This is a Validated Antibody Database (VAD) review about human Tyk2, based on 6 published articles (read how Labome selects the articles), using Tyk2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tyk2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tyk2 synonym: IMD35; JTK1; non-receptor tyrosine-protein kinase TYK2

Invitrogen
rabbit polyclonal
  • western blot; mouse; fig 4
In order to study the effects of HDAC6 modulation using antigen presenting cells, Invitrogen Tyk2 antibody (Thermo Scientific, PA5-34497) was used in western blot on mouse samples (fig 4). J Immunol (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to study the effect of bluetongue virus on type I interferon response, Invitrogen Tyk2 antibody (Pierce Biotechnology, PA5-17898) was used in western blot on human samples . J Virol (2014) ncbi
Abcam
rabbit polyclonal
  • western blot; human; loading ...; fig 7b
Abcam Tyk2 antibody (Abcam, ab138394) was used in western blot on human samples (fig 7b). Cell Physiol Biochem (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 7b
Abcam Tyk2 antibody (Abcam, ab223733) was used in western blot on human samples (fig 7b). Cell Physiol Biochem (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-8)
  • western blot; human
Santa Cruz Biotechnology Tyk2 antibody (Santa Cruz Biotechnology, sc-5271) was used in western blot on human samples . Viral Immunol (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology Tyk2 antibody (Cell Signaling, 9321) was used in western blot on human samples at 1:1000 (fig 6a). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to investigate the effect of a microtubule inhibitor, MPT0B098, on STAT3 signaling in oral squamous cell carcinoma, Cell Signaling Technology Tyk2 antibody (Cell Signaling, 9312) was used in western blot on human samples (fig 3). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to investigate the effect of a microtubule inhibitor, MPT0B098, on STAT3 signaling in oral squamous cell carcinoma, Cell Signaling Technology Tyk2 antibody (Cell Signaling, 9321) was used in western blot on human samples (fig 3). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
In order to study the effects of HDAC6 modulation using antigen presenting cells, Cell Signaling Technology Tyk2 antibody (Cell signaling, 9321) was used in western blot on mouse samples (fig 4). J Immunol (2014) ncbi
Articles Reviewed
  1. Yin D, Li Y, Fu C, Feng Y. Pro-Angiogenic Role of LncRNA HULC in Microvascular Endothelial Cells via Sequestrating miR-124. Cell Physiol Biochem. 2018;50:2188-2202 pubmed publisher
  2. Eletto D, Burns S, Angulo I, Plagnol V, Gilmour K, Henriquez F, et al. Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection. Nat Commun. 2016;7:13992 pubmed publisher
  3. Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed publisher
  4. Cheng F, Lienlaf M, Wang H, Perez Villarroel P, Lee C, Woan K, et al. A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. J Immunol. 2014;193:2850-62 pubmed publisher
  5. Doceul V, Chauveau E, Lara E, Breard E, Sailleau C, Zientara S, et al. Dual modulation of type I interferon response by bluetongue virus. J Virol. 2014;88:10792-802 pubmed publisher
  6. Liu Y, Zhang Z, Zhao X, Yu R, Zhang X, Wu S, et al. Enterovirus 71 inhibits cellular type I interferon signaling by downregulating JAK1 protein expression. Viral Immunol. 2014;27:267-76 pubmed publisher