmed publisher
  11. Kempińska Podhorodecka A, Milkiewicz M, Wasik U, Ligocka J, Zawadzki M, Krawczyk M, et al. Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis via the VDR-miRNA155-SOCS1 Pathway. Int J Mol Sci. 2017;18: pubmed publisher
  12. Zhang T, Yin Y, Liu H, Du W, Ren C, Wang L, et al. Generation of VDR Knock-Out Mice via Zygote Injection of CRISPR/Cas9 System. PLoS ONE. 2016;11:e0163551 pubmed publisher
  13. Al Azhri J, Zhang Y, Bshara W, Zirpoli G, McCann S, Khoury T, et al. Tumor Expression of Vitamin D Receptor and Breast Cancer Histopathological Characteristics and Prognosis. Clin Cancer Res. 2017;23:97-103 pubmed publisher
  14. Thakkar A, Wang B, Picon Ruiz M, Buchwald P, Ince T. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer. Breast Cancer Res Treat. 2016;157:77-90 pubmed publisher
  15. Reynolds J, Haque S, Williamson K, Ray D, Alexander M, Bruce I. Vitamin D improves endothelial dysfunction and restores myeloid angiogenic cell function via reduced CXCL-10 expression in systemic lupus erythematosus. Sci Rep. 2016;6:22341 pubmed publisher
  16. Gari H, Gearheart C, Fosmire S, Degala G, Fan Z, Torkko K, et al. Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers. Oncotarget. 2016;7:15757-71 pubmed publisher
  17. Berge T, Leikfoss I, Brorson I, Bos S, Page C, Gustavsen M, et al. The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells. Genes Immun. 2016;17:118-27 pubmed publisher
  18. Verone Boyle A, Shoemaker S, Attwood K, Morrison C, Makowski A, Battaglia S, et al. Diet-derived 25-hydroxyvitamin D3 activates vitamin D receptor target gene expression and suppresses EGFR mutant non-small cell lung cancer growth in vitro and in vivo. Oncotarget. 2016;7:995-1013 pubmed publisher
  19. Borges C, Salles A, Bringhenti I, Souza Mello V, Mandarim de Lacerda C, Aguila M. Adverse effects of vitamin D deficiency on the Pi3k/Akt pathway and pancreatic islet morphology in diet-induced obese mice. Mol Nutr Food Res. 2016;60:346-57 pubmed publisher
  20. Mazzilli S, Hershberger P, Reid M, Bogner P, Atwood K, Trump D, et al. Vitamin D Repletion Reduces the Progression of Premalignant Squamous Lesions in the NTCU Lung Squamous Cell Carcinoma Mouse Model. Cancer Prev Res (Phila). 2015;8:895-904 pubmed publisher
  21. Iwahori S, Hakki M, Chou S, Kalejta R. Molecular Determinants for the Inactivation of the Retinoblastoma Tumor Suppressor by the Viral Cyclin-dependent Kinase UL97. J Biol Chem. 2015;290:19666-80 pubmed publisher
  22. Bothwell K, Shaurova T, Merzianu M, Suresh A, Kuriakose M, Johnson C, et al. Impact of Short-term 1,25-Dihydroxyvitamin D3 on the Chemopreventive Efficacy of Erlotinib against Oral Cancer. Cancer Prev Res (Phila). 2015;8:765-76 pubmed publisher
  23. Bhattacharjee V, Zhou Y, Yen T. A synthetic lethal screen identifies the Vitamin D receptor as a novel gemcitabine sensitizer in pancreatic cancer cells. Cell Cycle. 2014;13:3839-56 pubmed publisher
  24. Cázares Ordoñez V, González Duarte R, Díaz L, Ishizawa M, Uno S, Ortíz V, et al. A cis-acting element in the promoter of human ether à go-go 1 potassium channel gene mediates repression by calcitriol in human cervical cancer cells. Biochem Cell Biol. 2015;93:94-101 pubmed publisher
  25. Pickholtz I, Saadyan S, Keshet G, Wang V, Cohen R, Bouwman P, et al. Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells. Oncotarget. 2014;5:11827-46 pubmed
  26. Visconti B, Paolino G, Carotti S, Pendolino A, Morini S, Richetta A, et al. Immunohistochemical expression of VDR is associated with reduced integrity of tight junction complex in psoriatic skin. J Eur Acad Dermatol Venereol. 2015;29:2038-42 pubmed publisher
  27. Girgis C, Mokbel N, Cha K, Houweling P, Abboud M, Fraser D, et al. The vitamin D receptor (VDR) is expressed in skeletal muscle of male mice and modulates 25-hydroxyvitamin D (25OHD) uptake in myofibers. Endocrinology. 2014;155:3227-37 pubmed publisher
  28. Bach F, Rutten K, Hendriks K, Riemers F, Cornelissen P, de Bruin A, et al. The paracrine feedback loop between vitamin D? (1,25(OH)?D?) and PTHrP in prehypertrophic chondrocytes. J Cell Physiol. 2014;229:1999-2014 pubmed publisher
  29. Wahler J, So J, Kim Y, Liu F, Maehr H, Uskokovic M, et al. Inhibition of the transition of ductal carcinoma in situ to invasive ductal carcinoma by a Gemini vitamin D analog. Cancer Prev Res (Phila). 2014;7:617-26 pubmed publisher
  30. Zhong W, Gu B, Gu Y, Groome L, Sun J, Wang Y. Activation of vitamin D receptor promotes VEGF and CuZn-SOD expression in endothelial cells. J Steroid Biochem Mol Biol. 2014;140:56-62 pubmed publisher
  31. LaPorta E, Welsh J. Modeling vitamin D actions in triple negative/basal-like breast cancer. J Steroid Biochem Mol Biol. 2014;144 Pt A:65-73 pubmed publisher
  32. Guo L, Chen W, Zhu H, Chen Y, Wan X, Yang N, et al. Helicobacter pylori induces increased expression of the vitamin d receptor in immune responses. Helicobacter. 2014;19:37-47 pubmed publisher