This is a Validated Antibody Database (VAD) review about human TRPM2, based on 7 published articles (read how Labome selects the articles), using TRPM2 antibody in all methods. It is aimed to help Labome visitors find the most suited TRPM2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TRPM2 synonym: EREG1; KNP3; LTRPC2; LTrpC-2; NUDT9H; NUDT9L1; TRPC7; transient receptor potential cation channel subfamily M member 2; estrogen-responsive element-associated gene 1 protein; long transient receptor potential channel 2; transient receptor potential channel 7; transient receptor potential melastatin 2

Bethyl
rabbit polyclonal
  • western blot; human; 1:300; fig 2
Bethyl TRPM2 antibody (Bethyl Laboratories, A300-414A-2) was used in western blot on human samples at 1:300 (fig 2). Oxid Med Cell Longev (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2.a,b,c
Bethyl TRPM2 antibody (Bethyl Laboratories, A300-414A) was used in western blot on human samples at 1:1000 (fig 2.a,b,c). Oncol Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Bethyl TRPM2 antibody (Bethyl Laboratories, A300-414A) was used in western blot on human samples at 1:1000. Int J Oncol (2015) ncbi
LifeSpan Biosciences
goat polyclonal
  • immunocytochemistry; human; fig 5
  • western blot; human; 1:1000; fig 5
In order to study the contribution of TRPM2 in hyperglycemia-induced oxidative stress, LifeSpan Biosciences TRPM2 antibody (LifeSpan BioSciences, LS-B4122) was used in immunocytochemistry on human samples (fig 5) and in western blot on human samples at 1:1000 (fig 5). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; fig 7
LifeSpan Biosciences TRPM2 antibody (LifeSpan BioScience, LS-C141843) was used in immunohistochemistry on mouse samples (fig 7). Front Neurosci (2016) ncbi
Novus Biologicals
rabbit polyclonal
  • western blot; mouse; fig 3
Novus Biologicals TRPM2 antibody (Novus Biologicals, NB110-81601) was used in western blot on mouse samples (fig 3). Cardiovasc Res (2014) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; loading ...; fig 2f
In order to report the effects of long-term lipopolysaccharide exposure on monocytes, Invitrogen TRPM2 antibody (Thermo Fischer Scientific, PA5-22218) was used in western blot on human samples (fig 2f). Toxicol In Vitro (2017) ncbi
Articles Reviewed
  1. Mytych J, Romerowicz Misielak M, Koziorowski M. Long-term culture with lipopolysaccharide induces dose-dependent cytostatic and cytotoxic effects in THP-1 monocytes. Toxicol In Vitro. 2017;42:1-9 pubmed publisher
  2. Tseng H, Vong C, Kwan Y, Lee S, Hoi M. TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells. Sci Rep. 2016;6:35016 pubmed publisher
  3. Zhong J, Amina S, Liang M, Akther S, Yuhi T, Nishimura T, et al. Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice. Front Neurosci. 2016;10:304 pubmed publisher
  4. Klumpp D, Misovic M, Szteyn K, Shumilina E, Rudner J, Huber S. Targeting TRPM2 Channels Impairs Radiation-Induced Cell Cycle Arrest and Fosters Cell Death of T Cell Leukemia Cells in a Bcl-2-Dependent Manner. Oxid Med Cell Longev. 2016;2016:8026702 pubmed publisher
  5. Koh D, Powell D, Blake S, Hoffman J, Hopkins M, Feng X. Enhanced cytotoxicity in triple-negative and estrogen receptor‑positive breast adenocarcinoma cells due to inhibition of the transient receptor potential melastatin-2 channel. Oncol Rep. 2015;34:1589-98 pubmed publisher
  6. Hopkins M, Feng X, Liu M, Parker L, Koh D. Inhibition of the transient receptor potential melastatin-2 channel causes increased DNA damage and decreased proliferation in breast adenocarcinoma cells. Int J Oncol. 2015;46:2267-76 pubmed publisher
  7. Roberge S, Roussel J, Andersson D, Meli A, Vidal B, Blandel F, et al. TNF-?-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes. Cardiovasc Res. 2014;103:90-9 pubmed publisher