This is a Validated Antibody Database (VAD) review about human TIMP-3, based on 6 published articles (read how Labome selects the articles), using TIMP-3 antibody in all methods. It is aimed to help Labome visitors find the most suited TIMP-3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TIMP-3 synonym: HSMRK222; K222; K222TA2; SFD

Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s4d
Abcam TIMP-3 antibody (Abcam, ab39184) was used in western blot on mouse samples (fig s4d). Clin Transl Med (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 2b
Abcam TIMP-3 antibody (Abcam, ab39184) was used in western blot on rat samples (fig 2b). J Neurosci (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:100; fig 5a
In order to test if the leptomeningeal arteries derived from patients with cerebral amyloid angiopathy have a distinct endophenotypic profile compared to those from young and elderly controls, Abcam TIMP-3 antibody (Abcam, Ab93637) was used in immunohistochemistry on human samples at 1:100 (fig 5a). Neuropathol Appl Neurobiol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-2)
  • western blot; human; fig 5a
Santa Cruz Biotechnology TIMP-3 antibody (Santa Cruz, sc-373839) was used in western blot on human samples (fig 5a). J Am Heart Assoc (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D74B10)
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 1d
  • western blot; rat; 1:1000; loading ...; fig 1f
Cell Signaling Technology TIMP-3 antibody (Cell Signaling, 5673S) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 1d) and in western blot on rat samples at 1:1000 (fig 1f). Exp Ther Med (2021) ncbi
domestic rabbit monoclonal (D74B10)
  • western blot; human; 1:1000; fig 6
In order to study the role of normal and tumor-associated fibroblasts in the pathogenesis of cervical cancer, Cell Signaling Technology TIMP-3 antibody (Cell Signaling, 5673) was used in western blot on human samples at 1:1000 (fig 6). BMC Cancer (2015) ncbi
Articles Reviewed
  1. Meng L, Zhang Y, Li D, Shang X, Hao X, Chen X, et al. TIMP3 attenuates cerebral ischemia/reperfusion-induced apoptosis and oxidative stress in neurocytes by regulating the AKT pathway. Exp Ther Med. 2021;22:973 pubmed publisher
  2. Casagrande V, Iuliani G, Menini S, Pugliese G, Federici M, Menghini R. Restoration of renal TIMP3 levels via genetics and pharmacological approach prevents experimental diabetic nephropathy. Clin Transl Med. 2021;11:e305 pubmed publisher
  3. Rempe R, Hartz A, Soldner E, Sokola B, Alluri S, Abner E, et al. Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy. J Neurosci. 2018;38:4301-4315 pubmed publisher
  4. Du M, Wang X, Tan X, Li X, Huang D, Huang K, et al. Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed
  5. Manousopoulou A, Gatherer M, Smith C, Nicoll J, Woelk C, Johnson M, et al. Systems proteomic analysis reveals that clusterin and tissue inhibitor of metalloproteinases 3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy. Neuropathol Appl Neurobiol. 2017;43:492-504 pubmed publisher
  6. Fullár A, Dudás J, Oláh L, Hollósi P, Papp Z, Sobel G, et al. Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression. BMC Cancer. 2015;15:256 pubmed publisher