This is a Validated Antibody Database (VAD) review about human TRAF2, based on 25 published articles (read how Labome selects the articles), using TRAF2 antibody in all methods. It is aimed to help Labome visitors find the most suited TRAF2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TRAF2 synonym: MGC:45012; RNF117; TRAP; TRAP3

Knockout validation
Abcam
domestic rabbit monoclonal (EPR6048)
  • western blot knockout validation; human; loading ...; fig 2a
Abcam TRAF2 antibody (Abcam, ab126758) was used in western blot knockout validation on human samples (fig 2a). Sci Adv (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 2a
Cell Signaling Technology TRAF2 antibody (Cell Signaling Technology, 4724) was used in western blot knockout validation on human samples (fig 2a). Sci Adv (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4724) was used in western blot knockout validation on mouse samples at 1:1000 (fig 3a). elife (2020) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; fig 3
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4712) was used in western blot knockout validation on human samples (fig 3). Cell Death Dis (2018) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1h
Cell Signaling Technology TRAF2 antibody (Cell signaling, 4724) was used in western blot knockout validation on human samples (fig 1h). Nature (2017) ncbi
Abcam
domestic rabbit monoclonal (EPR6048)
  • western blot; human; 1:1000; loading ...; fig 5c
Abcam TRAF2 antibody (Abcam, ab126758) was used in western blot on human samples at 1:1000 (fig 5c). Front Cell Dev Biol (2021) ncbi
domestic rabbit monoclonal (EPR6048)
  • western blot knockout validation; human; loading ...; fig 2a
Abcam TRAF2 antibody (Abcam, ab126758) was used in western blot knockout validation on human samples (fig 2a). Sci Adv (2021) ncbi
domestic rabbit monoclonal (EPR6048)
  • western blot; mouse; 1:1000; loading ...
Abcam TRAF2 antibody (Abcam, ab126758) was used in western blot on mouse samples at 1:1000. Mol Ther Nucleic Acids (2021) ncbi
domestic rabbit monoclonal (EPR6048)
  • western blot; mouse; loading ...; fig 3d
Abcam TRAF2 antibody (Abcam, Ab126758) was used in western blot on mouse samples (fig 3d). Cell (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-10)
  • western blot; human; loading ...; fig 5c
Santa Cruz Biotechnology TRAF2 antibody (Santa Cruz, sc-7346) was used in western blot on human samples (fig 5c). FASEB J (2018) ncbi
mouse monoclonal (F-2)
  • immunoprecipitation; human; fig 5d
  • western blot; human; fig 5d
Santa Cruz Biotechnology TRAF2 antibody (Santa Cruz Biotechnology, SC-136999) was used in immunoprecipitation on human samples (fig 5d) and in western blot on human samples (fig 5d). J Biol Chem (2017) ncbi
mouse monoclonal (H-10)
  • immunoprecipitation; human; fig 3b
  • western blot; human; 1:1000; fig 3b
Santa Cruz Biotechnology TRAF2 antibody (Santa Cruz, sc-7346) was used in immunoprecipitation on human samples (fig 3b) and in western blot on human samples at 1:1000 (fig 3b). Front Pharmacol (2016) ncbi
mouse monoclonal (F-2)
  • western blot; rat; loading ...; fig 3a
Santa Cruz Biotechnology TRAF2 antibody (Santa Cruz Biotechnology, SC-136999) was used in western blot on rat samples (fig 3a). PLoS ONE (2016) ncbi
mouse monoclonal (H-10)
  • immunoprecipitation; mouse; fig 3
  • western blot; mouse; fig 3
In order to study the function of the PHD motif of MEKK1, Santa Cruz Biotechnology TRAF2 antibody (Santa Cruz Biotechnology, sc-7346) was used in immunoprecipitation on mouse samples (fig 3) and in western blot on mouse samples (fig 3). EMBO J (2014) ncbi
Enzo Life Sciences
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Enzo Life Sciences TRAF2 antibody (Enzo life sciences, ADI-AAP-422) was used in western blot on human samples (fig 2a). EMBO J (2017) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 2a
Cell Signaling Technology TRAF2 antibody (Cell Signaling Technology, 4724) was used in western blot knockout validation on human samples (fig 2a). Sci Adv (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology TRAF2 antibody (Cell Signaling Technology, 4724) was used in western blot on human samples at 1:1000 (fig 1e). Signal Transduct Target Ther (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4724) was used in western blot knockout validation on mouse samples at 1:1000 (fig 3a). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology TRAF2 antibody (Cell Signaling Technology, 4724) was used in western blot on mouse samples at 1:1000 (fig 5a). J Cell Sci (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s9c
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4724) was used in western blot on mouse samples at 1:1000 (fig s9c). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4724) was used in western blot on mouse samples (fig 1b). Cell Death Dis (2018) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; fig 3
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4712) was used in western blot knockout validation on human samples (fig 3). Cell Death Dis (2018) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1h
Cell Signaling Technology TRAF2 antibody (Cell signaling, 4724) was used in western blot knockout validation on human samples (fig 1h). Nature (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2a
In order to elucidate how high-risk human papillomavirus alters signaling pathways involved in cell death and growth regulation, Cell Signaling Technology TRAF2 antibody (Cell signaling, 4724s) was used in western blot on human samples (fig 2a). Front Immunol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1a
In order to explore how hepatitis C virus depletes TRAF6 from its host cells, Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4712) was used in western blot on human samples (fig 1a). J Virol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology TRAF2 antibody (CST, 4712) was used in western blot on human samples (fig 4b). Nat Microbiol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4724) was used in western blot on mouse samples (fig 5). Cell Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology TRAF2 antibody (Cell Signaling, 4712) was used in western blot on mouse samples (fig 4b). PLoS ONE (2016) ncbi
BD Biosciences
mouse monoclonal (C90-481)
  • western blot; human; fig 6
BD Biosciences TRAF2 antibody (BD Biosciences, 558890) was used in western blot on human samples (fig 6). Oncotarget (2015) ncbi
mouse monoclonal (C90-481)
  • immunocytochemistry; human
BD Biosciences TRAF2 antibody (Pharmingen, 558890) was used in immunocytochemistry on human samples . Oncotarget (2015) ncbi
mouse monoclonal (C90-481)
  • western blot; human
BD Biosciences TRAF2 antibody (BD Biosciences, 558890) was used in western blot on human samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Tao H, Liao Y, Yan Y, He Z, Zhou J, Wang X, et al. BRCC3 Promotes Tumorigenesis of Bladder Cancer by Activating the NF-κB Signaling Pathway Through Targeting TRAF2. Front Cell Dev Biol. 2021;9:720349 pubmed publisher
  2. Liu J, Hideshima T, Xing L, Wang S, Zhou W, Samur M, et al. ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment. Sci Adv. 2021;7: pubmed publisher
  3. Zhang Z, Wen H, Peng B, Weng J, Zeng F. HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis. Mol Ther Nucleic Acids. 2021;24:711-727 pubmed publisher
  4. Guo G, Gao M, Gao X, Zhu B, Huang J, Luo K, et al. SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response. Signal Transduct Target Ther. 2021;6:119 pubmed publisher
  5. Hinte F, van Anken E, Tirosh B, Brune W. Repression of viral gene expression and replication by the unfolded protein response effector XBP1u. elife. 2020;9: pubmed publisher
  6. Vredevoogd D, Kuilman T, Ligtenberg M, Boshuizen J, Stecker K, de Bruijn B, et al. Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold. Cell. 2019;178:585-599.e15 pubmed publisher
  7. Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
  8. Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, et al. Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation. Nat Commun. 2019;10:1801 pubmed publisher
  9. Siegmund D, Ehrenschwender M, Wajant H. TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling. Cell Death Dis. 2018;9:921 pubmed publisher
  10. Yang C, Chiu L, Chang C, Chuang H, Tan T. Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation. FASEB J. 2018;:fj201800244RR pubmed publisher
  11. Makhov P, Naito S, Haifler M, Kutikov A, Boumber Y, Uzzo R, et al. The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma. Cell Death Dis. 2018;9:374 pubmed publisher
  12. Wu G, Mu T, Gao Z, Wang J, Sy M, Li C. Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production. J Biol Chem. 2017;292:18747-18759 pubmed publisher
  13. Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed publisher
  14. Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
  15. Lin C, Lin W, Cho R, Wang C, Hsiao L, Yang C. TNF-?-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-?B Cascade on Human Pulmonary Alveolar Epithelial Cells. Front Pharmacol. 2016;7:447 pubmed
  16. Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed
  17. Chan S, Lee J, Narula M, Ou J. Suppression of Host Innate Immune Response by Hepatitis C Virus via Induction of Autophagic Degradation of TRAF6. J Virol. 2016;90:10928-10935 pubmed publisher
  18. de Jong M, Liu Z, Chen D, Alto N. Shigella flexneri suppresses NF-?B activation by inhibiting linear ubiquitin chain ligation. Nat Microbiol. 2016;1:16084 pubmed publisher
  19. Stucky A, Bakshi K, Friedman E, Wang H. Prenatal Cocaine Exposure Upregulates BDNF-TrkB Signaling. PLoS ONE. 2016;11:e0160585 pubmed publisher
  20. Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
  21. Li J, Chen K, Li S, Liu T, Wang F, Xia Y, et al. Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis. PLoS ONE. 2016;11:e0152570 pubmed publisher
  22. Oh Y, Yue P, Wang D, Tong J, Chen Z, Khuri F, et al. Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling. Oncotarget. 2015;6:41324-38 pubmed publisher
  23. Ren H, Wang J, Yang F, Zhang X, Wang A, Sun L, et al. Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer. Oncotarget. 2015;6:4080-96 pubmed
  24. Charlaftis N, Suddason T, Wu X, Anwar S, Karin M, Gallagher E. The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines. EMBO J. 2014;33:2581-96 pubmed publisher
  25. Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed publisher