This is a Validated Antibody Database (VAD) review about human UQCRC1, based on 31 published articles (read how Labome selects the articles), using UQCRC1 antibody in all methods. It is aimed to help Labome visitors find the most suited UQCRC1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
UQCRC1 synonym: D3S3191; QCR1; UQCR1

Invitrogen
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; 1:2000; fig s7e
Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on mouse samples at 1:2000 (fig s7e). Nat Commun (2020) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; 1:2000; fig s7e
Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on mouse samples at 1:2000 (fig s7e). Cancer Sci (2020) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; loading ...; fig s3d
Invitrogen UQCRC1 antibody (Thermo Fisher, A21362) was used in western blot on mouse samples (fig s3d). Sci Adv (2019) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; rat; 1:1000; loading ...; fig 6e
In order to evaluate the mitochondrial dynamics of the cerebral vasculature of 14-week-old Zucker diabetic fatty obese rats with early type 2 diabetes, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on rat samples at 1:1000 (fig 6e). J Vasc Res (2017) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; 1:2000; loading ...; fig s6c
In order to demonstrate that Fat1 cadherin represses mitochondrial respiration that regulates vascular smooth muscle cell proliferation after arterial injury, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on mouse samples at 1:2000 (fig s6c). Nature (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; loading ...
In order to investigate the role of Complex I accessory subunits, Invitrogen UQCRC1 antibody (ThermoFisher, 16D10AD9AH5) was used in western blot on human samples . Nature (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; loading ...; fig 6a
In order to test if electron transport chain disruption eliminates Her2-high disease, Invitrogen UQCRC1 antibody (Life Technologies, 459140) was used in western blot on human samples (fig 6a). Antioxid Redox Signal (2017) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; loading ...; fig 2b
In order to demonstrate that miR-181a inhibits mitophagy, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on human samples (fig 2b). Oncotarget (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; 1:20,000; fig s6
In order to elucidate regulation of brown and beige adipocyte function via ASK1 signaling, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on mouse samples at 1:20,000 (fig s6). Nat Commun (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; rat; 1:1000; fig 6
In order to study cerebral vasculature mitochondrial function in insulin-resistant Zucker obese rats, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on rat samples at 1:1000 (fig 6). Am J Physiol Heart Circ Physiol (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; fig 7
In order to analyze GTPBP3 defective expression in AMPK-mediated responses, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on human samples (fig 7). PLoS ONE (2015) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; rat; 1:1000
In order to test if mitochondrial energetics of large cerebral arteries are sex dependent, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on rat samples at 1:1000. Am J Physiol Heart Circ Physiol (2015) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse
In order to test the requirement of AMP-activated protein kinase for exercise training-induced increases in skeletal muscle abundance of mitochondrial proteins, Invitrogen UQCRC1 antibody (Invitrogen, #459140) was used in western blot on mouse samples . Front Physiol (2015) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse
In order to investigate the role of FoxO1 during adipocyte differentiation and adipogenesis, Invitrogen UQCRC1 antibody (Invitrogen, A21362) was used in western blot on mouse samples . Cell Cycle (2014) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; rat; 1:5000
In order to investigate the role of mitochondria in manganese-induced Parkinsonism, Invitrogen UQCRC1 antibody (Molecular Probes, 459140) was used in western blot on rat samples at 1:5000. PLoS ONE (2014) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; fig 1
In order to study NF-kappaB signaling during in lymphoid development, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in western blot on mouse samples (fig 1). J Cell Biol (2012) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; rat; fig 5
In order to investigate the molecular mechanisms involved in manganese neurotoxicity, Invitrogen UQCRC1 antibody (Life Technologies, 459140) was used in western blot on rat samples (fig 5). Neurochem Int (2011) ncbi
mouse monoclonal (16D10AD9AH5)
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 1
In order to investigate the effects of mitochondrial DNA damage on hippocampal neurons, Invitrogen UQCRC1 antibody (Invitrogen, 459140) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 1). DNA Repair (Amst) (2011) ncbi
Abcam
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; loading ...; fig e1d
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples (fig e1d). Nat Immunol (2020) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; loading ...; fig 3c
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on human samples (fig 3c). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig e4c
Abcam UQCRC1 antibody (Abcam, ab118687) was used in western blot on human samples (fig e4c). Nature (2019) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; loading ...
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on human samples . elife (2019) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; loading ...; fig 1e
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples (fig 1e). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; loading ...; fig 3b
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples (fig 3b). Mol Biol Cell (2017) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; 1:5000; loading ...; fig 1b
In order to explore how bacterial infections alter the mitochondrial electron-transport chain in macrophages, Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples at 1:5000 (fig 1b). Nat Immunol (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; 1:20,000; fig 2
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples at 1:20,000 (fig 2). Oxid Med Cell Longev (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; fig s2
  • western blot; mouse; fig s2
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on human samples (fig s2) and in western blot on mouse samples (fig s2). Biochim Biophys Acta (2016) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; fig 7
In order to study metalloprotease OMA1 and how it fine-tunes mitochondrial bioenergetic function and respiratory supercomplex stability, Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples (fig 7). Sci Rep (2015) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse; fig 6
In order to compare two mouse models with a genetic modification in the Coq9 gene, Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples (fig 6). EMBO Mol Med (2015) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; mouse
  • western blot; human
  • western blot; rat
Abcam UQCRC1 antibody (Abcam, ab110252) was used in western blot on mouse samples , in western blot on human samples and in western blot on rat samples . PLoS ONE (2013) ncbi
mouse monoclonal (16D10AD9AH5)
  • western blot; human; 1:1000
Abcam UQCRC1 antibody (Abcam, AB110252) was used in western blot on human samples at 1:1000. Mitochondrion (2013) ncbi
Articles Reviewed
  1. Yamamuro T, Kawabata T, Fukuhara A, Saita S, Nakamura S, Takeshita H, et al. Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. Nat Commun. 2020;11:4150 pubmed publisher
  2. Zhou H, Wang H, Yu M, Schugar R, Qian W, Tang F, et al. IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. Nat Immunol. 2020;21:1219-1231 pubmed publisher
  3. Kyo S, Sato S, Nakayama K. Cancer-associated mutations in normal human endometrium: Surprise or expected?. Cancer Sci. 2020;111:3458-3467 pubmed publisher
  4. Dalton W, Helmenstine E, Walsh N, Gondek L, Kelkar D, Read A, et al. Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation. J Clin Invest. 2019;130:4708-4723 pubmed publisher
  5. Filograna R, Koolmeister C, Upadhyay M, Pajak A, Clemente P, Wibom R, et al. Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse. Sci Adv. 2019;5:eaav9824 pubmed publisher
  6. Lee J, Yesilkanal A, Wynne J, Frankenberger C, Liu J, Yan J, et al. Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. 2019;568:254-258 pubmed publisher
  7. Yambire K, Fernández Mosquera L, Steinfeld R, Mühle C, Ikonen E, Milosevic I, et al. Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases. elife. 2019;8: pubmed publisher
  8. Kazak L, Chouchani E, Stavrovskaya I, Lu G, Jedrychowski M, Egan D, et al. UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction. Proc Natl Acad Sci U S A. 2017;114:7981-7986 pubmed publisher
  9. Merdzo I, Rutkai I, Sure V, McNulty C, Katakam P, Busija D. Impaired Mitochondrial Respiration in Large Cerebral Arteries of Rats with Type 2 Diabetes. J Vasc Res. 2017;54:1-12 pubmed publisher
  10. Patrinostro X, O Rourke A, Chamberlain C, Moriarity B, Perrin B, Ervasti J. Relative importance of ?cyto- and ?cyto-actin in primary mouse embryonic fibroblasts. Mol Biol Cell. 2017;28:771-782 pubmed publisher
  11. Cao L, Riascos Bernal D, Chinnasamy P, Dunaway C, Hou R, Pujato M, et al. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016;539:575-578 pubmed publisher
  12. Stroud D, Surgenor E, Formosa L, Reljic B, Frazier A, Dibley M, et al. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Nature. 2016;538:123-126 pubmed publisher
  13. Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork Geleta A, Blecha J, Endaya B, et al. Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer. Antioxid Redox Signal. 2017;26:84-103 pubmed publisher
  14. Garaude J, Acin Perez R, Martínez Cano S, Enamorado M, Ugolini M, Nistal Villán E, et al. Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense. Nat Immunol. 2016;17:1037-1045 pubmed publisher
  15. Cheng M, Liu L, Lao Y, Liao W, Liao M, Luo X, et al. MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget. 2016;7:42274-42287 pubmed publisher
  16. Chen Y, Pandiri I, Joe Y, Kim H, Kim S, Park J, et al. Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis. Oxid Med Cell Longev. 2016;2016:3949813 pubmed publisher
  17. Hattori K, Naguro I, Okabe K, Funatsu T, Furutani S, Takeda K, et al. ASK1 signalling regulates brown and beige adipocyte function. Nat Commun. 2016;7:11158 pubmed publisher
  18. Merdzo I, Rutkai I, Tokés T, Sure V, Katakam P, Busija D. The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese rats. Am J Physiol Heart Circ Physiol. 2016;310:H830-8 pubmed publisher
  19. Kovarova N, Pecina P, Nůsková H, Vrbacky M, Zeviani M, Mracek T, et al. Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects. Biochim Biophys Acta. 2016;1862:705-715 pubmed publisher
  20. Martínez Zamora A, Meseguer S, Esteve J, Villarroya M, Aguado C, Enríquez J, et al. Defective Expression of the Mitochondrial-tRNA Modifying Enzyme GTPBP3 Triggers AMPK-Mediated Adaptive Responses Involving Complex I Assembly Factors, Uncoupling Protein 2, and the Mitochondrial Pyruvate Carrier. PLoS ONE. 2015;10:e0144273 pubmed publisher
  21. Bohovych I, Fernandez M, Rahn J, Stackley K, Bestman J, Anandhan A, et al. Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability. Sci Rep. 2015;5:13989 pubmed publisher
  22. Rutkai I, Dutta S, Katakam P, Busija D. Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries. Am J Physiol Heart Circ Physiol. 2015;309:H1490-500 pubmed publisher
  23. Brandauer J, Andersen M, Kellezi H, Risis S, Frøsig C, Vienberg S, et al. AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD. Front Physiol. 2015;6:85 pubmed publisher
  24. Luna Sánchez M, Díaz Casado E, Barca E, Tejada M, Montilla García Ã, Cobos E, et al. The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene. EMBO Mol Med. 2015;7:670-87 pubmed publisher
  25. Zou P, Liu L, Zheng L, Liu L, Stoneman R, Cho A, et al. Targeting FoxO1 with AS1842856 suppresses adipogenesis. Cell Cycle. 2014;13:3759-67 pubmed publisher
  26. Alaimo A, Gorojod R, Beauquis J, Muñoz M, Saravia F, Kotler M. Deregulation of mitochondria-shaping proteins Opa-1 and Drp-1 in manganese-induced apoptosis. PLoS ONE. 2014;9:e91848 pubmed publisher
  27. Kovarova N, Mracek T, Nůsková H, Holzerová E, Vrbacky M, Pecina P, et al. High molecular weight forms of mammalian respiratory chain complex II. PLoS ONE. 2013;8:e71869 pubmed publisher
  28. Murad N, Cullen J, McKenzie M, Ryan M, Thorburn D, Gueven N, et al. Mitochondrial dysfunction in a novel form of autosomal recessive ataxia. Mitochondrion. 2013;13:235-45 pubmed publisher
  29. Bakkar N, Ladner K, Canan B, Liyanarachchi S, Bal N, Pant M, et al. IKK? and alternative NF-?B regulate PGC-1? to promote oxidative muscle metabolism. J Cell Biol. 2012;196:497-511 pubmed publisher
  30. Alaimo A, Gorojod R, Kotler M. The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells. Neurochem Int. 2011;59:297-308 pubmed publisher
  31. Lauritzen K, Cheng C, Wiksen H, Bergersen L, Klungland A. Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses. DNA Repair (Amst). 2011;10:639-53 pubmed publisher