This is a Validated Antibody Database (VAD) review about human TUBB4A, based on 25 published articles (read how Labome selects the articles), using TUBB4A antibody in all methods. It is aimed to help Labome visitors find the most suited TUBB4A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TUBB4A synonym: DYT4; TUBB4; beta-5; tubulin beta-4A chain; dystonia 4, torsion (autosomal dominant); tubulin beta-4 chain; tubulin, beta 4; tubulin, beta, 5

Abcam
mouse monoclonal (ONS.1A6)
  • immunocytochemistry; human; fig 4a
In order to investigate T2R14 activation by flavones in sinonasal cilia during upper respiratory infections, Abcam TUBB4A antibody (Abcam, ab11315) was used in immunocytochemistry on human samples (fig 4a). J Biol Chem (2017) ncbi
mouse monoclonal (ONS.1A6)
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 3
Abcam TUBB4A antibody (Abcam, ab11315) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (ONS.1A6)
  • immunocytochemistry; human; fig 1
In order to evaluate the differential responses to H3N2 influenza virus infection in vitro in human nasal epithelial cells derived from multiple subjects, Abcam TUBB4A antibody (Abcam, ab11315) was used in immunocytochemistry on human samples (fig 1). J Allergy Clin Immunol (2016) ncbi
mouse monoclonal (ONS.1A6)
  • immunohistochemistry - paraffin section; human; fig 3
In order to characterize Chinese nasal polyp, Abcam TUBB4A antibody (Abcam, ONS.1A6) was used in immunohistochemistry - paraffin section on human samples (fig 3). Int Forum Allergy Rhinol (2016) ncbi
Sigma-Aldrich
mouse monoclonal (SAP.4G5)
  • immunocytochemistry; dog; 1:500; loading ...; fig 8d
In order to investigate that role of zonula occludens-2 in Rho protein activation and epithelial development, Sigma-Aldrich TUBB4A antibody (Sigma-Aldrich, T7816) was used in immunocytochemistry on dog samples at 1:500 (fig 8d). Biochim Biophys Acta Mol Cell Res (2017) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; mouse; 1:2000; fig s1
  • western blot; human; 1:2000; fig 1
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on mouse samples at 1:2000 (fig s1) and in western blot on human samples at 1:2000 (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (SAP.4G5)
  • immunocytochemistry; human; 1:500; loading ...; fig 2a
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in immunocytochemistry on human samples at 1:500 (fig 2a). FEBS Lett (2016) ncbi
mouse monoclonal (SAP.4G5)
  • immunohistochemistry; cow; loading ...
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in immunohistochemistry on cow samples . J Biol Chem (2016) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; chicken; 1:10,000; fig 2
In order to compare manganese detoxification/efflux proteins and molecular characterization of ZnT10 as a manganese transporter, Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on chicken samples at 1:10,000 (fig 2). J Biol Chem (2016) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human; 1:2000; fig 2
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on human samples at 1:2000 (fig 2). EMBO Mol Med (2016) ncbi
mouse monoclonal (ONS.1A6)
  • immunohistochemistry - frozen section; mouse; tbl 1
Sigma-Aldrich TUBB4A antibody (Sigma, T7941) was used in immunohistochemistry - frozen section on mouse samples (tbl 1). PLoS ONE (2016) ncbi
mouse monoclonal (ONS.1A6)
  • western blot; mouse; 1:5000; fig 1
Sigma-Aldrich TUBB4A antibody (Sigma, 1A6) was used in western blot on mouse samples at 1:5000 (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (ONS.1A6)
  • immunocytochemistry; mouse; fig 5a
In order to characterize airway epithelial cells derived from induced pluripotent stem cells, Sigma-Aldrich TUBB4A antibody (Sigma, T7941) was used in immunocytochemistry on mouse samples (fig 5a). Cell Tissue Res (2016) ncbi
mouse monoclonal (ONS.1A6)
  • western blot; human; fig 4
Sigma-Aldrich TUBB4A antibody (Sigma, T7941) was used in western blot on human samples (fig 4). Oncotarget (2015) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human; fig 4
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on human samples (fig 4). Oncotarget (2015) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human; fig s7
Sigma-Aldrich TUBB4A antibody (santa Cruz, T7816) was used in western blot on human samples (fig s7). PLoS Pathog (2015) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human; 1:20,000; fig 5
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on human samples at 1:20,000 (fig 5). Oncotarget (2015) ncbi
mouse monoclonal (ONS.1A6)
  • immunohistochemistry; human; 1:100
In order to characterize human tracheal basal cells, Sigma-Aldrich TUBB4A antibody (Sigma, T7941) was used in immunohistochemistry on human samples at 1:100. Respir Res (2014) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human; 1:50000
Sigma-Aldrich TUBB4A antibody (Sigma Aldrich, T7816) was used in western blot on human samples at 1:50000. Biochim Biophys Acta (2015) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human; 1:500; fig 3
In order to investigate the regulation of d-serine synthesis, Sigma-Aldrich TUBB4A antibody (Sigma-Aldrich, T7816) was used in western blot on human samples at 1:500 (fig 3). J Biol Chem (2014) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; mouse; 1:20000
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on mouse samples at 1:20000. PLoS ONE (2014) ncbi
mouse monoclonal (ONS.1A6)
  • immunocytochemistry; human
Sigma-Aldrich TUBB4A antibody (Sigma-Aldrich, ONS.1A6) was used in immunocytochemistry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human
In order to assess the therapeutic potential of ganitumab for the treatment of ovarian cancer, Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on human samples . Clin Cancer Res (2014) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human
In order to show that FRS2alpha is a component of the VEGF receptors, Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on human samples . Proc Natl Acad Sci U S A (2014) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; human
In order to study mechanisms of microtubule hyperacetylation, Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (SAP.4G5)
  • western blot; green monkey; 1:20000
Sigma-Aldrich TUBB4A antibody (Sigma, T7816) was used in western blot on green monkey samples at 1:20000. J Virol (2014) ncbi
Articles Reviewed
  1. Raya Sandino A, Castillo Kauil A, Domínguez Calderón A, Alarcón L, Flores Benitez D, Cuellar Perez F, et al. Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. Biochim Biophys Acta Mol Cell Res. 2017;1864:1714-1733 pubmed publisher
  2. Hariri B, McMahon D, Chen B, Freund J, Mansfield C, Doghramji L, et al. Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor. J Biol Chem. 2017;292:8484-8497 pubmed publisher
  3. Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed publisher
  4. Tambe M, Narvi E, Kallio M. Reduced levels of Dusp3/Vhr phosphatase impair normal spindle bipolarity in an Erk1/2 activity-dependent manner. FEBS Lett. 2016;590:2757-67 pubmed publisher
  5. Chen G, Mickolajczyk K, Hancock W. The Kinesin-5 Chemomechanical Cycle Is Dominated by a Two-heads-bound State. J Biol Chem. 2016;291:20283-20294 pubmed publisher
  6. Nishito Y, Tsuji N, Fujishiro H, Takeda T, Yamazaki T, Teranishi F, et al. Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter. J Biol Chem. 2016;291:14773-87 pubmed publisher
  7. Chen P, Qin L, Li G, Tellides G, Simons M. Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression. EMBO Mol Med. 2016;8:712-28 pubmed publisher
  8. PACKARD A, Lin B, Schwob J. Sox2 and Pax6 Play Counteracting Roles in Regulating Neurogenesis within the Murine Olfactory Epithelium. PLoS ONE. 2016;11:e0155167 pubmed publisher
  9. Antony N, McDougall A, Mantamadiotis T, Cole T, Bird A. Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms. Sci Rep. 2016;6:25569 pubmed publisher
  10. Kato Y, Katsuki T, Kokubo H, Masuda A, Saga Y. Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells. Nat Commun. 2016;7:11272 pubmed publisher
  11. Yan Y, Tan K, Li C, Tran T, Chao S, Sugrue R, et al. Human nasal epithelial cells derived from multiple subjects exhibit differential responses to H3N2 influenza virus infection in vitro. J Allergy Clin Immunol. 2016;138:276-281.e15 pubmed publisher
  12. Yoshie S, Imaizumi M, Nakamura R, Otsuki K, Ikeda M, Nomoto Y, et al. Generation of airway epithelial cells with native characteristics from mouse induced pluripotent stem cells. Cell Tissue Res. 2016;364:319-30 pubmed publisher
  13. Wu S, Guo Z, Hopkins C, Wei N, Chu E, Wipf P, et al. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells. Oncotarget. 2015;6:40866-79 pubmed publisher
  14. Gao T, Ng C, Li C, Li Y, Duan C, Shen L, et al. Smoking is an independent association of squamous metaplasia in Chinese nasal polyps. Int Forum Allergy Rhinol. 2016;6:66-74 pubmed publisher
  15. Pentecost M, Vashisht A, Lester T, Voros T, Beaty S, Park A, et al. Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. PLoS Pathog. 2015;11:e1004739 pubmed publisher
  16. Annala M, Kivinummi K, Tuominen J, Karakurt S, Granberg K, Latonen L, et al. Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer. Oncotarget. 2015;6:6235-50 pubmed
  17. Van de Laar E, Clifford M, Hasenoeder S, Kim B, Wang D, Lee S, et al. Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas. Respir Res. 2014;15:160 pubmed publisher
  18. Poschmann G, Grzendowski M, Stefanski A, Bruns E, Meyer H, Stühler K. Redox proteomics reveal stress responsive proteins linking peroxiredoxin-1 status in glioma to chemosensitivity and oxidative stress. Biochim Biophys Acta. 2015;1854:624-31 pubmed publisher
  19. Dikopoltsev E, Foltyn V, Zehl M, Jensen O, Mori H, Radzishevsky I, et al. FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. J Biol Chem. 2014;289:33904-15 pubmed publisher
  20. Jamin A, Thunuguntla P, Wicklund A, Jones C, Wiebe M. Barrier to auto integration factor becomes dephosphorylated during HSV-1 Infection and Can Act as a host defense by impairing viral DNA replication and gene expression. PLoS ONE. 2014;9:e100511 pubmed publisher
  21. de Borja Callejas F, Martinez Anton A, Alobid I, Fuentes M, Cortijo J, Picado C, et al. Reconstituted human upper airway epithelium as 3-d in vitro model for nasal polyposis. PLoS ONE. 2014;9:e100537 pubmed publisher
  22. Beltran P, Calzone F, Mitchell P, Chung Y, Cajulis E, Moody G, et al. Ganitumab (AMG 479) inhibits IGF-II-dependent ovarian cancer growth and potentiates platinum-based chemotherapy. Clin Cancer Res. 2014;20:2947-58 pubmed publisher
  23. Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, et al. The docking protein FRS2? is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014;111:5514-9 pubmed publisher
  24. Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
  25. Jamin A, Wicklund A, Wiebe M. Cell- and virus-mediated regulation of the barrier-to-autointegration factor's phosphorylation state controls its DNA binding, dimerization, subcellular localization, and antipoxviral activity. J Virol. 2014;88:5342-55 pubmed publisher