This is a Validated Antibody Database (VAD) review about human TRPM8, based on 5 published articles (read how Labome selects the articles), using TRPM8 antibody in all methods. It is aimed to help Labome visitors find the most suited TRPM8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TRPM8 synonym: LTRPC6; LTrpC-6; TRPP8; trp-p8; transient receptor potential cation channel subfamily M member 8; TRPM8 cationic channel; transient receptor potential p8; transient receptor potential subfamily M member 8

Abcam
rabbit monoclonal (EPR4196(2))
  • western blot; mouse; 1:1000; fig 1
Abcam TRPM8 antibody (abcam, ab109308) was used in western blot on mouse samples at 1:1000 (fig 1). FASEB J (2016) ncbi
rabbit monoclonal (EPR4196(2))
  • immunocytochemistry; human; loading ...; fig 5a
  • western blot; human; loading ...; fig s1b
Abcam TRPM8 antibody (Abcam, Ab109308) was used in immunocytochemistry on human samples (fig 5a) and in western blot on human samples (fig s1b). Oncotarget (2016) ncbi
Alomone Labs
rabbit polyclonal
  • western blot; human; fig 1
Alomone Labs TRPM8 antibody (Alomone, ACC-049) was used in western blot on human samples (fig 1). Proc Natl Acad Sci U S A (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; fig 3
Alomone Labs TRPM8 antibody (Alomone Labs, ACC-049) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3). Mucosal Immunol (2015) ncbi
rabbit polyclonal
  • neutralization; human
In order to study the use of antibodies recognizing transient receptor potential melastatin channel 8 (TRPM8) as antagonists, Alomone Labs TRPM8 antibody (Alomone labs, ACC-049) was used in neutralization on human samples . PLoS ONE (2014) ncbi
Invitrogen
rabbit polyclonal
  • blocking or activating experiments; human
In order to study the use of antibodies recognizing transient receptor potential melastatin channel 8 (TRPM8) as antagonists, Invitrogen TRPM8 antibody (Thermo Scientific, OST00133W) was used in blocking or activating experiments on human samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Borowiec A, Sion B, Chalmel F, D Rolland A, Lemonnier L, De Clerck T, et al. Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation. FASEB J. 2016;30:3155-70 pubmed publisher
  2. Bidaux G, Borowiec A, Dubois C, Delcourt P, Schulz C, Vanden Abeele F, et al. Targeting of short TRPM8 isoforms induces 4TM-TRPM8-dependent apoptosis in prostate cancer cells. Oncotarget. 2016;7:29063-80 pubmed publisher
  3. Bidaux G, Borowiec A, Gordienko D, Beck B, Shapovalov G, Lemonnier L, et al. Epidermal TRPM8 channel isoform controls the balance between keratinocyte proliferation and differentiation in a cold-dependent manner. Proc Natl Acad Sci U S A. 2015;112:E3345-54 pubmed publisher
  4. de Jong P, Takahashi N, Peiris M, Bertin S, Lee J, Gareau M, et al. TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP. Mucosal Immunol. 2015;8:491-504 pubmed publisher
  5. Miller S, Rao S, Wang W, Liu H, Wang J, Gavva N. Antibodies to the extracellular pore loop of TRPM8 act as antagonists of channel activation. PLoS ONE. 2014;9:e107151 pubmed publisher