This is a Validated Antibody Database (VAD) review about human TREK, based on 3 published articles (read how Labome selects the articles), using TREK antibody in all methods. It is aimed to help Labome visitors find the most suited TREK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TREK synonym: K2p2.1; TPKC1; TREK; TREK-1; TREK1; hTREK-1c; hTREK-1e

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal
  • immunocytochemistry knockout validation; mouse; 1:100; loading ...; fig 3b
  • immunohistochemistry; mouse; loading ...; fig 6a
Santa Cruz Biotechnology TREK antibody (Santa Cruz Biotechnology, sc-398449) was used in immunocytochemistry knockout validation on mouse samples at 1:100 (fig 3b) and in immunohistochemistry on mouse samples (fig 6a). Int J Mol Sci (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • immunocytochemistry knockout validation; mouse; 1:100; loading ...; fig 3b
  • immunohistochemistry; mouse; loading ...; fig 6a
Santa Cruz Biotechnology TREK antibody (Santa Cruz Biotechnology, sc-398449) was used in immunocytochemistry knockout validation on mouse samples at 1:100 (fig 3b) and in immunohistochemistry on mouse samples (fig 6a). Int J Mol Sci (2020) ncbi
mouse monoclonal
  • immunocytochemistry; human; 1:200; loading ...; fig 4b
In order to research the contribution of cochlin and mechanosensitive channel TREK-1 to the regulation of intraocular pressure, Santa Cruz Biotechnology TREK antibody (Santa Cruz, sc-398449) was used in immunocytochemistry on human samples at 1:200 (fig 4b). Sci Rep (2017) ncbi
mouse monoclonal
  • western blot; human; 1:200; loading ...; fig 7b
Santa Cruz Biotechnology TREK antibody (Santa Cruz, sc-398449) was used in western blot on human samples at 1:200 (fig 7b). Biochim Biophys Acta (2016) ncbi
Alomone Labs
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 6a
Alomone Labs TREK antibody (Alomone Labs, APC-047) was used in immunohistochemistry on mouse samples at 1:200 (fig 6a). Int J Mol Sci (2020) ncbi
Articles Reviewed
  1. Bae Y, Choi J, Ryoo K, Kim A, Kwon O, Jung H, et al. Spadin Modulates Astrocytic Passive Conductance via Inhibition of TWIK-1/TREK-1 Heterodimeric Channels. Int J Mol Sci. 2020;21: pubmed publisher
  2. Carreon T, Castellanos A, Gasull X, Bhattacharya S. Interaction of cochlin and mechanosensitive channel TREK-1 in trabecular meshwork cells influences the regulation of intraocular pressure. Sci Rep. 2017;7:452 pubmed publisher
  3. Sauter D, Sørensen C, Rapedius M, Brüggemann A, Novak I. pH-sensitive K(+) channel TREK-1 is a novel target in pancreatic cancer. Biochim Biophys Acta. 2016;1862:1994-2003 pubmed publisher