This is a Validated Antibody Database (VAD) review about human TRIM63, based on 107 published articles (read how Labome selects the articles), using TRIM63 antibody in all methods. It is aimed to help Labome visitors find the most suited TRIM63 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TRIM63 synonym: IRF; MURF1; MURF2; RNF28; SMRZ

Santa Cruz Biotechnology
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1j
  • western blot; mouse; 1:1000; loading ...; fig 1h
Santa Cruz Biotechnology TRIM63 antibody (Santa Cruz, sc-398608) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1j) and in western blot on mouse samples at 1:1000 (fig 1h). Antioxidants (Basel) (2021) ncbi
mouse monoclonal
  • western blot; rat; loading ...; fig 6b
Santa Cruz Biotechnology TRIM63 antibody (Santa Cruz, sc-398608) was used in western blot on rat samples (fig 6b). Oncotarget (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR6431(2))
  • western blot; mouse; 1:1000; fig 2g
In order to study the function of OPA1 in FGF21 secretion from muscle, Abcam TRIM63 antibody (Abcam, Ab172479) was used in western blot on mouse samples at 1:1000 (fig 2g). EMBO J (2017) ncbi
domestic rabbit monoclonal (EPR6431(2))
  • western blot; rat; 1:1000; loading ...; fig 2d
In order to assess the possible mechanism underlying the protective effect of tetramethylpyrazine against disuse-induced muscle atrophy, Abcam TRIM63 antibody (Abcam, ab172479) was used in western blot on rat samples at 1:1000 (fig 2d). Appl Physiol Nutr Metab (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947S) was used in western blot on mouse samples (fig 3b). J Immunother Cancer (2022) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 5e
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples (fig 5e). iScience (2022) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 2k
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2k). iScience (2022) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:200; loading ...; fig 4i
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:200 (fig 4i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; pigs ; loading ...; fig 1i
Cell Signaling Technology TRIM63 antibody (CST, 4947) was used in western blot on pigs samples (fig 1i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:500; loading ...; fig 1i
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947S) was used in western blot on human samples at 1:500 (fig 1i). Cell Rep (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 2g
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947S) was used in western blot on mouse samples (fig 2g). Cell Rep (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 5h
Cell Signaling Technology TRIM63 antibody (CST, 4947) was used in western blot on mouse samples (fig 5h). J Nutr Biochem (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:2000
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:2000. Cell Syst (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:1000. Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 3f
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 3f). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (4D4G)
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technologies, 4947) was used . Cell Death Discov (2021) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947S) was used in western blot on mouse samples at 1:1000 (fig 4a). elife (2020) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; loading ...; fig 8b
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples at 1:1000 (fig 8b). Nat Commun (2020) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:2000; loading ...; fig 3f
  • western blot; human; 1:2000; loading ...; fig 1i, 2c
Cell Signaling Technology TRIM63 antibody (CST, 4947) was used in western blot on mouse samples at 1:2000 (fig 3f) and in western blot on human samples at 1:2000 (fig 1i, 2c). Nat Commun (2020) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; loading ...; fig 2h
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig 2h). elife (2020) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology TRIM63 antibody (CST, 4947) was used in western blot on human samples (fig 4a). Biomed Pharmacother (2020) ncbi
domestic rabbit monoclonal (4D4G)
  • proximity ligation assay; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4D4G) was used in proximity ligation assay on human samples at 1:1000 (fig 3a). Nature (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig s4f
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947S) was used in western blot on mouse samples (fig s4f). Science (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples . PLoS Pathog (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 2c). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 2f
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2f). J Immunol (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2c). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 5f
Cell Signaling Technology TRIM63 antibody (CST, 4947) was used in western blot on human samples (fig 5f). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4D4G) was used in western blot on human samples (fig 7a). PLoS Pathog (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947S) was used in western blot on human samples (fig 5b). Front Immunol (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947s) was used in western blot on mouse samples (fig 3d). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; loading ...; fig 3a, 3c, s3d
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig 3a, 3c, s3d). Sci Adv (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology TRIM63 antibody (CST, 4947) was used in western blot on human samples (fig 3e). Cell Death Dis (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 6c
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples (fig 6c). Immunity (2019) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology TRIM63 antibody (Biosciences, 4947) was used in western blot on mouse samples (fig 1a). Cell Death Differ (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:500; loading ...; fig 2d, 2l
  • western blot; mouse; 1:500; loading ...; fig 1p, 5g, 6f
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4D4G) was used in western blot on human samples at 1:500 (fig 2d, 2l) and in western blot on mouse samples at 1:500 (fig 1p, 5g, 6f). Nat Commun (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4b). J Virol (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; loading ...; fig s4a
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig s4a). Nat Commun (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 4d
Cell Signaling Technology TRIM63 antibody ((Cell Signaling Technology, 4947) was used in western blot on mouse samples (fig 4d). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:500; loading ...; fig 4b
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:500 (fig 4b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 5f
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 5f). J Immunol (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 9d
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 9d). J Cell Biol (2018) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 5b). Cell (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 6d
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 6d). Immunity (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig s17c
In order to study the effects of interleukin-10 on macrophages and inflammation, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig s17c). Science (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:5000; loading ...; fig 3a
In order to describe the mechanism by which FBXW7 stabilizes RigI, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:5000 (fig 3a). Nat Commun (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; loading ...; fig 3a
In order to analyze the effects of dopamine related metabolite concentrations in M1 and M2 microglia phenotypes, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4,947) was used in western blot on mouse samples at 1:1000 (fig 3a). Front Cell Neurosci (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:1000; loading ...; fig 7b
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4D4G) was used in western blot on human samples at 1:1000 (fig 7b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 2a, 3a
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 2a, 3a) and in western blot on human samples (fig 2b). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 2d
In order to find interferon-gamma inducible factor 16 functions in the cyclic GMP-AMP synthase-stimulator of interferon genes pathway, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947s) was used in western blot on human samples (fig 2d). Nat Commun (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 2A
  • western blot; human; loading ...; fig 5A
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 2A) and in western blot on human samples (fig 5A). Biochem J (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 5a
In order to describe factors regulating RIG-I/IRF3 signaling activity, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 5a). Mol Cell (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4a). Nucleic Acids Res (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4a). MBio (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 6
  • western blot; human; fig 6
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 6) and in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples (fig 4a). Immunology (2017) ncbi
domestic rabbit monoclonal (4D4G)
  • immunocytochemistry; human; 1:50; loading ...; fig 4f
In order to research the effect of intracellular STING inactivation on the drug sensitivity of breast cancer cells, Cell Signaling Technology TRIM63 antibody (Cell signaling, 4947) was used in immunocytochemistry on human samples at 1:50 (fig 4f). Oncotarget (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; fig 4
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:200; loading ...; fig 3f
In order to develop and characterize a murine model of hepatitis A virus, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:200 (fig 3f). Science (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; Chinese tree shrew; fig 5d
In order to investigate the evolution of RIG-I-like receptors, Cell Signaling Technology TRIM63 antibody (Cell signaling, 4947) was used in western blot on Chinese tree shrew samples (fig 5d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 7c
Cell Signaling Technology TRIM63 antibody (Cell signaling, 4947) was used in western blot on human samples (fig 7c). J Neuroinflammation (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:2000; fig 5
  • western blot; mouse; 1:2000; fig 5
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947S) was used in western blot on human samples at 1:2000 (fig 5) and in western blot on mouse samples at 1:2000 (fig 5). BMC Biol (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 6
In order to demonstrate that OTULIN is essential for preventing TNF-associated systemic inflammation in humans and mice, Cell Signaling Technology TRIM63 antibody (Cell Signaling Tech, 4947) was used in western blot on mouse samples (fig 6). Cell (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 8
Cell Signaling Technology TRIM63 antibody (Cell signaling, 4947S) was used in western blot on mouse samples (fig 8). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 4c
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 4c). BMC Complement Altern Med (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; loading ...; fig 2e
  • western blot; human; 1:1000; loading ...; fig 1g
In order to explore the anti-viral effects of iRhom2, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples at 1:1000 (fig 2e) and in western blot on human samples at 1:1000 (fig 1g). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig s9
In order to study the impact of p21 signaling on monocyte reprogramming, Cell Signaling Technology TRIM63 antibody (cell signalling, 4947) was used in western blot on mouse samples (fig s9). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 6c
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples (fig 6c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; fig 6
In order to utilize CRISPR/Cas9 knock-out cell lines and vaccinia virus mutants to elucidate opposing roles of double-stranded RNA effector pathways and viral defense proteins, Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 6). J Virol (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; fig 3
  • western blot; African green monkey; 1:1000; fig 1
In order to learn the requirement of palmitoylation at the Golgi by activation of STING, Cell Signaling Technology TRIM63 antibody (Cell Signalling, 4D4G) was used in western blot on mouse samples at 1:1000 (fig 3) and in western blot on African green monkey samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:1000; fig s13
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947S) was used in western blot on human samples at 1:1000 (fig s13). Nat Commun (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 1a
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 1a). J Virol (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology TRIM63 antibody (Cell signaling, 4947) was used in western blot on mouse samples (fig 4a). elife (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 3
  • western blot; human; fig 3
Cell Signaling Technology TRIM63 antibody (Cell Signaling Tech, 4947) was used in western blot on mouse samples (fig 3) and in western blot on human samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; fig 4
Cell Signaling Technology TRIM63 antibody (Cell signaling, 4947S) was used in western blot on human samples (fig 4). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947S) was used in western blot on human samples (fig 2b). Cell Res (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; fig s2
Cell Signaling Technology TRIM63 antibody (Cell Signaling Tech, 4947S) was used in western blot on human samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
In order to determine a therapeutic strategy to target the IRF4 network in multiple myeloma by using the bromodomain inhibition of the transcriptional coactivators CBP/EP300, Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4948) was used in western blot on human samples (fig 5). elife (2016) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 11
In order to identify small molecules that activate the type I interferon response via IFN regulatory factor 3, Cell Signaling Technology TRIM63 antibody (cell Signaling, 4947) was used in western blot on mouse samples (fig 11). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 1
Cell Signaling Technology TRIM63 antibody (CST, 4947S) was used in western blot on mouse samples (fig 1). Proc Natl Acad Sci U S A (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 1
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947s) was used in western blot on mouse samples (fig 1). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 4
  • western blot; human; fig 4
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 4) and in western blot on human samples (fig 4). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig S9
In order to generate mathematical models of the host inflammatory response induced by virulent influenza strains, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig S9). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples . J Virol (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 1
In order to study inhibitors of bromodomain and extra-terminal (BET) family members by suppression of interferon beta gene transcription, Cell Signaling Technology TRIM63 antibody (Cell Signaling Technologies, 4947) was used in western blot on mouse samples (fig 1). Biochem J (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000; fig s2
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig s2). Nat Commun (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; fig 4
  • western blot; human; fig 4
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 4) and in western blot on human samples (fig 4). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:1000; fig 3c
In order to identify gene variants that contribute to amyotrophic lateral sclerosis, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples at 1:1000 (fig 3c). Nat Neurosci (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; fig 1
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4D4G) was used in western blot on mouse samples (fig 4a). J Immunol (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:500; loading ...; fig 4
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:500 (fig 4). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4D4G) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
domestic rabbit monoclonal (4D4G)
  • chromatin immunoprecipitation; human; fig 4
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in chromatin immunoprecipitation on human samples (fig 4). Nucleic Acids Res (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; fig 2
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2). Basic Res Cardiol (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse
In order to study the relationship between adenosine deaminase acting on RNA 1 (ADAR1) and type I IFNs, Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples . J Immunol (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples . J Virol (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • immunohistochemistry - frozen section; mouse; 1:500
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Neurosci Res (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; fig 4f
In order to elucidate type I interferon-independent viral immune responses, Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4f). Nat Immunol (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse
Cell Signaling Technology TRIM63 antibody (Cell Signaling, 4947) was used in western blot on mouse samples . PLoS Pathog (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:1000
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:1000. PLoS ONE (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:1,000
In order to study the mechanism for the oncolytic measles virus replication, Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947S) was used in western blot on human samples at 1:1,000. J Virol (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; human; 1:1000
Cell Signaling Technology TRIM63 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:1000. J Virol (2014) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse; 1:1000
Cell Signaling Technology TRIM63 antibody (cst, 4947) was used in western blot on mouse samples at 1:1000. Mol Cell Endocrinol (2013) ncbi
domestic rabbit monoclonal (4D4G)
  • western blot; mouse
Cell Signaling Technology TRIM63 antibody (CST, 4947) was used in western blot on mouse samples . Immunity (2012) ncbi
Articles Reviewed
  1. Ni H, Zhang H, Li L, Huang H, Guo H, Zhang L, et al. T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer. J Immunother Cancer. 2022;10: pubmed publisher
  2. Zhao X, Hu S, Zeng L, Liu X, Song Y, Zhang Y, et al. Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING-mediated T cell activation. iScience. 2022;25:104690 pubmed publisher
  3. Tan H, Yong Y, Xue Y, Liu H, Furihata T, Shankar E, et al. cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model. iScience. 2022;25:104404 pubmed publisher
  4. Sun L, Li Y, Misumi I, Gonzalez Lopez O, Hensley L, Cullen J, et al. IRF3-mediated pathogenicity in a murine model of human hepatitis A. PLoS Pathog. 2021;17:e1009960 pubmed publisher
  5. Wang Z, Chen J, Wu X, Ma D, Zhang X, Li R, et al. PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection. PLoS Pathog. 2021;17:e1009940 pubmed publisher
  6. Bruand M, Barras D, Mina M, Ghisoni E, Morotti M, Lanitis E, et al. Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING. Cell Rep. 2021;36:109412 pubmed publisher
  7. Shen Y, Tang K, Chen D, Hong M, Sun F, Wang S, et al. Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation. Cell Rep. 2021;35:109272 pubmed publisher
  8. Choi E, Jeong J, Jang H, Ahn Y, Kim K, An H, et al. Skeletal Lipocalin-2 Is Associated with Iron-Related Oxidative Stress in ob/ob Mice with Sarcopenia. Antioxidants (Basel). 2021;10: pubmed publisher
  9. Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed publisher
  10. Lopacinski A, Sweatt A, Smolko C, Gray Gaillard E, Borgman C, Shah M, et al. Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. Cell Syst. 2021;12:304-323.e13 pubmed publisher
  11. Guo G, Gao M, Gao X, Zhu B, Huang J, Luo K, et al. SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response. Signal Transduct Target Ther. 2021;6:119 pubmed publisher
  12. Yu Z, Li X, Yang M, Huang J, Fang Q, Jia J, et al. TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO. Signal Transduct Target Ther. 2021;6:90 pubmed publisher
  13. Lee J, Park I, Kwak M, Rhee W, Kim S, Shin J. HMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells. Cell Death Discov. 2021;7:28 pubmed publisher
  14. Tao L, Lemoff A, Wang G, Zarek C, Lowe A, Yan N, et al. Reactive oxygen species oxidize STING and suppress interferon production. elife. 2020;9: pubmed publisher
  15. Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, et al. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke. Nat Commun. 2020;11:2488 pubmed publisher
  16. Deng M, Tam J, Wang L, Liang K, Li S, Zhang L, et al. TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination. Nat Commun. 2020;11:2193 pubmed publisher
  17. Weindel C, Bell S, Vail K, West K, Patrick K, Watson R. LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis. elife. 2020;9: pubmed publisher
  18. Cai H, Yan L, Liu N, Xu M, Cai H. IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway. Biomed Pharmacother. 2020;123:109790 pubmed publisher
  19. Luteijn R, Zaver S, Gowen B, Wyman S, Garelis N, Onia L, et al. SLC19A1 transports immunoreactive cyclic dinucleotides. Nature. 2019;573:434-438 pubmed publisher
  20. Liu Y, You Y, Lu Z, Yang J, Li P, Liu L, et al. N6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019;365:1171-1176 pubmed publisher
  21. Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed publisher
  22. Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed publisher
  23. Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed publisher
  24. Zhang W, Wang G, Xu Z, Tu H, Hu F, Dai J, et al. Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019;: pubmed publisher
  25. Liu C, Li X, Nan F, Jiang S, Gao X, Guo S, et al. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. Cell. 2019;177:865-880.e21 pubmed publisher
  26. Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen K, Grøvdal L, et al. The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathog. 2019;15:e1007684 pubmed publisher
  27. Guan X, Zhang M, Fu M, Luo S, Hu Q. Herpes Simplex Virus Type 2 Immediate Early Protein ICP27 Inhibits IFN-β Production in Mucosal Epithelial Cells by Antagonizing IRF3 Activation. Front Immunol. 2019;10:290 pubmed publisher
  28. Tan Y, Kagan J. Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019;: pubmed publisher
  29. Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed publisher
  30. Majumdar T, Sharma S, Kumar M, Hussain M, Chauhan N, Kalia I, et al. Tryptophan-kynurenine pathway attenuates β-catenin-dependent pro-parasitic role of STING-TICAM2-IRF3-IDO1 signalosome in Toxoplasma gondii infection. Cell Death Dis. 2019;10:161 pubmed publisher
  31. Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed publisher
  32. Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, et al. STING directly activates autophagy to tune the innate immune response. Cell Death Differ. 2018;: pubmed publisher
  33. Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed publisher
  34. Qi D, Hu L, Jiao T, Zhang T, Tong X, Ye X. Phosphatase Cdc25A Negatively Regulates the Antiviral Immune Response by Inhibiting TBK1 Activity. J Virol. 2018;92: pubmed publisher
  35. Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher
  36. Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed publisher
  37. Yang L, Wang L, Ketkar H, Ma J, Yang G, Cui S, et al. UBXN3B positively regulates STING-mediated antiviral immune responses. Nat Commun. 2018;9:2329 pubmed publisher
  38. Ahmad R, Al Roub A, Kochumon S, Akther N, Thomas R, Kumari M, et al. The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. J Immunol. 2018;200:3599-3611 pubmed publisher
  39. Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed publisher
  40. Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed publisher
  41. Nguyen T, Smith B, Tate M, Belz G, Barrios M, Elgass K, et al. SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition. Immunity. 2017;47:498-509.e6 pubmed publisher
  42. Pereira R, Tadinada S, Zasadny F, Oliveira K, Pires K, Olvera A, et al. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017;36:2126-2145 pubmed publisher
  43. Ip W, Hoshi N, Shouval D, Snapper S, Medzhitov R. Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages. Science. 2017;356:513-519 pubmed publisher
  44. Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, et al. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017;8:14654 pubmed publisher
  45. Shan M, Lin S, Li S, Du Y, Zhao H, Hong H, et al. TIR-Domain-Containing Adapter-Inducing Interferon-? (TRIF) Is Essential for MPTP-Induced Dopaminergic Neuroprotection via Microglial Cell M1/M2 Modulation. Front Cell Neurosci. 2017;11:35 pubmed publisher
  46. Almine J, O Hare C, Dunphy G, Haga I, Naik R, Atrih A, et al. IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes. Nat Commun. 2017;8:14392 pubmed publisher
  47. Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed publisher
  48. Jønsson K, Laustsen A, Krapp C, Skipper K, Thavachelvam K, Hotter D, et al. IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP. Nat Commun. 2017;8:14391 pubmed publisher
  49. Bakshi S, Taylor J, Strickson S, McCartney T, Cohen P. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon ?. Biochem J. 2017;474:1163-1174 pubmed publisher
  50. Willemsen J, Wicht O, Wolanski J, Baur N, Bastian S, Haas D, et al. Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening. Mol Cell. 2017;65:403-415.e8 pubmed publisher
  51. Suspène R, Mussil B, Laude H, Caval V, Berry N, Bouzidi M, et al. Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage. Nucleic Acids Res. 2017;45:3231-3241 pubmed publisher
  52. Hu N, Chang H, Du B, Zhang Q, Arfat Y, Dang K, et al. Tetramethylpyrazine ameliorated disuse-induced gastrocnemius muscle atrophy in hindlimb unloading rats through suppression of Ca2+/ROS-mediated apoptosis. Appl Physiol Nutr Metab. 2017;42:117-127 pubmed publisher
  53. Cai B, Wu J, Yu X, Su X, Wang R. FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions. MBio. 2017;8: pubmed publisher
  54. Boro M, Singh V, Balaji K. Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses. Sci Rep. 2016;6:37695 pubmed publisher
  55. Li J, Chen T, Xiao M, Li N, Wang S, Su H, et al. Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1. Oncotarget. 2016;7:86648-86659 pubmed publisher
  56. Klaska I, Muckersie E, Martin Granados C, Christofi M, Forrester J. Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms. Immunology. 2017;150:364-377 pubmed publisher
  57. Gaston J, Cheradame L, Yvonnet V, Déas O, Poupon M, Judde J, et al. Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents. Oncotarget. 2016;7:77205-77224 pubmed publisher
  58. Omura H, Oikawa D, Nakane T, Kato M, Ishii R, Ishitani R, et al. Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. Sci Rep. 2016;6:34756 pubmed publisher
  59. Huai W, Song H, Yu Z, Wang W, Han L, Sakamoto T, et al. Mint3 potentiates TLR3/4- and RIG-I-induced IFN-? expression and antiviral immune responses. Proc Natl Acad Sci U S A. 2016;113:11925-11930 pubmed
  60. Hirai Yuki A, Hensley L, McGivern D, Gonzalez Lopez O, Das A, Feng H, et al. MAVS-dependent host species range and pathogenicity of human hepatitis A virus. Science. 2016;353:1541-1545 pubmed
  61. Xu L, Yu D, Fan Y, Peng L, Wu Y, Yao Y. Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew. Proc Natl Acad Sci U S A. 2016;113:10950-5 pubmed publisher
  62. Zhang X, Zheng Z, Liu X, Shu B, Mao P, Bai B, et al. Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. J Neuroinflammation. 2016;13:209 pubmed publisher
  63. Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed publisher
  64. Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher
  65. Wang W, Jiang M, Liu S, Zhang S, Liu W, Ma Y, et al. RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation. Proc Natl Acad Sci U S A. 2016;113:9581-6 pubmed publisher
  66. Meliopoulos V, Van De Velde L, Van De Velde N, Karlsson E, Neale G, Vogel P, et al. An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. PLoS Pathog. 2016;12:e1005804 pubmed publisher
  67. Kim J, Weeratunga P, Kim M, Nikapitiya C, Lee B, Uddin M, et al. Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo. BMC Complement Altern Med. 2016;16:265 pubmed publisher
  68. Luo W, Li S, Li C, Lian H, Yang Q, Zhong B, et al. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING. Nat Immunol. 2016;17:1057-66 pubmed publisher
  69. Rackov G, Hernandez Jimenez E, Shokri R, Carmona Rodríguez L, Manes S, Alvarez Mon M, et al. p21 mediates macrophage reprogramming through regulation of p50-p50 NF-?B and IFN-?. J Clin Invest. 2016;126:3089-103 pubmed publisher
  70. Liu C, Yue R, Yang Y, Cui Y, Yang L, Zhao D, et al. AIM2 inhibits autophagy and IFN-? production during M. bovis infection. Oncotarget. 2016;7:46972-46987 pubmed publisher
  71. Liu R, Moss B. Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants. J Virol. 2016;90:7864-79 pubmed publisher
  72. Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
  73. Lin W, Zhang J, Lin H, Li Z, Sun X, Xin D, et al. Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD. Nat Commun. 2016;7:11848 pubmed publisher
  74. Anghelina D, Lam E, Falck Pedersen E. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016;90:5915-27 pubmed publisher
  75. Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher
  76. Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed publisher
  77. Zhao K, Zhang M, Zhang L, Wang P, Song G, Liu B, et al. Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response. Sci Rep. 2016;6:23771 pubmed publisher
  78. Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher
  79. Qin Y, Liu Q, Tian S, Xie W, Cui J, Wang R. TRIM9 short isoform preferentially promotes DNA and RNA virus-induced production of type I interferon by recruiting GSK3? to TBK1. Cell Res. 2016;26:613-28 pubmed publisher
  80. Zhang G, Chan B, Samarina N, Abere B, Weidner Glunde M, Buch A, et al. Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proc Natl Acad Sci U S A. 2016;113:E1034-43 pubmed publisher
  81. Conery A, Centore R, Neiss A, Keller P, Joshi S, Spillane K, et al. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. elife. 2016;5: pubmed publisher
  82. Sali T, Pryke K, Abraham J, Liu A, Archer I, Broeckel R, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015;11:e1005324 pubmed publisher
  83. Lin D, Zhang M, Zhang M, Ren Y, Jin J, Zhao Q, et al. Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6. Proc Natl Acad Sci U S A. 2015;112:11324-9 pubmed publisher
  84. Wang Y, Lian Q, Yang B, Yan S, Zhou H, He L, et al. TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING. PLoS Pathog. 2015;11:e1005012 pubmed publisher
  85. Khan K, Dô F, Marineau A, Doyon P, Clément J, Woodgett J, et al. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Mol Cell Biol. 2015;35:3029-43 pubmed publisher
  86. Shoemaker J, Fukuyama S, Eisfeld A, Zhao D, Kawakami E, Sakabe S, et al. An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation. PLoS Pathog. 2015;11:e1004856 pubmed publisher
  87. Guo X, Liu T, Shi H, Wang J, Ji P, Wang H, et al. Respiratory Syncytial Virus Infection Upregulates NLRC5 and Major Histocompatibility Complex Class I Expression through RIG-I Induction in Airway Epithelial Cells. J Virol. 2015;89:7636-45 pubmed publisher
  88. Malik N, Vollmer S, Nanda S, López Pelaéz M, Prescott A, Gray N, et al. Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members. Biochem J. 2015;468:363-72 pubmed publisher
  89. Dong T, Li C, Wang X, Dian L, Zhang X, Li L, et al. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nat Commun. 2015;6:6522 pubmed publisher
  90. Majumdar T, Chattopadhyay S, Ozhegov E, Dhar J, Goswami R, Sen G, et al. Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii. PLoS Pathog. 2015;11:e1004779 pubmed publisher
  91. Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci. 2015;18:631-6 pubmed publisher
  92. Kemp M, Lindsey Boltz L, Sancar A. UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1). J Biol Chem. 2015;290:12184-94 pubmed publisher
  93. Liu Y, Zhang Q, Ding Y, Li X, Zhao D, Zhao K, et al. Histone lysine methyltransferase Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing Tollip. J Immunol. 2015;194:2838-46 pubmed publisher
  94. Kodigepalli K, Nanjundan M. Induction of PLSCR1 in a STING/IRF3-dependent manner upon vector transfection in ovarian epithelial cells. PLoS ONE. 2015;10:e0117464 pubmed publisher
  95. Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, et al. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015;290:1269-80 pubmed publisher
  96. Banerjee A, Kim Y, Kim T. A novel virus-inducible enhancer of the interferon-β gene with tightly linked promoter and enhancer activities. Nucleic Acids Res. 2014;42:12537-54 pubmed publisher
  97. Fork C, Hitzel J, Nichols B, Tikkanen R, Brandes R. Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells. Basic Res Cardiol. 2014;109:439 pubmed publisher
  98. Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, et al. Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. J Immunol. 2014;193:3436-45 pubmed publisher
  99. Yen B, Mulder L, Martinez O, Basler C. Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation. J Virol. 2014;88:12500-10 pubmed publisher
  100. Hayakawa K, Okazaki R, Morioka K, Nakamura K, Tanaka S, Ogata T. Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury. J Neurosci Res. 2014;92:1647-58 pubmed publisher
  101. Odendall C, Dixit E, Stavru F, Bierne H, Franz K, Durbin A, et al. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014;15:717-26 pubmed publisher
  102. Huang Y, Liu H, Li S, Tang Y, Wei B, Yu H, et al. MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection. PLoS Pathog. 2014;10:e1004020 pubmed publisher
  103. Nandi S, Chanda S, Bagchi P, Nayak M, Bhowmick R, Chawla Sarkar M. MAVS protein is attenuated by rotavirus nonstructural protein 1. PLoS ONE. 2014;9:e92126 pubmed publisher
  104. Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, et al. Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. J Virol. 2014;88:5152-64 pubmed publisher
  105. Das A, Dinh P, Panda D, Pattnaik A. Interferon-inducible protein IFI35 negatively regulates RIG-I antiviral signaling and supports vesicular stomatitis virus replication. J Virol. 2014;88:3103-13 pubmed publisher
  106. Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, et al. Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells. Mol Cell Endocrinol. 2013;372:73-85 pubmed publisher
  107. Austenaa L, Barozzi I, Chronowska A, Termanini A, Ostuni R, Prosperini E, et al. The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis. Immunity. 2012;36:572-85 pubmed publisher