This is a Validated Antibody Database (VAD) review about human UBE4B, based on 4 published articles (read how Labome selects the articles), using UBE4B antibody in all methods. It is aimed to help Labome visitors find the most suited UBE4B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
UBE4B synonym: HDNB1; UBOX3; UFD2; UFD2A; ubiquitin conjugation factor E4 B; RING-type E3 ubiquitin transferase E4 B; UFD2A-III/UBE4B-III splice isoform; homologous to yeast UFD2; homozygously deleted in neuroblastoma-1; ubiquitin-fusion degradation protein 2; ubiquitination factor E4B (UFD2 homolog, yeast)

Abcam
rabbit monoclonal (EPR7471)
  • western blot; human; fig 9a
In order to assess inhibition of the SUMOylation of VCP that leads to impaired stress response by pathogenic mutations in the valosin-containing protein/p97(VCP) N-domain, Abcam UBE4B antibody (Epitomics, 5550) was used in western blot on human samples (fig 9a). J Biol Chem (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:400; fig 5
  • western blot; human; 1:1000; fig 7
Abcam UBE4B antibody (Abcam, ab97697) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 5) and in western blot on human samples at 1:1000 (fig 7). Genes Cancer (2016) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:2000
Proteintech Group UBE4B antibody (Proteintech, 18148-1-AP) was used in western blot on human samples at 1:2000. Mol Carcinog (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (RQ-5)
  • western blot; human; fig 1a
In order to study the effect of UBE4B on phosphorylated p53 at serines 15 and 392, Santa Cruz Biotechnology UBE4B antibody (Santa Cruz, RQ-5) was used in western blot on human samples (fig 1a). Oncotarget (2016) ncbi
Articles Reviewed
  1. Wang T, Xu W, Qin M, Yang Y, Bao P, Shen F, et al. Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response. J Biol Chem. 2016;291:14373-84 pubmed publisher
  2. Woodfield S, Guo R, Liu Y, Major A, Hollingsworth E, Indiviglio S, et al. Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B. Genes Cancer. 2016;7:13-26 pubmed
  3. Du C, Wu H, Leng R. UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation. Oncotarget. 2016;7:2823-36 pubmed publisher
  4. Zhang X, Pan Q, Pan K, Weng D, Wang Q, Zhao J, et al. Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma. Mol Carcinog. 2016;55:64-76 pubmed publisher