This is a Validated Antibody Database (VAD) review about human UBTF, based on 23 published articles (read how Labome selects the articles), using UBTF antibody in all methods. It is aimed to help Labome visitors find the most suited UBTF antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
UBTF synonym: CONDBA; NOR-90; UBF; UBF-1; UBF1; UBF2; nucleolar transcription factor 1; 90-kDa nucleolus organizer region autoantigen; autoantigen NOR-90; upstream binding transcription factor, RNA polymerase I

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (F-9)
  • immunocytochemistry knockout validation; chicken; 1:250; fig 6
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in immunocytochemistry knockout validation on chicken samples at 1:250 (fig 6). Nat Commun (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-9)
  • immunocytochemistry; human; loading ...; fig 3g
  • western blot; human; loading ...; fig 3c
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, F-9/sc-13125) was used in immunocytochemistry on human samples (fig 3g) and in western blot on human samples (fig 3c). Genes Dev (2018) ncbi
mouse monoclonal (F-9)
  • western blot; human; 1:500; loading ...; fig 1a
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology Inc, sc-13125) was used in western blot on human samples at 1:500 (fig 1a). Nucleic Acids Res (2018) ncbi
mouse monoclonal (F-9)
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology UBTF antibody (SantaCruz, sc-13125) was used in western blot on human samples (fig 3a). Am J Hum Genet (2017) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; 1:150; loading ...; fig 3b
In order to report the interactome of all dipeptide repeat proteins, Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in immunocytochemistry on human samples at 1:150 (fig 3b). Cell (2016) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; 1:250; fig 4
In order to investigate the connection between calorie restriction and magnesium, Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in immunocytochemistry on human samples at 1:250 (fig 4). Nucleic Acids Res (2016) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; 1:500; fig s4
In order to describe a novel irreversible DNA-damage response in antephase, Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in immunocytochemistry on human samples at 1:500 (fig s4). Nat Commun (2016) ncbi
mouse monoclonal (F-9)
  • western blot; rat; loading ...; fig 5b
Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in western blot on rat samples (fig 5b). Sci Rep (2016) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; 1:100; loading ...; fig s2b
  • western blot; human; 1:500; loading ...; fig 3d
In order to research the Wnt5a/DVL1 signaling pathway and its role on ribosomal DNA transcription, Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotech, SC-13125) was used in immunocytochemistry on human samples at 1:100 (fig s2b) and in western blot on human samples at 1:500 (fig 3d). PLoS Genet (2016) ncbi
mouse monoclonal (F-9)
  • western blot; human; fig s2b
Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in western blot on human samples (fig s2b). Nat Commun (2016) ncbi
mouse monoclonal (F-9)
  • western blot; human; fig 5A
Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in western blot on human samples (fig 5A). Sci Rep (2015) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry knockout validation; chicken; 1:250; fig 6
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in immunocytochemistry knockout validation on chicken samples at 1:250 (fig 6). Nat Commun (2015) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; fig 7a
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in immunocytochemistry on human samples (fig 7a). Mol Cell Biol (2015) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; loading ...; fig 2e
Santa Cruz Biotechnology UBTF antibody (SantaCruz, sc-13125) was used in immunocytochemistry on human samples (fig 2e). PLoS Genet (2015) ncbi
mouse monoclonal (F-9)
  • western blot; mouse; fig 2
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in western blot on mouse samples (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in immunocytochemistry on human samples . Nucleus (2015) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; fig 1
Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in immunocytochemistry on human samples (fig 1). Nucleic Acids Res (2015) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in immunocytochemistry on human samples . J Neurochem (2014) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; 1:300; fig s5
Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in immunocytochemistry on human samples at 1:300 (fig s5). Nat Cell Biol (2014) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; fig 2
Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in immunocytochemistry on human samples (fig 2). Mol Biol Cell (2014) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; Lagranja shrew
Santa Cruz Biotechnology UBTF antibody (Santa Cruz, sc-13125) was used in immunocytochemistry on Lagranja shrew samples . Mol Cell Biol (2014) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human; 1:50
  • western blot; human; 1:1000
In order to determine the cellular function of Lyar, Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in immunocytochemistry on human samples at 1:50 and in western blot on human samples at 1:1000. Genes Cells (2014) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, SC-13125) was used in immunocytochemistry on human samples . Biochem J (2013) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry; human
  • western blot; human
Santa Cruz Biotechnology UBTF antibody (Santa Cruz Biotechnology, sc-13125) was used in immunocytochemistry on human samples and in western blot on human samples . J Biol Chem (2013) ncbi
Articles Reviewed
  1. Lafita Navarro M, Kim M, Borenstein Auerbach N, Venkateswaran N, Hao Y, Ray R, et al. The aryl hydrocarbon receptor regulates nucleolar activity and protein synthesis in MYC-expressing cells. Genes Dev. 2018;32:1303-1308 pubmed publisher
  2. Chen J, Lobb I, Morin P, Novo S, Simpson J, Kennerknecht K, et al. Identification of a novel TIF-IA-NF-κB nucleolar stress response pathway. Nucleic Acids Res. 2018;46:6188-6205 pubmed publisher
  3. Edvardson S, Nicolae C, Agrawal P, Mignot C, Payne K, Prasad A, et al. Heterozygous De Novo UBTF Gain-of-Function Variant Is Associated with Neurodegeneration in Childhood. Am J Hum Genet. 2017;101:267-273 pubmed publisher
  4. Lee K, Zhang P, Kim H, Mitrea D, Sarkar M, Freibaum B, et al. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell. 2016;167:774-788.e17 pubmed publisher
  5. Abraham K, Chan J, Salvi J, Ho B, Hall A, Vidya E, et al. Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids. Nucleic Acids Res. 2016;44:8870-8884 pubmed
  6. Feringa F, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, et al. Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. Nat Commun. 2016;7:12618 pubmed publisher
  7. Ogasawara R, Fujita S, Hornberger T, Kitaoka Y, Makanae Y, Nakazato K, et al. The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise. Sci Rep. 2016;6:31142 pubmed publisher
  8. Dass R, Sarshad A, Carson B, Feenstra J, Kaur A, Obrdlik A, et al. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I. PLoS Genet. 2016;12:e1006217 pubmed publisher
  9. Chen S, Blank M, Iyer A, Huang B, Wang L, Grummt I, et al. SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing. Nat Commun. 2016;7:10734 pubmed publisher
  10. Yu F, Shen X, Fan L, Yu Z. Analysis of histone modifications at human ribosomal DNA in liver cancer cell. Sci Rep. 2015;5:18100 pubmed publisher
  11. Nielsen C, Huttner D, Bizard A, Hirano S, Li T, Palmai Pallag T, et al. PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis. Nat Commun. 2015;6:8962 pubmed publisher
  12. Wandrey F, Montellese C, Koos K, Badertscher L, Bammert L, Cook A, et al. The NF45/NF90 Heterodimer Contributes to the Biogenesis of 60S Ribosomal Subunits and Influences Nucleolar Morphology. Mol Cell Biol. 2015;35:3491-503 pubmed publisher
  13. Voit R, Seiler J, Grummt I. Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis. PLoS Genet. 2015;11:e1005246 pubmed publisher
  14. Ide S, Déjardin J. End-targeting proteomics of isolated chromatin segments of a mammalian ribosomal RNA gene promoter. Nat Commun. 2015;6:6674 pubmed publisher
  15. Ehm P, Nalaskowski M, Wundenberg T, Jücker M. The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies. Nucleus. 2015;6:154-64 pubmed publisher
  16. Schertzer M, Jouravleva K, Perderiset M, Dingli F, Loew D, Le Guen T, et al. Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA. Nucleic Acids Res. 2015;43:1834-47 pubmed publisher
  17. Khalouei S, Chow A, Brown I. Localization of heat shock protein HSPA6 (HSP70B') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. J Neurochem. 2014;131:743-54 pubmed publisher
  18. Larsen D, Hari F, Clapperton J, Gwerder M, Gutsche K, Altmeyer M, et al. The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage. Nat Cell Biol. 2014;16:792-803 pubmed publisher
  19. Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed publisher
  20. Zhdanova N, Draskovic I, Minina J, Karamysheva T, Novo C, Liu W, et al. Recombinogenic telomeres in diploid Sorex granarius (Soricidae, Eulipotyphla) fibroblast cells. Mol Cell Biol. 2014;34:2786-99 pubmed publisher
  21. Miyazawa N, Yoshikawa H, Magae S, Ishikawa H, Izumikawa K, Terukina G, et al. Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA. Genes Cells. 2014;19:273-86 pubmed publisher
  22. Wolf A, Mantri M, Heim A, Müller U, Fichter E, Mackeen M, et al. The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization. Biochem J. 2013;453:357-70 pubmed publisher
  23. Wang J, Leung J, Gong Z, Feng L, Shi X, Chen J. PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. J Biol Chem. 2013;288:3174-83 pubmed publisher