This is a Validated Antibody Database (VAD) review about human Tiam1, based on 4 published articles (read how Labome selects the articles), using Tiam1 antibody in all methods. It is aimed to help Labome visitors find the most suited Tiam1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tiam1 synonym: TIAM-1; T-lymphoma invasion and metastasis-inducing protein 1; human T-lymphoma invasion and metastasis inducing TIAM1 protein

Santa Cruz Biotechnology
mouse monoclonal (E-7)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1aa
  • western blot; human; 1:300; loading ...; fig 1e
Santa Cruz Biotechnology Tiam1 antibody (Santa Cruz, sc-393315) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1aa) and in western blot on human samples at 1:300 (fig 1e). Exp Cell Res (2018) ncbi
R&D Systems
sheep polyclonal
  • immunocytochemistry; human; 1:200; fig 2
R&D Systems Tiam1 antibody (R&D Systems, AF5038) was used in immunocytochemistry on human samples at 1:200 (fig 2). Nat Commun (2015) ncbi
sheep polyclonal
  • western blot; mouse; 1:200
R&D Systems Tiam1 antibody (R&D Systems, AF5038) was used in western blot on mouse samples at 1:200. Genes Dev (2013) ncbi
EMD Millipore
rabbit polyclonal
  • immunocytochemistry; human; fig 5k
EMD Millipore Tiam1 antibody (EMD Millipore, ST1070) was used in immunocytochemistry on human samples (fig 5k). J Cell Biol (2015) ncbi
Articles Reviewed
  1. Liu L, Wu B, Cai H, Li D, Ma Y, Zhu X, et al. Tiam1 promotes thyroid carcinoma metastasis by modulating EMT via Wnt/?-catenin signaling. Exp Cell Res. 2018;362:532-540 pubmed publisher
  2. Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed publisher
  3. Artym V, Swatkoski S, Matsumoto K, Campbell C, Petrie R, Dimitriadis E, et al. Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. J Cell Biol. 2015;208:331-50 pubmed publisher
  4. Nakayama A, Nakayama M, Turner C, Höing S, Lepore J, Adams R. Ephrin-B2 controls PDGFR? internalization and signaling. Genes Dev. 2013;27:2576-89 pubmed publisher