This is a Validated Antibody Database (VAD) review about human TMEM119, based on 32 published articles (read how Labome selects the articles), using TMEM119 antibody in all methods. It is aimed to help Labome visitors find the most suited TMEM119 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TMEM119 synonym: OBIF

Abcam
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2b
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 2b). Theranostics (2022) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 1b
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 1b). Proc Natl Acad Sci U S A (2022) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 5b
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 5b). Front Immunol (2022) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3c
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry on mouse samples at 1:500 (fig 3c). Proc Natl Acad Sci U S A (2022) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8a
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 8a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (106-6)
  • flow cytometry; mouse; loading ...; fig 4b
Abcam TMEM119 antibody (Abcam, ab225496) was used in flow cytometry on mouse samples (fig 4b). Nat Commun (2021) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry; human; 1:200; loading ...; fig s1f
Abcam TMEM119 antibody (Abcam, AB209064) was used in immunohistochemistry on human samples at 1:200 (fig s1f). Nat Immunol (2021) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; loading ...; fig s4h
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples (fig s4h). Neuron (2021) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2e
Abcam TMEM119 antibody (abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2e). Acta Neuropathol Commun (2021) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 3g
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 3g). elife (2020) ncbi
domestic rabbit monoclonal (106-6)
  • flow cytometry; mouse; 1:100; loading ...; fig 1d
Abcam TMEM119 antibody (Abcam, 101-6) was used in flow cytometry on mouse samples at 1:100 (fig 1d). elife (2020) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7b
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry on mouse samples at 1:100 (fig 7b). elife (2020) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig 7
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - free floating section on mouse samples at 1:200 (fig 7). elife (2020) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry; mouse; 1:100; loading ...; fig s4d
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry on mouse samples at 1:100 (fig s4d). Nat Commun (2020) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig s13b
Abcam TMEM119 antibody (Abcam, AB209064) was used in immunohistochemistry - frozen section on mouse samples at 1:400 (fig s13b). Sci Adv (2020) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4a
Abcam TMEM119 antibody (Abcam, 28-3) was used in immunohistochemistry - paraffin section on mouse samples (fig 4a). Acta Neuropathol (2020) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 3s2c
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 3s2c). elife (2019) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; 1:5000; loading ...; fig 1u
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples at 1:5000 (fig 1u). J Comp Neurol (2020) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5f
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 5f). Nat Commun (2019) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - free floating section; mouse; 1:100; loading ...; fig 1f
Abcam TMEM119 antibody (Abcam, 28-3) was used in immunohistochemistry - free floating section on mouse samples at 1:100 (fig 1f). Nature (2019) ncbi
domestic rabbit monoclonal (106-6)
  • immunohistochemistry - frozen section; mouse; 1,000 ug/ml; loading ...; fig 3e
Abcam TMEM119 antibody (Abcam, 106-6) was used in immunohistochemistry - frozen section on mouse samples at 1,000 ug/ml (fig 3e). Science (2019) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4e
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry on mouse samples at 1:100 (fig 4e). elife (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1a
Abcam TMEM119 antibody (Abcam, ab185333) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1a). J Cell Biol (2019) ncbi
domestic rabbit monoclonal (106-6)
  • flow cytometry; mouse; 1:400; loading ...; fig s1a
Abcam TMEM119 antibody (Abcam, ab210405) was used in flow cytometry on mouse samples at 1:400 (fig s1a). Neuron (2019) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry - frozen section; mouse; loading ...; fig s2a
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry - frozen section on mouse samples (fig s2a). J Exp Med (2018) ncbi
domestic rabbit monoclonal (28-3)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5a
Abcam TMEM119 antibody (Abcam, ab209064) was used in immunohistochemistry on mouse samples at 1:100 (fig 5a). J Neurosci (2018) ncbi
Synaptic Systems
mouse monoclonal (195H4)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s7b
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1e
Synaptic Systems TMEM119 antibody (Synaptic Systems, 400011) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig s7b) and in immunohistochemistry on mouse samples at 1:200 (fig 1e). Acta Neuropathol Commun (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 2d
Synaptic Systems TMEM119 antibody (Synaptic system, 400002) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2d). Front Pharmacol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 2a
Synaptic Systems TMEM119 antibody (Synaptic Systems, 400002) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 2a). FASEB J (2019) ncbi
BioLegend
mouse monoclonal (A16075D)
  • immunohistochemistry - frozen section; human; 1:200; fig 4b
BioLegend TMEM119 antibody (BioLegend, 853302) was used in immunohistochemistry - frozen section on human samples at 1:200 (fig 4b). Front Cell Neurosci (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:400; loading ...; fig 6b
Invitrogen TMEM119 antibody (Thermo Fisher, PA5-62505) was used in western blot on mouse samples at 1:400 (fig 6b). Acta Neuropathol Commun (2021) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:3000; loading ...; fig 4a
MilliporeSigma TMEM119 antibody (Sigma-Aldrich, HPA051870) was used in immunohistochemistry - paraffin section on human samples at 1:3000 (fig 4a). Neuropathol Appl Neurobiol (2019) ncbi
Articles Reviewed
  1. Shi H, Yin Z, Koronyo Y, Fuchs D, Sheyn J, Davis M, et al. Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia. Acta Neuropathol Commun. 2022;10:136 pubmed publisher
  2. Li J, Chordia M, Zhang Y, Zong H, Pan D, Zuo Z. Critical role of FPR1 in splenocyte migration into brain to worsen inflammation and ischemic brain injury in mice. Theranostics. 2022;12:3024-3044 pubmed publisher
  3. Zhao Q, Dai W, Chen H, Jacobs R, Zlokovic B, Lund B, et al. Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation. Proc Natl Acad Sci U S A. 2022;119:e2113310119 pubmed publisher
  4. Abbas Z, GEORGE C, Ancliffe M, Howlett M, Jones A, Kuchibhotla M, et al. Conventional Therapies Deplete Brain-Infiltrating Adaptive Immune Cells in a Mouse Model of Group 3 Medulloblastoma Implicating Myeloid Cells as Favorable Immunotherapy Targets. Front Immunol. 2022;13:837013 pubmed publisher
  5. Guo X, Kimura A, Namekata K, Harada C, Arai N, Takeda K, et al. ASK1 signaling regulates phase-specific glial interactions during neuroinflammation. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
  6. Kettwig M, Ternka K, Wendland K, Krüger D, Zampar S, Schob C, et al. Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy. Nat Commun. 2021;12:6530 pubmed publisher
  7. Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, et al. Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration. Front Pharmacol. 2021;12:729524 pubmed publisher
  8. Guo D, Yamamoto M, Hernandez C, Khodadadi H, Baban B, Stranahan A. Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice. Nat Commun. 2021;12:4623 pubmed publisher
  9. Bodnar B, Zhang Y, Liu J, Lin Y, Wang P, Wei Z, et al. Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells. Front Cell Neurosci. 2021;15:682272 pubmed publisher
  10. Emre C, Do K, Jun B, Hjorth E, Alcalde S, Kautzmann M, et al. Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:116 pubmed publisher
  11. Huang Y, Happonen K, Burrola P, O Connor C, Hah N, Huang L, et al. Microglia use TAM receptors to detect and engulf amyloid β plaques. Nat Immunol. 2021;22:586-594 pubmed publisher
  12. Safaiyan S, Besson Girard S, Kaya T, Cantuti Castelvetri L, Liu L, Ji H, et al. White matter aging drives microglial diversity. Neuron. 2021;109:1100-1117.e10 pubmed publisher
  13. Sobue A, Komine O, Hara Y, Endo F, Mizoguchi H, Watanabe S, et al. Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:1 pubmed publisher
  14. Zhan L, Fan L, Kodama L, Sohn P, Wong M, Mousa G, et al. A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain. elife. 2020;9: pubmed publisher
  15. BURNS J, Cotleur B, Walther D, Bajrami B, Rubino S, Wei R, et al. Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. elife. 2020;9: pubmed publisher
  16. McKinsey G, Lizama C, Keown Lang A, Niu A, Santander N, Larpthaveesarp A, et al. A new genetic strategy for targeting microglia in development and disease. elife. 2020;9: pubmed publisher
  17. Sebastian Monasor L, Müller S, Colombo A, Tanrioever G, König J, Roth S, et al. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. elife. 2020;9: pubmed publisher
  18. Dudiki T, Meller J, Mahajan G, Liu H, Zhevlakova I, Stefl S, et al. Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics. Nat Commun. 2020;11:986 pubmed publisher
  19. Plemel J, Stratton J, Michaels N, Rawji K, Zhang E, Sinha S, et al. Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion. Sci Adv. 2020;6:eaay6324 pubmed publisher
  20. Williams G, Marmion D, Schonhoff A, Jurkuvenaite A, Won W, Standaert D, et al. T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease. Acta Neuropathol. 2020;139:855-874 pubmed publisher
  21. Mathiesen Janiurek M, Soylu Kucharz R, Christoffersen C, Kucharz K, Lauritzen M. Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis. elife. 2019;8: pubmed publisher
  22. Ohgomori T, Jinno S. The expression of keratan sulfate reveals a unique subset of microglia in the mouse hippocampus after pilocarpine-induced status epileptics. J Comp Neurol. 2020;528:14-31 pubmed publisher
  23. Garcia Agudo L, Janova H, Sendler L, Arinrad S, Steixner A, Hassouna I, et al. Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. FASEB J. 2019;33:8634-8647 pubmed publisher
  24. Bertrand L, Méroth F, Tournebize M, Leda A, Sun E, Toborek M. Targeting the HIV-infected brain to improve ischemic stroke outcome. Nat Commun. 2019;10:2009 pubmed publisher
  25. Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed publisher
  26. Jordão M, Sankowski R, Brendecke S, Sagar -, Locatelli G, Tai Y, et al. Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation. Science. 2019;363: pubmed publisher
  27. Ma W, Silverman S, Zhao L, Villasmil R, Campos M, Amaral J, et al. Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization. elife. 2019;8: pubmed publisher
  28. Niu F, Liao K, Hu G, Sil S, Callen S, Guo M, et al. Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS. J Cell Biol. 2019;218:700-721 pubmed publisher
  29. Li Q, Cheng Z, Zhou L, Darmanis S, Neff N, Okamoto J, et al. Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing. Neuron. 2019;101:207-223.e10 pubmed publisher
  30. Norris G, Smirnov I, Filiano A, Shadowen H, Cody K, Thompson J, et al. Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury. J Exp Med. 2018;215:1789-1801 pubmed publisher
  31. Appel J, Ye S, Tang F, Sun D, Zhang H, Mei L, et al. Increased Microglial Activity, Impaired Adult Hippocampal Neurogenesis, and Depressive-like Behavior in Microglial VPS35-Depleted Mice. J Neurosci. 2018;38:5949-5968 pubmed publisher
  32. Zrzavy T, Hoftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, et al. Pro-inflammatory activation of microglia in the brain of patients with sepsis. Neuropathol Appl Neurobiol. 2019;45:278-290 pubmed publisher