This is a Validated Antibody Database (VAD) review about human TSPO, based on 16 published articles (read how Labome selects the articles), using TSPO antibody in all methods. It is aimed to help Labome visitors find the most suited TSPO antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TSPO synonym: BPBS; BZRP; DBI; IBP; MBR; PBR; PBS; PKBS; PTBR; mDRC; pk18

Knockout validation
Abcam
domestic rabbit monoclonal (EPR5384)
  • western blot knockout validation; mouse; fig 1
Abcam TSPO antibody (Abcam, ab109497) was used in western blot knockout validation on mouse samples (fig 1). Endocrinology (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR5384)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3d
Abcam TSPO antibody (Abcam, ab109497) was used in immunohistochemistry - frozen section on mouse samples (fig 3d). J Endocr Soc (2020) ncbi
domestic rabbit monoclonal (EPR5384)
  • immunohistochemistry; mouse; loading ...; fig 1a
Abcam TSPO antibody (abcam, ab109497) was used in immunohistochemistry on mouse samples (fig 1a). Int J Mol Sci (2018) ncbi
domestic rabbit monoclonal (EPR5384)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig s2
Abcam TSPO antibody (Abcam, ab109497) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s2). Epilepsia (2018) ncbi
domestic rabbit monoclonal (EPR5384)
  • western blot; mouse; loading ...; fig 6g
Abcam TSPO antibody (Abcam, ab109497) was used in western blot on mouse samples (fig 6g). Cell Death Dis (2017) ncbi
domestic rabbit monoclonal (EPR5384)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 3a,3b,3c
Abcam TSPO antibody (Abcam, 109497) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 3a,3b,3c). J Neuroinflammation (2017) ncbi
domestic rabbit monoclonal (EPR5384)
  • western blot knockout validation; mouse; fig 1
Abcam TSPO antibody (Abcam, ab109497) was used in western blot knockout validation on mouse samples (fig 1). Endocrinology (2016) ncbi
domestic rabbit monoclonal (EPR5384)
  • immunohistochemistry; mouse; 1:200; fig ev1
In order to study the role of microglial phagocytosis of living photoreceptors in retinal degeneration, Abcam TSPO antibody (abcam, ab109497) was used in immunohistochemistry on mouse samples at 1:200 (fig ev1). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (EPR5384)
  • western blot; mouse; 1:10000
Abcam TSPO antibody (Abcam, ab109497) was used in western blot on mouse samples at 1:10000. Cell Death Differ (2013) ncbi
Enzo Life Sciences
mouse monoclonal (MBr1)
  • flow cytometry; human; loading ...; fig 1a
Enzo Life Sciences TSPO antibody (Enzo, Mbr1) was used in flow cytometry on human samples (fig 1a). Oncotarget (2016) ncbi
mouse monoclonal (MBr1)
Enzo Life Sciences TSPO antibody (Enzo Life Sciences, MBr1) was used . J Biol Chem (2015) ncbi
mouse monoclonal (MBr1)
  • ELISA; human; loading ...; fig 2a
Enzo Life Sciences TSPO antibody (Enzo Life Sciences, MBr1) was used in ELISA on human samples (fig 2a). J Virol (2015) ncbi
mouse monoclonal (MBr1)
  • blocking or activating experiments; Trachemys dorbigni
Enzo Life Sciences TSPO antibody (Enzo Life Sciences, MBr1) was used in blocking or activating experiments on Trachemys dorbigni samples . J Biol Chem (2012) ncbi
mouse monoclonal (MBr1)
  • flow cytometry; human
Enzo Life Sciences TSPO antibody (Alexis Biochemicals / Enzo Life Sciences, MBr1) was used in flow cytometry on human samples . J Mol Cell Biol (2011) ncbi
LifeSpan Biosciences
domestic rabbit polyclonal
  • western blot; rat; 1:500; loading ...; fig 9f
LifeSpan Biosciences TSPO antibody (LS Bio, LS-B14234) was used in western blot on rat samples at 1:500 (fig 9f). J Neuroinflammation (2020) ncbi
Invitrogen
domestic goat polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 4a
In order to use quantitative proteomics to find biomarkers for human hepatocellular carcinoma, Invitrogen TSPO antibody (ThermoFisher Scientific, PA5-18565) was used in immunohistochemistry - paraffin section on human samples (fig 4a). Biomarkers (2017) ncbi
MilliporeSigma
mouse monoclonal
  • flow cytometry; human; 1:1000
MilliporeSigma TSPO antibody (Sigma-Aldrich, SAB1405525) was used in flow cytometry on human samples at 1:1000. Oncol Lett (2015) ncbi
Articles Reviewed
  1. Fan J, Campioli E, Sottas C, Zirkin B, Papadopoulos V. Amhr2-Cre-Mediated Global Tspo Knockout. J Endocr Soc. 2020;4:bvaa001 pubmed publisher
  2. Giridharan V, Collodel A, Generoso J, Scaini G, Wassather R, Selvaraj S, et al. Neuroinflammation trajectories precede cognitive impairment after experimental meningitis-evidence from an in vivo PET study. J Neuroinflammation. 2020;17:5 pubmed publisher
  3. Betlazar C, Harrison Brown M, Middleton R, Banati R, Liu G. Cellular Sources and Regional Variations in the Expression of the Neuroinflammatory Marker Translocator Protein (TSPO) in the Normal Brain. Int J Mol Sci. 2018;19: pubmed publisher
  4. Weidner L, Kannan P, Mitsios N, Kang S, Hall M, Theodore W, et al. The expression of inflammatory markers and their potential influence on efflux transporters in drug-resistant mesial temporal lobe epilepsy tissue. Epilepsia. 2018;59:1507-1517 pubmed publisher
  5. Gatliff J, East D, Singh A, Alvarez M, Frison M, Matic I, et al. A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling. Cell Death Dis. 2017;8:e2896 pubmed publisher
  6. Zhao L, Li J, Fu Y, Zhang M, Wang B, Ouellette J, et al. Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration. J Neuroinflammation. 2017;14:14 pubmed publisher
  7. Megger D, Rosowski K, Ahrens M, Bracht T, Eisenacher M, Schlaak J, et al. Tissue-based quantitative proteome analysis of human hepatocellular carcinoma using tandem mass tags. Biomarkers. 2017;22:113-122 pubmed publisher
  8. Breiman A, López Robles M, de Carné Trécesson S, Echasserieau K, Bernardeau K, Drickamer K, et al. Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin). Oncotarget. 2016;7:14064-82 pubmed publisher
  9. Tu L, Zhao A, Hussein M, Stocco D, Selvaraj V. Translocator Protein (TSPO) Affects Mitochondrial Fatty Acid Oxidation in Steroidogenic Cells. Endocrinology. 2016;157:1110-21 pubmed publisher
  10. Zhao L, Zabel M, Wang X, Ma W, Shah P, Fariss R, et al. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med. 2015;7:1179-97 pubmed publisher
  11. Matsumoto S, Nakao H, Kawabe K, Nonaka M, Toyoda H, Takishima Y, et al. A Cytotoxic Antibody Recognizing Lacto-N-fucopentaose I (LNFP I) on Human Induced Pluripotent Stem (hiPS) Cells. J Biol Chem. 2015;290:20071-85 pubmed publisher
  12. DE Rosa A, Zappavigna S, Villa M, Improta S, Cesario E, Mastrullo L, et al. Prognostic role of translocator protein and oxidative stress markers in chronic lymphocytic leukemia patients treated with bendamustine plus rituximab. Oncol Lett. 2015;9:1327-1332 pubmed
  13. Zhang D, Huang P, Zou L, Lowary T, Tan M, Jiang X. Tulane virus recognizes the A type 3 and B histo-blood group antigens. J Virol. 2015;89:1419-27 pubmed publisher
  14. Faccenda D, Tan C, Seraphim A, Duchen M, Campanella M. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013;20:686-97 pubmed publisher
  15. Benktander J, Angstrom J, Breimer M, Teneberg S. Redefinition of the carbohydrate binding specificity of Helicobacter pylori BabA adhesin. J Biol Chem. 2012;287:31712-24 pubmed publisher
  16. Suila H, Pitkänen V, Hirvonen T, Heiskanen A, Anderson H, Laitinen A, et al. Are globoseries glycosphingolipids SSEA-3 and -4 markers for stem cells derived from human umbilical cord blood?. J Mol Cell Biol. 2011;3:99-107 pubmed publisher