This is a Validated Antibody Database (VAD) review about human TXNRD1, based on 10 published articles (read how Labome selects the articles), using TXNRD1 antibody in all methods. It is aimed to help Labome visitors find the most suited TXNRD1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TXNRD1 synonym: GRIM-12; TR1; TRXR1; TXNR; thioredoxin reductase 1, cytoplasmic; KM-102-derived reductase-like factor; gene associated with retinoic and IFN-induced mortality 12 protein; gene associated with retinoic and interferon-induced mortality 12 protein; oxidoreductase; testis tissue sperm-binding protein Li 46a; thioredoxin reductase GRIM-12; thioredoxin reductase TR1

Abcam
rabbit monoclonal (EPNCIR129)
  • western blot; human; 1:2000; loading ...; fig s1c
Abcam TXNRD1 antibody (Abcam, ab124954) was used in western blot on human samples at 1:2000 (fig s1c). Atherosclerosis (2019) ncbi
rabbit polyclonal
  • western blot; human; fig 2a
Abcam TXNRD1 antibody (Abcam, ab16840) was used in western blot on human samples (fig 2a). Placenta (2017) ncbi
rabbit monoclonal (EPNCIR129)
  • immunohistochemistry - paraffin section; human; 1:800; fig 1
  • immunocytochemistry; human; 1:10,000; fig 2
  • western blot; human; fig 2
Abcam TXNRD1 antibody (Abcam, ab124954) was used in immunohistochemistry - paraffin section on human samples at 1:800 (fig 1), in immunocytochemistry on human samples at 1:10,000 (fig 2) and in western blot on human samples (fig 2). Lab Invest (2016) ncbi
rabbit monoclonal (EPNCIR129)
  • western blot; rat; 1:2000
  • western blot; mouse; 1:2000
In order to investigate the mechanism for the neuroprotective effect of Klotho, Abcam TXNRD1 antibody (Abcam, ab124954) was used in western blot on rat samples at 1:2000 and in western blot on mouse samples at 1:2000. J Biol Chem (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-2)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Santa Cruz Biotechnology TXNRD1 antibody (Santa Cruz, sc-28321) was used in immunohistochemistry - paraffin section on human samples (fig 1a). J Biol Chem (2017) ncbi
mouse monoclonal (19A1)
  • western blot; human; fig 5a
Santa Cruz Biotechnology TXNRD1 antibody (santa cruz, sc-58444) was used in western blot on human samples (fig 5a). Sci Adv (2016) ncbi
mouse monoclonal (A-9)
  • western blot; human; fig 7
Santa Cruz Biotechnology TXNRD1 antibody (Santa Cruz, sc-365658) was used in western blot on human samples (fig 7). Autophagy (2015) ncbi
mouse monoclonal (19A1)
  • western blot; human; 1:2000; fig 2
Santa Cruz Biotechnology TXNRD1 antibody (SantaCruz Biotechnology, 19A1) was used in western blot on human samples at 1:2000 (fig 2). Cell Death Dis (2015) ncbi
mouse monoclonal (B-2)
  • western blot; human; 1:1000
Santa Cruz Biotechnology TXNRD1 antibody (Santa Cruz Biotechnology, SC-28321) was used in western blot on human samples at 1:1000. Asian J Androl (2013) ncbi
Invitrogen
mouse monoclonal (19A1)
  • western blot; human
In order to study the effect of oxidative stress on human selenoproteins, Invitrogen TXNRD1 antibody (Euromedex, LF-MA0015) was used in western blot on human samples . J Biol Chem (2014) ncbi
Articles Reviewed
  1. Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  2. Li M, Cheng W, Luo J, Hu X, Nie T, Lai H, et al. Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway. Placenta. 2017;55:81-89 pubmed publisher
  3. Lou M, Liu Q, Ren G, Zeng J, Xiang X, Ding Y, et al. Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy. J Biol Chem. 2017;292:9136-9149 pubmed publisher
  4. Dóka Ã, Pader I, Bíró A, Johansson K, Cheng Q, Ballagó K, et al. A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems. Sci Adv. 2016;2:e1500968 pubmed publisher
  5. Ahrens T, Timme S, Ostendorp J, Bogatyreva L, Hoeppner J, Hopt U, et al. Response of esophageal cancer cells to epigenetic inhibitors is mediated via altered thioredoxin activity. Lab Invest. 2016;96:307-16 pubmed publisher
  6. Artero Castro A, Perez Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed publisher
  7. Xu J, Eriksson S, Cebula M, Sandalova T, Hedström E, Pader I, et al. The conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell death. Cell Death Dis. 2015;6:e1616 pubmed publisher
  8. Zeldich E, Chen C, Colvin T, Bove Fenderson E, Liang J, Tucker Zhou T, et al. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. J Biol Chem. 2014;289:24700-15 pubmed publisher
  9. Touat Hamici Z, Legrain Y, Bulteau A, Chavatte L. Selective up-regulation of human selenoproteins in response to oxidative stress. J Biol Chem. 2014;289:14750-61 pubmed publisher
  10. Ozdemirler Erata G, Kucukgergin C, Aktan G, Kadioglu A, Uysal M, Kocak Toker N. Is thioredoxin reductase involved in the defense against DNA fragmentation in varicocele?. Asian J Androl. 2013;15:518-22 pubmed publisher