This is a Validated Antibody Database (VAD) review about human USP8, based on 4 published articles (read how Labome selects the articles), using USP8 antibody in all methods. It is aimed to help Labome visitors find the most suited USP8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
USP8 synonym: HumORF8; PITA4; SPG59; UBPY

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (E-1)
  • western blot knockout validation; human; 1:1000; loading ...; fig s4e
  • immunohistochemistry - paraffin section; human; 1:100; fig 1q
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1h
Santa Cruz Biotechnology USP8 antibody (Santa Cruz, sc-376130) was used in western blot knockout validation on human samples at 1:1000 (fig s4e), in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1q) and in western blot knockout validation on mouse samples at 1:1000 (fig 1h). Nat Commun (2022) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D18F6)
  • western blot knockout validation; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology USP8 antibody (Cell Signaling, 11832) was used in western blot knockout validation on human samples at 1:1000 (fig 2b). Cell Rep (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-1)
  • western blot knockout validation; human; 1:1000; loading ...; fig s4e
  • immunohistochemistry - paraffin section; human; 1:100; fig 1q
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1h
Santa Cruz Biotechnology USP8 antibody (Santa Cruz, sc-376130) was used in western blot knockout validation on human samples at 1:1000 (fig s4e), in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1q) and in western blot knockout validation on mouse samples at 1:1000 (fig 1h). Nat Commun (2022) ncbi
mouse monoclonal (F-3)
  • immunohistochemistry - frozen section; mouse; 1:50
  • immunocytochemistry; mouse; 1:50
In order to study STAM2 in the nervous system, Santa Cruz Biotechnology USP8 antibody (Santa Cruz, sc-365481) was used in immunohistochemistry - frozen section on mouse samples at 1:50 and in immunocytochemistry on mouse samples at 1:50. Mol Cell Neurosci (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D18F6)
  • western blot; human; 1:1000; loading ...; fig 3d
Cell Signaling Technology USP8 antibody (Cell Signaling Technology, 11832) was used in western blot on human samples at 1:1000 (fig 3d). Oncogenesis (2021) ncbi
domestic rabbit monoclonal (D18F6)
  • western blot knockout validation; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology USP8 antibody (Cell Signaling, 11832) was used in western blot knockout validation on human samples at 1:1000 (fig 2b). Cell Rep (2017) ncbi
Articles Reviewed
  1. Xiong W, Gao X, Zhang T, Jiang B, Hu M, Bu X, et al. USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy. Nat Commun. 2022;13:1700 pubmed publisher
  2. Wang Y, Liu I, Chen K, Wu H. NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck. Oncogenesis. 2021;10:59 pubmed publisher
  3. Goodwin J, Dowdle W, Dejesus R, Wang Z, Bergman P, Kobylarz M, et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep. 2017;20:2341-2356 pubmed publisher
  4. Kapuralin K, Ćurlin M, Mitrečić D, Kosi N, Schwarzer C, Glavan G, et al. STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons. Mol Cell Neurosci. 2015;67:104-15 pubmed publisher