This is a Validated Antibody Database (VAD) review about human TIGAR, based on 7 published articles (read how Labome selects the articles), using TIGAR antibody in all methods. It is aimed to help Labome visitors find the most suited TIGAR antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TIGAR synonym: C12orf5; FR2BP

Knockout validation
Abcam
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; human; 1:200; fig 4d
  • western blot; human; 1:200; loading ...; fig 3g
Abcam TIGAR antibody (Abcam, ab62533) was used in immunohistochemistry knockout validation on human samples at 1:200 (fig 4d) and in western blot on human samples at 1:200 (fig 3g). Theranostics (2020) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; human; 1:200; fig 4d
  • western blot; human; 1:200; loading ...; fig 3g
Abcam TIGAR antibody (Abcam, ab62533) was used in immunohistochemistry knockout validation on human samples at 1:200 (fig 4d) and in western blot on human samples at 1:200 (fig 3g). Theranostics (2020) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Abcam TIGAR antibody (Abcam, ab137573) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3g
In order to test if LKB1 mutations contribute to cervical cancer initiation and progress, Abcam TIGAR antibody (Abcam, ab37910) was used in western blot on mouse samples (fig 3g). Oncogene (2017) ncbi
domestic rabbit polyclonal
Abcam TIGAR antibody (Abcam, ab37910) was used . Sci Rep (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-10)
  • immunohistochemistry - paraffin section; human; 1:100; fig 3
Santa Cruz Biotechnology TIGAR antibody (santa Cruz, sc-166291) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3). Oncol Rep (2016) ncbi
mouse monoclonal (F-5)
  • western blot; human; fig 5
Santa Cruz Biotechnology TIGAR antibody (Santa Cruz, sc-377065) was used in western blot on human samples (fig 5). Mol Med Rep (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; fig 4b
Invitrogen TIGAR antibody (Invitrogen, PA5-23053) was used in western blot on mouse samples (fig 4b). Cell (2018) ncbi
Articles Reviewed
  1. Chu J, Niu X, Chang J, Shao M, Peng L, Xi Y, et al. Metabolic remodeling by TIGAR overexpression is a therapeutic target in esophageal squamous-cell carcinoma. Theranostics. 2020;10:3488-3502 pubmed publisher
  2. Xiao G, Chan L, Klemm L, Braas D, Chen Z, Geng H, et al. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018;173:470-484.e18 pubmed publisher
  3. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  4. Zeng Q, Chen J, Li Y, Werle K, Zhao R, Quan C, et al. LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism. Oncogene. 2017;36:1245-1255 pubmed publisher
  5. Al Khayal K, Abdulla M, Al Obeed O, Al Kattan W, Zubaidi A, Vaali Mohammed M, et al. Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients. Oncol Rep. 2016;35:1281-6 pubmed publisher
  6. Shi X, Xiong L, Xiao L, Meng C, Qi G, Li W. Downregulation of caveolin‑1 upregulates the expression of growth factors and regulators in co‑culture of fibroblasts with cancer cells. Mol Med Rep. 2016;13:744-52 pubmed publisher
  7. Yu H, Xie J, Li B, Sun Y, Gao Q, Ding Z, et al. TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway. Sci Rep. 2015;5:9853 pubmed publisher