This is a Validated Antibody Database (VAD) review about human TNK2, based on 4 published articles (read how Labome selects the articles), using TNK2 antibody in all methods. It is aimed to help Labome visitors find the most suited TNK2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TNK2 synonym: ACK; ACK-1; ACK1; p21cdc42Hs

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (A-11)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 7b
  • western blot knockout validation; human; 1:1000; loading ...; fig 1a
Santa Cruz Biotechnology TNK2 antibody (Santa Cruz, sc-28336) was used in western blot knockout validation on mouse samples at 1:1000 (fig 7b) and in western blot knockout validation on human samples at 1:1000 (fig 1a). elife (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-11)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 7b
  • western blot knockout validation; human; 1:1000; loading ...; fig 1a
Santa Cruz Biotechnology TNK2 antibody (Santa Cruz, sc-28336) was used in western blot knockout validation on mouse samples at 1:1000 (fig 7b) and in western blot knockout validation on human samples at 1:1000 (fig 1a). elife (2019) ncbi
mouse monoclonal (A-11)
  • western blot; human; loading ...; fig 1c
In order to study the role of ACK1/TNK2 in histone H4 Tyr88-phosphorylation and androgen receptor expression in prostate cancer, Santa Cruz Biotechnology TNK2 antibody (SantaCruz, SC-28336) was used in western blot on human samples (fig 1c). Cancer Cell (2017) ncbi
mouse monoclonal (A-11)
  • western blot; human
Santa Cruz Biotechnology TNK2 antibody (Santa Cruz, sc-28336) was used in western blot on human samples . J Biol Chem (2013) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology TNK2 antibody (CST, 3138) was used in western blot on human samples at 1:1000. Cell Death Dis (2016) ncbi
Articles Reviewed
  1. Jiang H, Leung C, Tahan S, Wang D. Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1. elife. 2019;8: pubmed publisher
  2. Mahajan K, Malla P, Lawrence H, Chen Z, Kumar Sinha C, Malik R, et al. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017;31:790-803.e8 pubmed publisher
  3. Anta B, Pérez Rodríguez A, Castro J, García Domínguez C, Ibiza S, Martínez N, et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death Dis. 2016;7:e2311 pubmed publisher
  4. Linderoth E, Pilia G, Mahajan N, Ferby I. Activated Cdc42-associated kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell death. J Biol Chem. 2013;288:32922-31 pubmed publisher