This is a Validated Antibody Database (VAD) review about human TLR8, based on 7 published articles (read how Labome selects the articles), using TLR8 antibody in all methods. It is aimed to help Labome visitors find the most suited TLR8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TLR8 synonym: CD288; toll-like receptor 8

Invitrogen
mouse monoclonal (44C143)
  • flow cytometry; human; fig 1
In order to investigate the expression of Toll-like receptors in satellite glial cells, Invitrogen TLR8 antibody (Thermo Fischer Scientific, 44C143) was used in flow cytometry on human samples (fig 1). Eur J Immunol (2017) ncbi
mouse monoclonal (44C143)
  • flow cytometry; human; fig 1c
In order to evaluate combinations of TLR and C-type lectin receptor agonists on the Th1 responses of newborn dendritic cells, Invitrogen TLR8 antibody (Thermo Scientific, 44C143) was used in flow cytometry on human samples (fig 1c). J Immunol (2016) ncbi
Novus Biologicals
mouse monoclonal (44C143)
  • immunohistochemistry; human; 1:850; loading ...; fig 2h
  • western blot; human; 1:850; loading ...; fig s1
  • immunohistochemistry; mouse; 1:850; loading ...; fig 3h
  • western blot; mouse; 1:850; loading ...; fig s1
Novus Biologicals TLR8 antibody (Novus Biologicals, NBP2-24917) was used in immunohistochemistry on human samples at 1:850 (fig 2h), in western blot on human samples at 1:850 (fig s1), in immunohistochemistry on mouse samples at 1:850 (fig 3h) and in western blot on mouse samples at 1:850 (fig s1). J Histochem Cytochem (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-8)
  • western blot; human; 1:300; fig s1
Santa Cruz Biotechnology TLR8 antibody (Santa Cruz, sc-373760) was used in western blot on human samples at 1:300 (fig s1). Sci Rep (2016) ncbi
Abcam
mouse monoclonal (44C143)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, Abcam TLR8 antibody (Abcam, ab45097) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
Sigma-Aldrich
mouse monoclonal (4C6)
  • western blot; human; loading ...; fig 2a
Sigma-Aldrich TLR8 antibody (Sigma, 4C6) was used in western blot on human samples (fig 2a). PLoS Pathog (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D3Z6J)
  • blocking or activating experiments; human
Cell Signaling Technology TLR8 antibody (Cell Signaling Technology, D3Z6J) was used in blocking or activating experiments on human samples . PLoS Pathog (2014) ncbi
Articles Reviewed
  1. Mitterreiter J, Ouwendijk W, van Velzen M, van Nierop G, Osterhaus A, Verjans G. Satellite glial cells in human trigeminal ganglia have a broad expression of functional Toll-like receptors. Eur J Immunol. 2017;47:1181-1187 pubmed publisher
  2. van Haren S, Dowling D, Foppen W, Christensen D, Andersen P, Reed S, et al. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016;197:4413-4424 pubmed
  3. Huhta H, Helminen O, Kauppila J, Salo T, Porvari K, Saarnio J, et al. The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer. J Histochem Cytochem. 2016;64:470-82 pubmed publisher
  4. He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, et al. The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. Sci Rep. 2016;6:27597 pubmed publisher
  5. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  6. Campbell G, Rawat P, Bruckman R, Spector S. Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration. PLoS Pathog. 2015;11:e1005018 pubmed publisher
  7. Chattergoon M, Latanich R, Quinn J, Winter M, Buckheit R, Blankson J, et al. HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon. PLoS Pathog. 2014;10:e1004082 pubmed publisher