This is a Validated Antibody Database (VAD) review about human TPX2, based on 11 published articles (read how Labome selects the articles), using TPX2 antibody in all methods. It is aimed to help Labome visitors find the most suited TPX2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TPX2 synonym: C20orf1; C20orf2; DIL-2; DIL2; FLS353; GD:C20orf1; HCA519; HCTP4; REPP86; p100

Abcam
mouse monoclonal (18D5-1)
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 1a
Abcam TPX2 antibody (Abcam, ab32795) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 1a). Mol Ther Nucleic Acids (2020) ncbi
mouse monoclonal (18D5-1)
  • western blot; human; loading ...; fig 6b
Abcam TPX2 antibody (Abcam, ab32795) was used in western blot on human samples (fig 6b). J Cell Biol (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:1000; loading ...; fig 6a
  • western blot; human; loading ...; fig 6g
Novus Biologicals TPX2 antibody (Novus, mb500179) was used in immunocytochemistry on human samples at 1:1000 (fig 6a) and in western blot on human samples (fig 6g). Mol Cancer Res (2018) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 3
Novus Biologicals TPX2 antibody (Acris Antibodies GmbH, NB500-179) was used in immunocytochemistry on human samples (fig 3). Int J Oncol (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:1000; fig 4
In order to elucidate the spindle proteome that is clathirin-dependent, Novus Biologicals TPX2 antibody (Novus Biologicals, NB500-179) was used in immunocytochemistry on human samples at 1:1000 (fig 4). Mol Cell Proteomics (2016) ncbi
domestic rabbit polyclonal
In order to identify microtubule-associated proteins that interact with ch-TOG to regulate bipolar spindle assembly in human cells, Novus Biologicals TPX2 antibody (Novus, NB500-179) was used . Sci Rep (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-5)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 2d
Santa Cruz Biotechnology TPX2 antibody (Santa Cruz, sc-376812) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 2d). World J Surg Oncol (2017) ncbi
mouse monoclonal (18D5)
  • western blot; human; 1:1000; fig 3
Santa Cruz Biotechnology TPX2 antibody (Santa Cruz, 18D5) was used in western blot on human samples at 1:1000 (fig 3). Cell Cycle (2015) ncbi
Proteintech Group
domestic rabbit polyclonal
Proteintech Group TPX2 antibody (Proteintech, 11741-1-AP) was used . J Cell Sci (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2R5C)
  • western blot; human; 1:1000; loading ...; fig 4d
Cell Signaling Technology TPX2 antibody (Cell Signaling, 12245) was used in western blot on human samples at 1:1000 (fig 4d). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D2R5C)
  • western blot; human
Cell Signaling Technology TPX2 antibody (Cell Signaling Technology, 12245) was used in western blot on human samples . J Proteome Res (2015) ncbi
Articles Reviewed
  1. Feng C, Zhang H, Zeng A, Bai M, Wang X. Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma. Mol Ther Nucleic Acids. 2020;20:186-195 pubmed publisher
  2. Lin C, Kitagawa M, Tang X, Hou M, Wu J, Qu D, et al. CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. Nat Commun. 2018;9:1039 pubmed publisher
  3. Chu T, Connell M, Zhou L, He Z, Won J, Chen H, et al. Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A. Mol Cancer Res. 2018;16:16-31 pubmed publisher
  4. Schneider M, Christopoulos P, Muley T, Warth A, Klingmueller U, Thomas M, et al. AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients. Int J Oncol. 2017;50:365-372 pubmed publisher
  5. Tomii C, Inokuchi M, Takagi Y, Ishikawa T, Otsuki S, Uetake H, et al. TPX2 expression is associated with poor survival in gastric cancer. World J Surg Oncol. 2017;15:14 pubmed publisher
  6. Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed publisher
  7. Hu M, Wang Z, Teng Y, Jiang Z, Ma X, Hou N, et al. Loss of protein phosphatase 6 in oocytes causes failure of meiosis II exit and impaired female fertility. J Cell Sci. 2015;128:3769-80 pubmed publisher
  8. Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, et al. The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells. J Cell Biol. 2015;210:209-24 pubmed publisher
  9. Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed publisher
  10. Xu H, Dephoure N, Sun H, Zhang H, Fan F, Liu J, et al. Proteomic Profiling of Paclitaxel Treated Cells Identifies a Novel Mechanism of Drug Resistance Mediated by PDCD4. J Proteome Res. 2015;14:2480-91 pubmed publisher
  11. Stolz A, Ertych N, Bastians H. A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientation. Cell Cycle. 2015;14:827-37 pubmed publisher