This is a Validated Antibody Database (VAD) review about human TRAP1, based on 14 published articles (read how Labome selects the articles), using TRAP1 antibody in all methods. It is aimed to help Labome visitors find the most suited TRAP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TRAP1 synonym: HSP 75; HSP75; HSP90L; TRAP-1; heat shock protein 75 kDa, mitochondrial; TNFR-associated protein 1; testicular tissue protein Li 209; tumor necrosis factor type 1 receptor-associated protein

Santa Cruz Biotechnology
mouse monoclonal (TR1)
  • immunoprecipitation; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology TRAP1 antibody (Santa Cruz, sc-13557) was used in immunoprecipitation on human samples (fig 2b) and in western blot on human samples (fig 2b). Nucleic Acids Res (2018) ncbi
mouse monoclonal (TR1)
  • western blot; human; loading ...; fig 4g
Santa Cruz Biotechnology TRAP1 antibody (SantaCruz, sc-13557) was used in western blot on human samples (fig 4g). Cell Death Dis (2016) ncbi
mouse monoclonal (42)
  • western blot; rat; 1:200
Santa Cruz Biotechnology TRAP1 antibody (Santa Cruz Biotechnology, sc-135944) was used in western blot on rat samples at 1:200. J Neurochem (2014) ncbi
mouse monoclonal (TR1)
  • western blot; human
Santa Cruz Biotechnology TRAP1 antibody (Santa Cruz Biotechnology, sc-13557) was used in western blot on human samples . Int J Oncol (2014) ncbi
Abcam
mouse monoclonal (Trap1-6)
  • immunocytochemistry; human; 1:200; loading ...; fig 3a
Abcam TRAP1 antibody (Abcam, ab2721) was used in immunocytochemistry on human samples at 1:200 (fig 3a). J Biol Chem (2017) ncbi
mouse monoclonal (Trap1-6)
  • western blot; human; loading ...; fig s2c
Abcam TRAP1 antibody (Abcam, ab2721) was used in western blot on human samples (fig s2c). FASEB J (2016) ncbi
mouse monoclonal (Trap1-6)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1b
Abcam TRAP1 antibody (Abcam, ab2721) was used in immunohistochemistry - paraffin section on human samples (fig 1a) and in western blot on human samples (fig 1b). J Mol Neurosci (2015) ncbi
mouse monoclonal (Trap1-6)
  • immunohistochemistry; human
Abcam TRAP1 antibody (Abcam, ab2721) was used in immunohistochemistry on human samples . Kidney Int (2014) ncbi
GeneTex
rabbit polyclonal
  • western blot; mouse; loading ...; fig 6i
  • western blot; human; fig 5a
GeneTex TRAP1 antibody (Immunoway, GTX102017) was used in western blot on mouse samples (fig 6i) and in western blot on human samples (fig 5a). Sci Rep (2017) ncbi
rabbit polyclonal
In order to develop reagents to study RNA binding proteins, GeneTex TRAP1 antibody (GeneTex, GTX102017) was used . Mol Cell (2016) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
Proteintech Group TRAP1 antibody (ProteinTech Group, 10325- AP) was used in western blot on mouse samples (fig 3a). J Gerontol A Biol Sci Med Sci (2017) ncbi
BD Biosciences
mouse monoclonal (42/Hsp75)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a, 1d
BD Biosciences TRAP1 antibody (BD BioSciences, 612345) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a, 1d). Diagn Pathol (2017) ncbi
mouse monoclonal (42/Hsp75)
  • western blot; mouse; 1:1000; fig 2
In order to study the alleviation of mitochondrial cardiomyopathy without affecting the mammalian UPRmt due to loss of CLPP, BD Biosciences TRAP1 antibody (BD Biosciences, 612344) was used in western blot on mouse samples at 1:1000 (fig 2). EMBO Rep (2016) ncbi
mouse monoclonal (42/Hsp75)
  • western blot; human; loading ...; fig 3b
BD Biosciences TRAP1 antibody (BD Biosciences, 612344) was used in western blot on human samples (fig 3b). J Biol Chem (2016) ncbi
Articles Reviewed
  1. Avolio R, Järvelin A, Mohammed S, Agliarulo I, Condelli V, Zoppoli P, et al. Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Res. 2018;46:12067-12086 pubmed publisher
  2. Xiao B, Goh J, Xiao L, Xian H, Lim K, Liou Y. Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin. J Biol Chem. 2017;292:16697-16708 pubmed publisher
  3. Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed publisher
  4. Pak M, Koh H, Roh M. Clinicopathologic significance of TRAP1 expression in colorectal cancer: a large scale study of human colorectal adenocarcinoma tissues. Diagn Pathol. 2017;12:6 pubmed publisher
  5. Amoroso M, Matassa D, Agliarulo I, Avolio R, Lu H, Sisinni L, et al. TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial-mesenchymal transition. Cell Death Dis. 2016;7:e2522 pubmed publisher
  6. Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed publisher
  7. Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed publisher
  8. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  9. Ghosh S, Shinogle H, Galeva N, Dobrowsky R, Blagg B. Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport. J Biol Chem. 2016;291:8309-23 pubmed publisher
  10. Roundhill E, Turnbull D, Burchill S. Localization of MRP-1 to the outer mitochondrial membrane by the chaperone protein HSP90β. FASEB J. 2016;30:1712-23 pubmed publisher
  11. Li S, Lv Q, Sun H, Xue Y, Wang P, Liu L, et al. Expression of TRAP1 predicts poor survival of malignant glioma patients. J Mol Neurosci. 2015;55:62-68 pubmed publisher
  12. Campos Martorell M, Salvador N, Monge M, Canals F, Garcia Bonilla L, Hernandez Guillamon M, et al. Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model. J Neurochem. 2014;130:301-12 pubmed publisher
  13. Sisinni L, Maddalena F, Lettini G, Condelli V, Matassa D, Esposito F, et al. TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells. Int J Oncol. 2014;44:573-82 pubmed publisher
  14. Saisawat P, Kohl S, Hilger A, Hwang D, Yung Gee H, Dworschak G, et al. Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association. Kidney Int. 2014;85:1310-7 pubmed publisher