This is a Validated Antibody Database (VAD) review about human UBR1, based on 2 published articles (read how Labome selects the articles), using UBR1 antibody in all methods. It is aimed to help Labome visitors find the most suited UBR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
UBR1 synonym: JBS; E3 ubiquitin-protein ligase UBR1; E3a ligase; N-recognin-1; RING-type E3 ubiquitin transferase UBR1; ubiquitin ligase E3 alpha-I; ubiquitin-protein ligase E3-alpha; ubiquitin-protein ligase E3-alpha-1; ubiquitin-protein ligase E3-alpha-I

Abcam
rabbit polyclonal
  • western blot; human
In order to show that UBR1 regulates MGMT homeostasis and DNA repair of alkylated DNA adducts in cells, Abcam UBR1 antibody (Abcam, ab42420) was used in western blot on human samples . Cancer Res (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (24-Z)
  • western blot; human
Santa Cruz Biotechnology UBR1 antibody (Santa Cruz Biotechnology, sc-100626) was used in western blot on human samples . Oncotarget (2014) ncbi
Articles Reviewed
  1. Leng S, Wu G, Collins L, Thomas C, Tellez C, Jauregui A, et al. Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung. Cancer Res. 2015;75:3108-17 pubmed publisher
  2. Eldeeb M, Fahlman R. The anti-apoptotic form of tyrosine kinase Lyn that is generated by proteolysis is degraded by the N-end rule pathway. Oncotarget. 2014;5:2714-22 pubmed