This is a Validated Antibody Database (VAD) review about human TOX, based on 7 published articles (read how Labome selects the articles), using TOX antibody in all methods. It is aimed to help Labome visitors find the most suited TOX antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TOX synonym: TOX1

Invitrogen
rat monoclonal (TXRX10)
  • flow cytometry; mouse; 1:100; fig 2f
Invitrogen TOX antibody (Ebioscience, TXRX10) was used in flow cytometry on mouse samples at 1:100 (fig 2f). Nat Commun (2021) ncbi
rat monoclonal (TXRX10)
  • flow cytometry; mouse; fig s6f
Invitrogen TOX antibody (eBioscience, TXRX10) was used in flow cytometry on mouse samples (fig s6f). Nature (2019) ncbi
rat monoclonal (TXRX10)
  • western blot; mouse; loading ...; fig 6j
Invitrogen TOX antibody (eBioscience, TXRX10) was used in western blot on mouse samples (fig 6j). Nature (2019) ncbi
rat monoclonal (TXRX10)
  • flow cytometry; mouse; loading ...; fig 3f
Invitrogen TOX antibody (eBioscience, TXRX10) was used in flow cytometry on mouse samples (fig 3f). Front Immunol (2018) ncbi
rat monoclonal (TXRX10)
  • flow cytometry; mouse; loading ...; fig 5d
Invitrogen TOX antibody (eBioscience, TXRX10) was used in flow cytometry on mouse samples (fig 5d). J Exp Med (2018) ncbi
Miltenyi Biotec
human monoclonal (REA473)
  • flow cytometry; human; loading ...; fig s9d
Miltenyi Biotec TOX antibody (Miltenyi Biotec, 130-118-335) was used in flow cytometry on human samples (fig s9d). Science (2021) ncbi
human monoclonal (REA473)
  • flow cytometry; human; 1:50; loading ...
Miltenyi Biotec TOX antibody (Miltenyi, 130-120-716) was used in flow cytometry on human samples at 1:50. bioRxiv (2020) ncbi
human monoclonal (REA473)
  • flow cytometry; human; loading ...; fig 2a
Miltenyi Biotec TOX antibody (Miltenyi Biotec, REA473) was used in flow cytometry on human samples (fig 2a). Nature (2019) ncbi
Abcam
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 6j
Abcam TOX antibody (Abcam, ab155768) was used in immunoprecipitation on mouse samples (fig 6j). Nature (2019) ncbi
Articles Reviewed
  1. Weber E, Parker K, Sotillo E, Lynn R, Anbunathan H, Lattin J, et al. Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling. Science. 2021;372: pubmed publisher
  2. Page N, Lemeille S, Vincenti I, Klimek B, Mariotte A, Wagner I, et al. Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling. Nat Commun. 2021;12:1009 pubmed publisher
  3. Mathew D, Giles J, Baxter A, Greenplate A, Wu J, Alanio C, et al. Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions. bioRxiv. 2020;: pubmed publisher
  4. Wei J, Long L, Zheng W, Dhungana Y, Lim S, Guy C, et al. Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. Nature. 2019;576:471-476 pubmed publisher
  5. Khan O, Giles J, McDonald S, Manne S, Ngiow S, Patel K, et al. TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion. Nature. 2019;: pubmed publisher
  6. Li J, He Y, Hao J, Ni L, Dong C. High Levels of Eomes Promote Exhaustion of Anti-tumor CD8+ T Cells. Front Immunol. 2018;9:2981 pubmed publisher
  7. Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018;215:249-262 pubmed publisher