This is a Validated Antibody Database (VAD) review about human TRIM59, based on 3 published articles (read how Labome selects the articles), using TRIM59 antibody in all methods. It is aimed to help Labome visitors find the most suited TRIM59 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TRIM59 synonym: IFT80L; MRF1; RNF104; TRIM57; TSBF1

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 2b
Abcam TRIM59 antibody (Abcam, ab69639) was used in western blot knockout validation on human samples (fig 2b). PLoS Biol (2018) ncbi
Abcam
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:50; loading ...; fig 1a
  • western blot; human; 1:500; loading ...; fig 6a, 8d
Abcam TRIM59 antibody (Abcam, ab69639) was used in immunocytochemistry on human samples at 1:50 (fig 1a) and in western blot on human samples at 1:500 (fig 6a, 8d). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 2b
Abcam TRIM59 antibody (Abcam, ab69639) was used in western blot knockout validation on human samples (fig 2b). PLoS Biol (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 7f
Abcam TRIM59 antibody (Abcam, ab69639) was used in western blot on mouse samples (fig 7f). Cell Death Dis (2018) ncbi
Articles Reviewed
  1. Sang Y, Li Y, Zhang Y, Alvarez A, Yu B, Zhang W, et al. CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity. Nat Commun. 2019;10:4013 pubmed publisher
  2. Tan P, Ye Y, He L, Xie J, Jing J, Ma G, et al. TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10. PLoS Biol. 2018;16:e3000051 pubmed publisher
  3. Su X, Wu C, Ye X, Zeng M, Zhang Z, Che Y, et al. Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development. Cell Death Dis. 2018;9:302 pubmed publisher