This is a Validated Antibody Database (VAD) review about human TRG, based on 33 published articles (read how Labome selects the articles), using TRG antibody in all methods. It is aimed to help Labome visitors find the most suited TRG antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TRG synonym: TCRG; TRG@; T-cell antigen receptor, gamma polypeptide; T-cell rearranging gene, gamma; T-cell receptor, gamma cluster; TCRG, TRG@

Invitrogen
mouse monoclonal (5A6.E9)
  • blocking or activating experiments; human; fig 2a
In order to identify a role for CK2 in healthy human thymocytes in the selection of the gamma delta T-cell lineage, Invitrogen TRG antibody (ThermoFisher, 5A6.E9) was used in blocking or activating experiments on human samples (fig 2a). Leukemia (2017) ncbi
mouse monoclonal (5A6.E9)
  • flow cytometry; human; loading ...; tbl 1
In order to demonstrate that freezing already-stained samples suspended in 10% DMSO in FBS is practical and efficient way to preserve already-stained samples for mass cytometry assessment, Invitrogen TRG antibody (Invitrogen, 5A6.E9) was used in flow cytometry on human samples (tbl 1). Cytometry A (2017) ncbi
mouse monoclonal (5A6.E9)
  • immunohistochemistry - paraffin section; human
In order to study the clinicopathologic spectrum of gastrointestinal T-cell lymphoma based on immunophenotypes, Invitrogen TRG antibody (Thermo Scientific, 5A6.E9) was used in immunohistochemistry - paraffin section on human samples . Am J Surg Pathol (2016) ncbi
mouse monoclonal (5A6.E9)
  • immunohistochemistry - paraffin section; mouse; fig 4
In order to evaluate alleviation from psoriatic inflammation by programmed cell death ligand 1 and suppression of IL-17A production from programmed cell death 1-high T cells, Invitrogen TRG antibody (Thermo Fisher, 5A6.E91) was used in immunohistochemistry - paraffin section on mouse samples (fig 4). J Allergy Clin Immunol (2016) ncbi
mouse monoclonal (5A6.E9)
  • flow cytometry; human; 2:25; fig 1
In order to utilize mass cytometry for multiplexed peptide-MHC tetramer staining, Invitrogen TRG antibody (Invitrogen, 5A6.E9) was used in flow cytometry on human samples at 2:25 (fig 1). Methods Mol Biol (2015) ncbi
mouse monoclonal (5A6.E9)
  • immunohistochemistry; human; tbl 2
In order to characterize Forkhead box protein 3-positive T cell lymphoma, in the absence of human T cell lymphotrophic virus type 1 infection, Invitrogen TRG antibody (Thermo Fisher Scientific, 5A6.E9) was used in immunohistochemistry on human samples (tbl 2). Histopathology (2016) ncbi
mouse monoclonal (5A6.E9)
  • immunohistochemistry; human; tbl 2
In order to clarify the histological and genomic profiles of Japanese cases of enteropathy-associated T-cell lymphoma, Invitrogen TRG antibody (Thermo Scientific, 5A6. E9) was used in immunohistochemistry on human samples (tbl 2). Mod Pathol (2015) ncbi
mouse monoclonal (5A6.E9)
  • immunohistochemistry - frozen section; human; 1:100; fig 2
In order to discuss the role of T cells in Rasmussen encephalitis, Invitrogen TRG antibody (Thermo Scientific, 5A6.E9) was used in immunohistochemistry - frozen section on human samples at 1:100 (fig 2). J Neuroinflammation (2015) ncbi
mouse monoclonal (5A6.E9)
  • immunohistochemistry; human; tbl 4
In order to compare the clinicopathologic profiles of patients with nodal Epstein-Barr virus cytotoxic T-cell lymphoma with those with extranasal NK/T-cell lymphoma, Invitrogen TRG antibody (Thermo Fisher Scientific, 5A6.E9) was used in immunohistochemistry on human samples (tbl 4). Am J Surg Pathol (2015) ncbi
mouse monoclonal (7A5)
  • flow cytometry; human
In order to examine the effect of HMBPP-deficient Listeria mutant immunization, Invitrogen TRG antibody (Thermo Scientific, 7A5) was used in flow cytometry on human samples . J Leukoc Biol (2014) ncbi
mouse monoclonal (5A6.E9)
  • flow cytometry; human
In order to investigate the antiviral activity of gammadelta T cells against influenza viruses, Invitrogen TRG antibody (Invitrogen, 5A6.E9) was used in flow cytometry on human samples . J Infect Dis (2009) ncbi
mouse monoclonal (5A6.E9)
  • flow cytometry; sheep
  • flow cytometry; goat
In order to describe new reagents to study T cell populations in different animal species and analyze antibodies useful for studying gamma-delta T cell populations in primates, Invitrogen TRG antibody (Caltag, 5A6.E9) was used in flow cytometry on sheep samples and in flow cytometry on goat samples . Cytometry A (2007) ncbi
mouse monoclonal (5A6.E9)
  • flow cytometry; human
In order to investigate the role of leukocyte immunoglobulin-like receptor (CD85j) during infection with malaria, Invitrogen TRG antibody (Caltag, 5A6.E9) was used in flow cytometry on human samples . Eur Cytokine Netw (2006) ncbi
mouse monoclonal (5A6.E9)
  • flow cytometry; African green monkey
In order to use cynomolgus macaques as a model to study Vgamma2/Vdelta2 T-cell responses to non-peptidic antigens, Invitrogen TRG antibody (Caltag, 5A6.E9) was used in flow cytometry on African green monkey samples . Immunology (2005) ncbi
mouse monoclonal (7A5)
  • flow cytometry; human
In order to study gamma delta T cell activation, Invitrogen TRG antibody (Endogen, 7A5) was used in flow cytometry on human samples . Clin Exp Immunol (2004) ncbi
mouse monoclonal (5A6.E9)
  • flow cytometry; human
In order to study gamma delta T cell activation, Invitrogen TRG antibody (Endogen, 5A6.E9) was used in flow cytometry on human samples . Clin Exp Immunol (2004) ncbi
BioLegend
mouse monoclonal (B3)
  • flow cytometry; human; loading ...; tbl s9
In order to optimize and assess potential malaria vaccine regimens, BioLegend TRG antibody (BioLegend, 331310) was used in flow cytometry on human samples (tbl s9). Nature (2017) ncbi
mouse monoclonal (B1)
  • flow cytometry; human; 1:10; loading ...; fig 4a
In order to measure CD11d expression on lymphocyte subsets using flow cytometry, BioLegend TRG antibody (BioLegend, B1) was used in flow cytometry on human samples at 1:10 (fig 4a). J Leukoc Biol (2017) ncbi
mouse monoclonal (B1)
  • flow cytometry; human; loading ...; fig s1c
In order to demonstrate that neonatal CD8 positive T cells have a specific genetic program biased toward the innate immune response, BioLegend TRG antibody (BioLegend, B1) was used in flow cytometry on human samples (fig s1c). Cell Rep (2016) ncbi
mouse monoclonal (B1)
  • flow cytometry; human; loading ...; fig 1a
In order to characterize CD8 positive alpha beta gamma delta T cells, BioLegend TRG antibody (BioLegend, B1) was used in flow cytometry on human samples (fig 1a). J Immunol (2016) ncbi
mouse monoclonal (B3)
  • flow cytometry; human; fig 7
In order to investigate how organ-specific Btnl genes shape local T cell compartments, BioLegend TRG antibody (Biolegend, 331308) was used in flow cytometry on human samples (fig 7). Cell (2016) ncbi
mouse monoclonal (B1)
  • flow cytometry; human; loading ...; fig 1c
BioLegend TRG antibody (BioLegend, B1) was used in flow cytometry on human samples (fig 1c). J Immunol (2016) ncbi
mouse monoclonal (B1)
  • flow cytometry; human; 1:50; fig s3
BioLegend TRG antibody (Biolegend, 331218) was used in flow cytometry on human samples at 1:50 (fig s3). Nat Commun (2015) ncbi
mouse monoclonal (B1)
  • flow cytometry; human; tbl 1
BioLegend TRG antibody (BioLegend, B1) was used in flow cytometry on human samples (tbl 1). J Immunol (2015) ncbi
mouse monoclonal (B1)
  • flow cytometry; human; fig 4
BioLegend TRG antibody (Biolegend, B1) was used in flow cytometry on human samples (fig 4). Cytokine (2015) ncbi
mouse monoclonal (B1)
  • flow cytometry; chimpanzee
In order to study the in vitro response of gammadelta T-cell subsets from HIV1-infected and control chimpanzees to T-cell activators, BioLegend TRG antibody (BioLegend, B1) was used in flow cytometry on chimpanzee samples . J Med Primatol (2014) ncbi
Beckman Coulter
mouse monoclonal (IMMU510)
  • flow cytometry; human; loading ...; fig s1a
In order to use CD49a expression to define subsets of tissue-resident memory T cells in the skin, Beckman Coulter TRG antibody (Beckman Coulter, IMMU510) was used in flow cytometry on human samples (fig s1a). Immunity (2017) ncbi
mouse monoclonal (IMMU510)
  • flow cytometry; human; loading ...; tbl 1
In order to report the function of CD70-CD27 signaling in patients infected with Epstein-Barr virus, Beckman Coulter TRG antibody (Beckman Coulter, IMMU510) was used in flow cytometry on human samples (tbl 1). J Exp Med (2017) ncbi
mouse monoclonal (IMMU510)
  • flow cytometry; human; loading ...; fig 2
In order to develop a functional assay to assess the risk of developing acute graft-versus-host disease, Beckman Coulter TRG antibody (Beckman Coulter, IMMU510) was used in flow cytometry on human samples (fig 2). J Immunol Res (2016) ncbi
mouse monoclonal (IMMU510)
  • flow cytometry; human; fig 4
Beckman Coulter TRG antibody (Beckman Coulter, IMMU510) was used in flow cytometry on human samples (fig 4). Infect Immun (2015) ncbi
mouse monoclonal (IMMU 360)
  • flow cytometry; human; fig 3
In order to investigate when Vgamma9Vdelta2 T cells develop, Beckman Coulter TRG antibody (Beckman Coulter, IMMU360) was used in flow cytometry on human samples (fig 3). Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (IMMU510)
  • flow cytometry; human
In order to identify the role of GammaDelta T cells in acute HIV infection, Beckman Coulter TRG antibody (Immunotech, IMMU510) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (IMMU 360)
  • blocking or activating experiments; human; 1-20 ug/ml
  • flow cytometry; human
Beckman Coulter TRG antibody (Beckman Coulter, Immu360) was used in blocking or activating experiments on human samples at 1-20 ug/ml and in flow cytometry on human samples . J Immunol (2014) ncbi
mouse monoclonal (IMMU 360)
  • flow cytometry; common squirrel monkey
In order to discuss available reagents for studying the neotropical primate squirrel monkey, Beckman Coulter TRG antibody (Beckman, IMMU 360) was used in flow cytometry on common squirrel monkey samples . J Immunol Methods (2005) ncbi
Articles Reviewed
  1. Cheuk S, Schlums H, Gallais Sérézal I, Martini E, Chiang S, Marquardt N, et al. CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin. Immunity. 2017;46:287-300 pubmed publisher
  2. Mordmuller B, Surat G, Lagler H, Chakravarty S, Ishizuka A, Lalremruata A, et al. Sterile protection against human malaria by chemoattenuated PfSPZ vaccine. Nature. 2017;542:445-449 pubmed publisher
  3. Izawa K, Martin E, Soudais C, Bruneau J, Boutboul D, Rodriguez R, et al. Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection. J Exp Med. 2017;214:73-89 pubmed publisher
  4. Sairafi D, Stikvoort A, Gertow J, Mattsson J, Uhlin M. Donor Cell Composition and Reactivity Predict Risk of Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation. J Immunol Res. 2016;2016:5601204 pubmed
  5. Ribeiro S, Tesio M, Ribot J, Macintyre E, Barata J, Silva Santos B. Casein kinase 2 controls the survival of normal thymic and leukemic ?? T cells via promotion of AKT signaling. Leukemia. 2017;31:1603-1610 pubmed publisher
  6. Siegers G, Barreira C, Postovit L, Dekaban G. CD11d ?2 integrin expression on human NK, B, and ?? T cells. J Leukoc Biol. 2017;101:1029-1035 pubmed publisher
  7. Galindo Albarrán A, López Portales O, Gutiérrez Reyna D, Rodríguez Jorge O, Sánchez Villanueva J, Ramirez Pliego O, et al. CD8+ T Cells from Human Neonates Are Biased toward an Innate Immune Response. Cell Rep. 2016;17:2151-2160 pubmed publisher
  8. Kadivar M, Petersson J, Svensson L, Marsal J. CD8??+ ?? T Cells: A Novel T Cell Subset with a Potential Role in Inflammatory Bowel Disease. J Immunol. 2016;197:4584-4592 pubmed
  9. Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
  10. Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
  11. Kilcollins A, Li J, Hsiao C, Wiemer A. HMBPP Analog Prodrugs Bypass Energy-Dependent Uptake To Promote Efficient BTN3A1-Mediated Malignant Cell Lysis by V?9V?2 T Lymphocyte Effectors. J Immunol. 2016;197:419-28 pubmed publisher
  12. Tanaka T, Yamamoto H, Elsayed A, Satou A, Asano N, Kohno K, et al. Clinicopathologic Spectrum of Gastrointestinal T-cell Lymphoma: Reappraisal Based on T-cell Receptor Immunophenotypes. Am J Surg Pathol. 2016;40:777-85 pubmed publisher
  13. Kim J, Choi Y, Lee B, Song M, Ban C, Kim J, et al. Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells. J Allergy Clin Immunol. 2016;137:1466-1476.e3 pubmed publisher
  14. Leong M, Newell E. Multiplexed Peptide-MHC Tetramer Staining with Mass Cytometry. Methods Mol Biol. 2015;1346:115-31 pubmed publisher
  15. Satou A, Asano N, Kato S, Katsuya H, Ishitsuka K, Elsayed A, et al. FoxP3-positive T cell lymphoma arising in non-HTLV1 carrier: clinicopathological analysis of 11 cases of PTCL-NOS and 2 cases of mycosis fungoides. Histopathology. 2016;68:1099-108 pubmed publisher
  16. Tomita S, Kikuti Y, Carreras J, Kojima M, Ando K, Takasaki H, et al. Genomic and immunohistochemical profiles of enteropathy-associated T-cell lymphoma in Japan. Mod Pathol. 2015;28:1286-96 pubmed publisher
  17. Owens G, Erickson K, Malone C, Pan C, Huynh M, Chang J, et al. Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis. J Neuroinflammation. 2015;12:134 pubmed publisher
  18. Wang Z, Wan Y, Qiu C, Quiñones Parra S, Zhu Z, Loh L, et al. Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8⁺ T cells. Nat Commun. 2015;6:6833 pubmed publisher
  19. Obiero J, Shekalaghe S, Hermsen C, Mpina M, Bijker E, Roestenberg M, et al. Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection. Infect Immun. 2015;83:2185-96 pubmed publisher
  20. Tsai C, Liong K, Gunalan M, Li N, Lim D, Fisher D, et al. Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virus. J Immunol. 2015;194:3890-900 pubmed publisher
  21. Kato S, Asano N, Miyata Takata T, Takata K, Elsayed A, Satou A, et al. T-cell receptor (TCR) phenotype of nodal Epstein-Barr virus (EBV)-positive cytotoxic T-cell lymphoma (CTL): a clinicopathologic study of 39 cases. Am J Surg Pathol. 2015;39:462-71 pubmed publisher
  22. Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
  23. Sun W, Wang Y, East J, Kimball A, Tkaczuk K, Kesmodel S, et al. Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional. Cytokine. 2015;72:48-57 pubmed publisher
  24. Li Z, Li W, Li N, Jiao Y, Chen D, Cui L, et al. γδ T cells are involved in acute HIV infection and associated with AIDS progression. PLoS ONE. 2014;9:e106064 pubmed publisher
  25. Davey M, Morgan M, Liuzzi A, Tyler C, Khan M, Szakmany T, et al. Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells. J Immunol. 2014;193:3704-3716 pubmed publisher
  26. Frencher J, Shen H, Yan L, Wilson J, Freitag N, Rizzo A, et al. HMBPP-deficient Listeria mutant immunization alters pulmonary/systemic responses, effector functions, and memory polarization of Vγ2Vδ2 T cells. J Leukoc Biol. 2014;96:957-67 pubmed publisher
  27. Hodara V, Parodi L, Chavez D, Smith L, Lanford R, Giavedoni L. Characterization of ??T cells in naïve and HIV-infected chimpanzees and their responses to T-cell activators in vitro. J Med Primatol. 2014;43:258-71 pubmed publisher
  28. Qin G, Mao H, Zheng J, Sia S, Liu Y, Chan P, et al. Phosphoantigen-expanded human gammadelta T cells display potent cytotoxicity against monocyte-derived macrophages infected with human and avian influenza viruses. J Infect Dis. 2009;200:858-65 pubmed publisher
  29. Conrad M, Davis W, Koop B. TCR and CD3 antibody cross-reactivity in 44 species. Cytometry A. 2007;71:925-33 pubmed
  30. Kalmbach Y, Boldt A, Fendel R, Mordmuller B, Kremsner P, Kun J. Increase in annexin V-positive B cells expressing LILRB1/ILT2/CD85j in malaria. Eur Cytokine Netw. 2006;17:175-80 pubmed
  31. Cairo C, Propp N, Hebbeler A, Colizzi V, Pauza C. The Vgamma2/Vdelta2 T-cell repertoire in Macaca fascicularis: functional responses to phosphoantigen stimulation by the Vgamma2/Jgamma1.2 subset. Immunology. 2005;115:197-205 pubmed
  32. Contamin H, Loizon S, Bourreau E, Michel J, Garraud O, Mercereau Puijalon O, et al. Flow cytometry identification and characterization of mononuclear cell subsets in the neotropical primate Saimiri sciureus (squirrel monkey). J Immunol Methods. 2005;297:61-71 pubmed
  33. Green A, Lissina A, Hutchinson S, Hewitt R, Temple B, James D, et al. Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin. Clin Exp Immunol. 2004;136:472-82 pubmed