This is a Validated Antibody Database (VAD) review about human UBE3A, based on 9 published articles (read how Labome selects the articles), using UBE3A antibody in all methods. It is aimed to help Labome visitors find the most suited UBE3A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
UBE3A synonym: ANCR; AS; E6-AP; EPVE6AP; HPVE6A

Knockout validation
MilliporeSigma
mouse monoclonal (3.00E+05)
  • immunohistochemistry knockout validation; mouse; 1:10,000; loading ...; fig 1e
  • immunohistochemistry - free floating section; mouse; 1:10,000; loading ...; fig 1a
MilliporeSigma UBE3A antibody (Sigma-Aldrich, SAB1404508) was used in immunohistochemistry knockout validation on mouse samples at 1:10,000 (fig 1e) and in immunohistochemistry - free floating section on mouse samples at 1:10,000 (fig 1a). J Comp Neurol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-4)
  • western blot; mouse; loading ...; fig 6a
Santa Cruz Biotechnology UBE3A antibody (Santa Cruz Biotechnology Inc, sc-166689) was used in western blot on mouse samples (fig 6a). Mol Autism (2018) ncbi
MilliporeSigma
mouse monoclonal (3.00E+05)
  • immunohistochemistry - frozen section; mouse; 1:300; loading ...; fig 4b
MilliporeSigma UBE3A antibody (Sigma, SAB1404508) was used in immunohistochemistry - frozen section on mouse samples at 1:300 (fig 4b). elife (2019) ncbi
mouse monoclonal (3.00E+05)
  • immunohistochemistry knockout validation; mouse; 1:10,000; loading ...; fig 1e
  • immunohistochemistry - free floating section; mouse; 1:10,000; loading ...; fig 1a
MilliporeSigma UBE3A antibody (Sigma-Aldrich, SAB1404508) was used in immunohistochemistry knockout validation on mouse samples at 1:10,000 (fig 1e) and in immunohistochemistry - free floating section on mouse samples at 1:10,000 (fig 1a). J Comp Neurol (2017) ncbi
mouse monoclonal (3.00E+05)
  • immunohistochemistry - frozen section; mouse; 1:1000
In order to study Ube3a imprinting in a mouse model of Angelman syndrome, MilliporeSigma UBE3A antibody (Sigma, SAB1404508) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. Sci Rep (2016) ncbi
mouse monoclonal (3.00E+05)
  • immunohistochemistry - free floating section; mouse; 1:750
  • western blot; mouse; 1:1000
MilliporeSigma UBE3A antibody (Sigma-Aldrich, SAB1404508) was used in immunohistochemistry - free floating section on mouse samples at 1:750 and in western blot on mouse samples at 1:1000. J Comp Neurol (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D10D3)
  • western blot; mouse; loading ...; fig ex2d
Cell Signaling Technology UBE3A antibody (Cell Signaling, 7526) was used in western blot on mouse samples (fig ex2d). Nature (2017) ncbi
BD Biosciences
mouse monoclonal (13/UBE3A)
  • western blot; human; loading ...; fig 3d
BD Biosciences UBE3A antibody (BD Biosciences, 611416) was used in western blot on human samples (fig 3d). Science (2017) ncbi
mouse monoclonal (13/UBE3A)
  • western blot; mouse; 1:1000; loading ...; fig 5a
In order to elucidate the role of HAP40 in Huntington's disease, BD Biosciences UBE3A antibody (BD Biosciences, 611416) was used in western blot on mouse samples at 1:1000 (fig 5a). Mol Neurobiol (2017) ncbi
mouse monoclonal (13/UBE3A)
  • western blot; mouse; 1:500; fig 1
BD Biosciences UBE3A antibody (BD Biosciences, 611416) was used in western blot on mouse samples at 1:500 (fig 1). Nature (2015) ncbi
Articles Reviewed
  1. Stedehouder J, Brizee D, Slotman J, Pascual Garcia M, Leyrer M, Bouwen B, et al. Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex. elife. 2019;8: pubmed publisher
  2. Brown E, Lautz J, Davis T, Gniffke E, VanSchoiack A, Neier S, et al. Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models. Mol Autism. 2018;9:48 pubmed publisher
  3. Takahashi Y, Wu J, Suzuki K, Martínez Redondo P, Li M, Liao H, et al. Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells. Science. 2017;356:503-508 pubmed publisher
  4. Krishnan V, Stoppel D, Nong Y, Johnson M, Nadler M, Ozkaynak E, et al. Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1. Nature. 2017;543:507-512 pubmed publisher
  5. Huang Z, Her L. The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity. Mol Neurobiol. 2017;54:7382-7400 pubmed publisher
  6. Burette A, Judson M, Burette S, Phend K, Philpot B, Weinberg R. Subcellular organization of UBE3A in neurons. J Comp Neurol. 2017;525:233-251 pubmed publisher
  7. Jones K, Han J, Debruyne J, Philpot B. Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice. Sci Rep. 2016;6:28238 pubmed publisher
  8. Meng L, Ward A, Chun S, Bennett C, Beaudet A, Rigo F. Towards a therapy for Angelman syndrome by targeting a long non-coding RNA. Nature. 2015;518:409-12 pubmed publisher
  9. Judson M, Sosa Pagán J, Del Cid W, Han J, Philpot B. Allelic specificity of Ube3a expression in the mouse brain during postnatal development. J Comp Neurol. 2014;522:1874-96 pubmed publisher