This is a Validated Antibody Database (VAD) review about human TIMP-1, based on 28 published articles (read how Labome selects the articles), using TIMP-1 antibody in all methods. It is aimed to help Labome visitors find the most suited TIMP-1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TIMP-1 synonym: CLGI; EPA; EPO; HCI; TIMP; TIMP-1

Santa Cruz Biotechnology
mouse monoclonal (2A5)
  • western blot; mouse; 1:1000; loading ...; fig 2b
Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz, sc-21734) was used in western blot on mouse samples at 1:1000 (fig 2b). BMC Med (2022) ncbi
mouse monoclonal (2A5)
  • western blot; mouse; loading ...; fig 4h
Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz, sc-21734) was used in western blot on mouse samples (fig 4h). Sci Adv (2021) ncbi
mouse monoclonal (2A5)
  • western blot; pigs ; 1:400; loading ...; fig 4d
Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz Biotechnology, sc21734) was used in western blot on pigs samples at 1:400 (fig 4d). Sci Rep (2021) ncbi
mouse monoclonal (2A5)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz, sc-21734) was used in immunohistochemistry - paraffin section on mouse samples (fig 6a). Cardiovasc Diabetol (2018) ncbi
mouse monoclonal (2A5)
  • western blot; rat; 1:500; fig 8
Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz, SC21734) was used in western blot on rat samples at 1:500 (fig 8). Int J Mol Med (2015) ncbi
mouse monoclonal (G-6)
  • western blot; human
Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz Biotechnology, sc-365905) was used in western blot on human samples . J Leukoc Biol (2014) ncbi
mouse monoclonal (G-6)
  • western blot; human
In order to study the relationship between SPAG9 and PODXL in human astrocytoma invasion, Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz Biotechnology, sc-365905) was used in western blot on human samples . Mol Med Rep (2014) ncbi
mouse monoclonal (2A5)
  • western blot; domestic rabbit; 1:2000
Santa Cruz Biotechnology TIMP-1 antibody (Santa Cruz Biotechnology, sc-21734) was used in western blot on domestic rabbit samples at 1:2000. Exp Ther Med (2014) ncbi
Invitrogen
mouse monoclonal (F31 P2 A5)
  • western blot; mouse; loading ...; fig 4b
Invitrogen TIMP-1 antibody (Thermo Fisher Scientific, MA1-773) was used in western blot on mouse samples (fig 4b). Molecules (2019) ncbi
mouse monoclonal (102D1)
  • other; human; loading ...; fig s1
In order to investigate the mechanisms of toxicity by the negative allosteric modulators of metabotropic glutamate receptor 5, Invitrogen TIMP-1 antibody (Thermo Fisher, MS-608-p0) was used in other on human samples (fig s1). Cell Chem Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig s5a
In order to determine the impact of smooth muscle cell beta-catenin to vascular homeostasis and arterial injury, Invitrogen TIMP-1 antibody (Thermo fisher, PA5-13668) was used in western blot on mouse samples at 1:2000 (fig s5a). Arterioscler Thromb Vasc Biol (2017) ncbi
mouse monoclonal (F31 P2 A5)
  • western blot; mouse; fig 3
In order to infer a RANKL-dependent osteoclastogenesis after debridement of osteomyelitis coinciding with elevated B cells and simultaneously decreased osteogenesis, Invitrogen TIMP-1 antibody (Thermo Fisher Scientific, MA1-773) was used in western blot on mouse samples (fig 3). J Orthop Res (2017) ncbi
mouse monoclonal (F31 P2 A5)
  • western blot; mouse; 1:500; loading ...; fig 6
In order to study the effect of intranasal curcumin on airway remodeling and fibrosis in murine model of chronic asthma, Invitrogen TIMP-1 antibody (Thermo Scientific, MA1-773) was used in western blot on mouse samples at 1:500 (fig 6). Inflammation (2017) ncbi
mouse monoclonal (102D1)
  • immunohistochemistry - paraffin section; human; 1:100; tbl 2
In order to study the clinical significance and expression of metalloproteases and their inhibitors in invasive breast carcinoma endothelial cells, Invitrogen TIMP-1 antibody (Thermo, MA5-13688) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 2). Clin Breast Cancer (2016) ncbi
mouse monoclonal (102D1)
  • immunohistochemistry; human
In order to determine the prognostic and predictive role of topoisomerase IIalpha and tissue inhibitor of metalloproteinases 1 in patient with locally advanced breast cancer after anthracycline-based neoadjuvant chemotherapy, Invitrogen TIMP-1 antibody (Labvision, MS-608-PCL) was used in immunohistochemistry on human samples . Appl Immunohistochem Mol Morphol (2016) ncbi
mouse monoclonal (102D1)
  • immunohistochemistry; human; 1:25
Invitrogen TIMP-1 antibody (Thermo Fisher Scientific, 102D1) was used in immunohistochemistry on human samples at 1:25. BMC Cancer (2014) ncbi
mouse monoclonal (102D1)
  • immunohistochemistry - paraffin section; human; 1:600
In order to look for an association between Chlamydophila pneumoniae, Mycoplasma pneumoniae, matrix metalloproteinase 9, and tissue inhibitor of metalloproteinase 1 in aneurysmatic atherosclerotic lesions, and atherosclerotic nonaneurysmatic lesions, Invitrogen TIMP-1 antibody (Neo Markers, 102D1) was used in immunohistochemistry - paraffin section on human samples at 1:600. Ann Vasc Surg (2013) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:5000; loading ...; fig 5e
Abcam TIMP-1 antibody (Abcam, ab38978) was used in western blot on mouse samples at 1:5000 (fig 5e). Aging (Albany NY) (2019) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 2b
Abcam TIMP-1 antibody (Abcam, ab61224) was used in western blot on rat samples (fig 2b). J Neurosci (2018) ncbi
domestic rabbit monoclonal (EPR1550)
  • western blot; human; loading ...; fig 3c
Abcam TIMP-1 antibody (Abcam, ab109125) was used in western blot on human samples (fig 3c). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR1550)
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1c, 1g
Abcam TIMP-1 antibody (Abcam, ab109125) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1c, 1g). Onco Targets Ther (2016) ncbi
R&D Systems
domestic goat polyclonal
  • western blot; human; fig 1d
R&D Systems TIMP-1 antibody (R&D Systems, AF970) was used in western blot on human samples (fig 1d). Cell Rep (2019) ncbi
domestic goat polyclonal
  • western blot; human; 1:600; loading ...; fig 4
In order to test if a period of additional speed endurance training improves intense intermittent exercise performance in highly trained soccer players, R&D Systems TIMP-1 antibody (R&D Systems, AF 970) was used in western blot on human samples at 1:600 (fig 4). Med Sci Sports Exerc (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D10E6)
  • western blot; human; 1:1000; loading ...; fig 3g
Cell Signaling Technology TIMP-1 antibody (Cell Signaling, 8946) was used in western blot on human samples at 1:1000 (fig 3g). Mol Cancer Res (2021) ncbi
domestic rabbit monoclonal (D10E6)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology TIMP-1 antibody (cell signalling, 8946) was used in western blot on human samples (fig 7a). Int J Mol Sci (2016) ncbi
domestic rabbit monoclonal (D10E6)
  • western blot; human; 1:1000; fig 6
In order to study the role of normal and tumor-associated fibroblasts in the pathogenesis of cervical cancer, Cell Signaling Technology TIMP-1 antibody (Cell Signaling, 8946) was used in western blot on human samples at 1:1000 (fig 6). BMC Cancer (2015) ncbi
Dako
mouse monoclonal (VT7)
  • immunohistochemistry; human; 1:50; fig 1
Dako TIMP-1 antibody (Dako, VT7) was used in immunohistochemistry on human samples at 1:50 (fig 1). J Oral Pathol Med (2015) ncbi
MilliporeSigma
mouse monoclonal (4D12)
  • western blot; human; loading ...; fig 6b, 6d, 6h
MilliporeSigma TIMP-1 antibody (Sigma-Aldrich, WH0007076M1) was used in western blot on human samples (fig 6b, 6d, 6h). Aging (Albany NY) (2019) ncbi
Articles Reviewed
  1. Chen T, Shi Z, Zhao Y, Meng X, Zhao S, Zheng L, et al. LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway. BMC Med. 2022;20:335 pubmed publisher
  2. Xi Y, Li Y, Xu P, Li S, Liu Z, Tung H, et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv. 2021;7:eabg9241 pubmed publisher
  3. Ziecik A, Klos J, Gromadzka Hliwa K, Dietrich M, Slowinska M, Likszo P, et al. Endocrine and molecular milieus of ovarian follicles are diversely affected by human chorionic gonadotropin and gonadotropin-releasing hormone in prepubertal and mature gilts. Sci Rep. 2021;11:13465 pubmed publisher
  4. Sanchez D, Missiaen R, Skuli N, Steger D, Simon M. Cell-Intrinsic Tumorigenic Functions of PPARγ in Bladder Urothelial Carcinoma. Mol Cancer Res. 2021;19:598-611 pubmed publisher
  5. Yang Y, Tang F, Wei F, Yang L, Kuang C, Zhang H, et al. Silencing of long non-coding RNA H19 downregulates CTCF to protect against atherosclerosis by upregulating PKD1 expression in ApoE knockout mice. Aging (Albany NY). 2019;11:10016-10030 pubmed publisher
  6. Yang L, Jiang Q, Li D, Zhou X, Yu D, Zhong J. TIMP1 mRNA in tumor-educated platelets is diagnostic biomarker for colorectal cancer. Aging (Albany NY). 2019;11:8998-9012 pubmed publisher
  7. Wiley C, Liu S, Limbad C, Zawadzka A, Beck J, Demaria M, et al. SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Cell Rep. 2019;28:3329-3337.e5 pubmed publisher
  8. Yi R, Zhang J, Sun P, Qian Y, Zhao X. Protective Effects of Kuding Tea (Ilex kudingcha C. J. Tseng) Polyphenols on UVB-Induced Skin Aging in SKH1 Hairless Mice. Molecules. 2019;24: pubmed publisher
  9. Nasiri Ansari Ν, Dimitriadis G, Agrogiannis G, Perrea D, Kostakis I, Kaltsas G, et al. Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice. Cardiovasc Diabetol. 2018;17:106 pubmed publisher
  10. Rempe R, Hartz A, Soldner E, Sokola B, Alluri S, Abner E, et al. Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy. J Neurosci. 2018;38:4301-4315 pubmed publisher
  11. Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
  12. Riascos Bernal D, Chinnasamy P, Gross J, Almonte V, Egaña Gorroño L, Parikh D, et al. Inhibition of Smooth Muscle ?-Catenin Hinders Neointima Formation After Vascular Injury. Arterioscler Thromb Vasc Biol. 2017;37:879-888 pubmed publisher
  13. Wagner J, Jaurich H, Wallner C, Abraham S, Becerikli M, Dadras M, et al. Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity. J Orthop Res. 2017;35:2425-2434 pubmed publisher
  14. Chauhan P, Dash D, Singh R. Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma. Inflammation. 2017;40:248-258 pubmed publisher
  15. Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
  16. Lu X, Duan L, Xie H, Lu X, Lu D, Lu D, et al. Evaluation of MMP-9 and MMP-2 and their suppressor TIMP-1 and TIMP-2 in adenocarcinoma of esophagogastric junction. Onco Targets Ther. 2016;9:4343-9 pubmed publisher
  17. Cid S, Eiró N, Gonzalez L, Béridze N, Vazquez J, Vizoso F. Expression and Clinical Significance of Metalloproteases and Their Inhibitors by Endothelial Cells From Invasive Breast Carcinomas. Clin Breast Cancer. 2016;16:e83-91 pubmed publisher
  18. Wang X, Wang N, Li H, Liu M, Cao F, Yu X, et al. Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. Int J Mol Sci. 2016;17:577 pubmed publisher
  19. Nyberg M, Fiorenza M, Lund A, Christensen M, Rømer T, Piil P, et al. Adaptations to Speed Endurance Training in Highly Trained Soccer Players. Med Sci Sports Exerc. 2016;48:1355-64 pubmed publisher
  20. Yan G, Wang Q, Hu S, Wang D, Qiao Y, Ma G, et al. Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med. 2015;36:1001-11 pubmed publisher
  21. Fullár A, Dudás J, Oláh L, Hollósi P, Papp Z, Sobel G, et al. Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression. BMC Cancer. 2015;15:256 pubmed publisher
  22. El Rebey H, Aiad H, Abulkheir I, Asaad N, El Wahed M, Abulkasem F, et al. The Predictive and Prognostic Role of Topoisomerase IIα and Tissue Inhibitor of Metalloproteinases 1 Expression in Locally Advanced Breast Carcinoma of Egyptian Patients Treated With Anthracycline-based Neoadjuvant Chemotherapy. Appl Immunohistochem Mol Morphol. 2016;24:167-78 pubmed publisher
  23. Kim G, Lee J, Choi Y, Lee K, Lee J, Nam J, et al. Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer. BMC Cancer. 2014;14:959 pubmed publisher
  24. Bodnar M, Szylberg Ł, Kazmierczak W, Marszalek A. Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors. J Oral Pathol Med. 2015;44:437-43 pubmed publisher
  25. Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher
  26. Jiang J, Liu Y, Fang W, Liu F. Sperm?associated antigen 9 promotes astrocytoma cell invasion through the upregulation of podocalyxin. Mol Med Rep. 2014;10:417-22 pubmed publisher
  27. Wang L, Wang J, Wang Y, Fu Q, Lei Y, Nie Z, et al. Protective effect of exogenous matrix metalloproteinase-9 on chronic renal failure. Exp Ther Med. 2014;7:329-334 pubmed
  28. Roggério A, Sambiase N, Palomino S, de Castro M, da Silva E, Stolf N, et al. Correlation of bacterial coinfection versus matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 expression in aortic aneurysm and atherosclerosis. Ann Vasc Surg. 2013;27:964-71 pubmed publisher