This is a Validated Antibody Database (VAD) review about human TNPO1, based on 26 published articles (read how Labome selects the articles), using TNPO1 antibody in all methods. It is aimed to help Labome visitors find the most suited TNPO1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TNPO1 synonym: IPO2; KPNB2; MIP; MIP1; TRN

Abcam
mouse monoclonal (D45)
  • western blot; human; loading ...; fig 2c
Abcam TNPO1 antibody (Abcam, ab10303) was used in western blot on human samples (fig 2c). Mol Cell (2019) ncbi
mouse monoclonal (D45)
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; 1:3000; loading ...; fig 4a
Abcam TNPO1 antibody (Abcam, ab10303) was used in immunocytochemistry on human samples (fig 4b) and in western blot on human samples at 1:3000 (fig 4a). J Cell Sci (2016) ncbi
mouse monoclonal (D45)
  • western blot; mouse; 1:1000; fig 6
  • western blot; human; 1:1000; fig 6
Abcam TNPO1 antibody (Abcam, ab10303) was used in western blot on mouse samples at 1:1000 (fig 6) and in western blot on human samples at 1:1000 (fig 6). PLoS ONE (2016) ncbi
mouse monoclonal (D45)
  • western blot; mouse; 1:1000; fig 1
In order to investigate the impact of Tmem65 on heart development, Abcam TNPO1 antibody (Abcam, ab10303) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
mouse monoclonal (D45)
  • immunocytochemistry; human; 1:100
In order to study the effect of loss of Transactive response DNA-binding protein 43 on the proteome, Abcam TNPO1 antibody (Abcam, ab10303) was used in immunocytochemistry on human samples at 1:100. Neuroscience (2015) ncbi
mouse monoclonal (D45)
  • western blot; human
Abcam TNPO1 antibody (Abcam, ab10303) was used in western blot on human samples . Antioxid Redox Signal (2015) ncbi
mouse monoclonal (D45)
  • western blot; human
Abcam TNPO1 antibody (Abcam, ab10303) was used in western blot on human samples . PLoS ONE (2012) ncbi
Novus Biologicals
mouse monoclonal (D45)
  • western blot; mouse; 1:1000; loading ...; fig e4a
Novus Biologicals TNPO1 antibody (Novus, NB600-1397) was used in western blot on mouse samples at 1:1000 (fig e4a). Nat Med (2022) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-11)
  • western blot; human; fig 1, 5, 6
Santa Cruz Biotechnology TNPO1 antibody (Santa Cruz Biotechnology, sc-365179) was used in western blot on human samples (fig 1, 5, 6). J Biol Chem (2015) ncbi
BD Biosciences
mouse monoclonal (36/Transportin)
  • western blot; human; 1:1000; loading ...; fig 4c
BD Biosciences TNPO1 antibody (BD Bioscience, 558660) was used in western blot on human samples at 1:1000 (fig 4c). elife (2020) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; loading ...; fig 1g
BD Biosciences TNPO1 antibody (BD Biosciences, 550078) was used in flow cytometry on human samples (fig 1g). Cell (2019) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; loading ...; fig 6c
BD Biosciences TNPO1 antibody (BD, D21-1351) was used in flow cytometry on human samples (fig 6c). J Exp Med (2017) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; African green monkey; fig s2b
In order to optimize the dosing regimen of neutralizing anti-HIV-1 antibodies, BD Biosciences TNPO1 antibody (BD Biosciences, D21-1351) was used in flow cytometry on African green monkey samples (fig s2b). Nature (2017) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; loading ...; tbl 1
In order to demonstrate that freezing already-stained samples suspended in 10% DMSO in FBS is practical and efficient way to preserve already-stained samples for mass cytometry assessment, BD Biosciences TNPO1 antibody (BD Biosciences, D21-1351) was used in flow cytometry on human samples (tbl 1). Cytometry A (2017) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; loading ...; fig s3a
BD Biosciences TNPO1 antibody (BD Biosciences, 550078) was used in flow cytometry on human samples (fig s3a). Cell (2016) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; rhesus macaque; loading ...; fig 1b
BD Biosciences TNPO1 antibody (BD Biosciences, D21-1351) was used in flow cytometry on rhesus macaque samples (fig 1b). J Virol (2016) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; fig 2
BD Biosciences TNPO1 antibody (BD Bioscience, 550078) was used in flow cytometry on human samples (fig 2). Oncoimmunology (2016) ncbi
mouse monoclonal (D21-1351)
  • mass cytometry; human; loading ...; tbl 1, 3
In order to use elemental metal isotopes conjugated to monoclonal antibodies and study intracellular functional markers and surface phenotypic markers on natural killer cells, BD Biosciences TNPO1 antibody (BD Biosciences, D21-1352) was used in mass cytometry on human samples (tbl 1, 3). Methods Mol Biol (2016) ncbi
mouse monoclonal (11A3)
  • flow cytometry; human; fig 6
BD Biosciences TNPO1 antibody (BD, 554730) was used in flow cytometry on human samples (fig 6). J Exp Med (2015) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; fig 6
BD Biosciences TNPO1 antibody (BD, 560565) was used in flow cytometry on human samples (fig 6). J Exp Med (2015) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; 4:100; fig s1
In order to show that hepatitis B virus exposure in utero enhances immunity to bacterial infections, BD Biosciences TNPO1 antibody (Becton Dickinson, D21-1351) was used in flow cytometry on human samples at 4:100 (fig s1). Nat Commun (2015) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; fig 3
BD Biosciences TNPO1 antibody (BD Biosciences, D21-1351) was used in flow cytometry on human samples (fig 3). J Immunol (2015) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human
BD Biosciences TNPO1 antibody (BD Pharmingen, D21-1351) was used in flow cytometry on human samples . J Infect Dis (2015) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human
BD Biosciences TNPO1 antibody (BD Bioscience, D21-1351) was used in flow cytometry on human samples . Proc Natl Acad Sci U S A (2014) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; rhesus macaque; loading ...; fig 5b
In order to explore germinal center-related hyperimmune responses and disease severity during viral infection, BD Biosciences TNPO1 antibody (BD, D21-1351) was used in flow cytometry on rhesus macaque samples (fig 5b). J Immunol (2014) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human
BD Biosciences TNPO1 antibody (BD Pharmingen, D21-1351) was used in flow cytometry on human samples . J Virol (2014) ncbi
mouse monoclonal (D21-1351)
  • flow cytometry; human; loading ...; fig 1
In order to discuss the importance of assessing immune competence in cancer patients, BD Biosciences TNPO1 antibody (BD, D21-1351) was used in flow cytometry on human samples (fig 1). Cancer Immunol Immunother (2014) ncbi
Articles Reviewed
  1. Korobeynikov V, Lyashchenko A, Blanco Redondo B, Jafar Nejad P, Shneider N. Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis. Nat Med. 2022;28:104-116 pubmed publisher
  2. Hayes L, Duan L, Bowen K, Kalab P, Rothstein J. C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import. elife. 2020;9: pubmed publisher
  3. Jennewein M, Goldfarb I, Dolatshahi S, Cosgrove C, Noelette F, Krykbaeva M, et al. Fc Glycan-Mediated Regulation of Placental Antibody Transfer. Cell. 2019;: pubmed publisher
  4. Modic M, Grosch M, Rot G, Schirge S, Lepko T, Yamazaki T, et al. Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Mol Cell. 2019;74:951-965.e13 pubmed publisher
  5. Djaoud Z, Guethlein L, Horowitz A, Azzi T, Nemat Gorgani N, Olive D, et al. Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and ?? T cells. J Exp Med. 2017;214:1827-1841 pubmed publisher
  6. Nishimura Y, Gautam R, Chun T, Sadjadpour R, Foulds K, Shingai M, et al. Early antibody therapy can induce long-lasting immunity to SHIV. Nature. 2017;543:559-563 pubmed publisher
  7. Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
  8. Lu L, Chung A, Rosebrock T, Ghebremichael M, Yu W, Grace P, et al. A Functional Role for Antibodies in Tuberculosis. Cell. 2016;167:433-443.e14 pubmed publisher
  9. Madugula V, Lu L. A ternary complex comprising transportin1, Rab8 and the ciliary targeting signal directs proteins to ciliary membranes. J Cell Sci. 2016;129:3922-3934 pubmed
  10. Torrado B, Grana M, Badano J, Irigoín F. Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent. PLoS ONE. 2016;11:e0162033 pubmed publisher
  11. Ayala V, Trivett M, Barsov E, Jain S, Piatak M, Trubey C, et al. Adoptive Transfer of Engineered Rhesus Simian Immunodeficiency Virus-Specific CD8+ T Cells Reduces the Number of Transmitted/Founder Viruses Established in Rhesus Macaques. J Virol. 2016;90:9942-9952 pubmed publisher
  12. Peper J, Bösmüller H, Schuster H, Gückel B, Hörzer H, Roehle K, et al. HLA ligandomics identifies histone deacetylase 1 as target for ovarian cancer immunotherapy. Oncoimmunology. 2016;5:e1065369 pubmed publisher
  13. Kay A, Strauss Albee D, Blish C. Application of Mass Cytometry (CyTOF) for Functional and Phenotypic Analysis of Natural Killer Cells. Methods Mol Biol. 2016;1441:13-26 pubmed publisher
  14. Sharma P, Abbasi C, Lazic S, Teng A, Wang D, Dubois N, et al. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015;6:8391 pubmed publisher
  15. Hwang B, McCool K, Wan J, Wuerzberger Davis S, Young E, Choi E, et al. IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation. J Biol Chem. 2015;290:17967-84 pubmed publisher
  16. Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, et al. Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia. J Exp Med. 2015;212:939-51 pubmed publisher
  17. Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher
  18. Å talekar M, Yin X, Rebolj K, Darovic S, Troakes C, Mayr M, et al. Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport. Neuroscience. 2015;293:157-70 pubmed publisher
  19. Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson M, Kekäläinen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol. 2015;194:2467-71 pubmed publisher
  20. Boltjes A, van Montfoort N, Biesta P, Op den Brouw M, Kwekkeboom J, van der Laan L, et al. Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function. J Infect Dis. 2015;211:1268-78 pubmed publisher
  21. Hu H, Eller M, Zafar S, Zhou Y, Gu M, Wei Z, et al. Preferential infection of human Ad5-specific CD4 T cells by HIV in Ad5 naturally exposed and recombinant Ad5-HIV vaccinated individuals. Proc Natl Acad Sci U S A. 2014;111:13439-44 pubmed publisher
  22. Putker M, Vos H, van Dorenmalen K, de Ruiter H, Duran A, Snel B, et al. Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling. Antioxid Redox Signal. 2015;22:15-28 pubmed publisher
  23. Hong J, Amancha P, Rogers K, Courtney C, Havenar Daughton C, Crotty S, et al. Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection. J Immunol. 2014;193:797-806 pubmed publisher
  24. Payne T, Blackinton J, Frisbee A, Pickeral J, Sawant S, Vandergrift N, et al. Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. J Virol. 2014;88:9514-28 pubmed publisher
  25. Chang S, Kohrt H, Maecker H. Monitoring the immune competence of cancer patients to predict outcome. Cancer Immunol Immunother. 2014;63:713-9 pubmed publisher
  26. Jarboui M, Bidoia C, Woods E, Roe B, Wynne K, Elia G, et al. Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. PLoS ONE. 2012;7:e48702 pubmed publisher