This is a Validated Antibody Database (VAD) review about human THRB, based on 15 published articles (read how Labome selects the articles), using THRB antibody in all methods. It is aimed to help Labome visitors find the most suited THRB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
THRB synonym: C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; PRTH; THR1; THRB1; THRB2; thyroid hormone receptor beta; nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)

Santa Cruz Biotechnology
mouse monoclonal (J53)
  • western blot; human; loading ...; fig 1c
Santa Cruz Biotechnology THRB antibody (SantaCruz, sc-56872) was used in western blot on human samples (fig 1c). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (C1)
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology THRB antibody (Santa Cruz Biotechnology, sc-739) was used in western blot on human samples (fig 1b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (J52)
  • western blot; mouse; loading ...; fig 3a
  • western blot; human; loading ...; fig s3
In order to investigate the levels of hepatic TR beta, lipogenic gene, and long chain acylcarnitine during chronic hyperthyroidism, Santa Cruz Biotechnology THRB antibody (Santa Cruz Biotechnology, sc-738) was used in western blot on mouse samples (fig 3a) and in western blot on human samples (fig s3). Thyroid (2017) ncbi
mouse monoclonal (J52)
  • flow cytometry; human; fig 5d
  • western blot; human; fig 5c
In order to see if tetraspanin 8 influences cell-matrix anchorage and regulates downstream molecular pathways leading to aggressive behavior of tumor progression in melanoma, Santa Cruz Biotechnology THRB antibody (Santa Cruz, sc-738) was used in flow cytometry on human samples (fig 5d) and in western blot on human samples (fig 5c). Oncotarget (2017) ncbi
mouse monoclonal (J52)
  • immunocytochemistry; human; 1:250; loading ...; fig s3
In order to define specific role for thyroid hormone receptor alpha and beta, Santa Cruz Biotechnology THRB antibody (Santa Cruz, sc-738) was used in immunocytochemistry on human samples at 1:250 (fig s3). PLoS ONE (2016) ncbi
mouse monoclonal (C4)
  • chromatin immunoprecipitation; mouse; fig 2
Santa Cruz Biotechnology THRB antibody (Santa Cruz, sc-740) was used in chromatin immunoprecipitation on mouse samples (fig 2). J Cell Biol (2014) ncbi
mouse monoclonal (J52)
  • western blot; mouse
Santa Cruz Biotechnology THRB antibody (Santa Cruz Biotechnology, sc-738) was used in western blot on mouse samples . In Vitro Cell Dev Biol Anim (2014) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 1
  • chromatin immunoprecipitation; human; fig 6
In order to characterize a novel signaling pathway in thyroid cancer that mediates runt-related transcription factor 2 (Runx2) expression in thyroid cancer cells by thyroid hormone receptor beta (TRbeta), Invitrogen THRB antibody (Thermo Scientific, PA5-29 684) was used in immunohistochemistry - paraffin section on human samples (fig 1) and in chromatin immunoprecipitation on human samples (fig 6). Endocrinology (2016) ncbi
mouse monoclonal (J52)
  • western blot; mouse
In order to investigate thyroid hormone receptor in adipogenesis, Invitrogen THRB antibody (ThermoFisher Scientific, MA1-216) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse
In order to elucidate the regulatory mechanisms of FGF21 expression by triiodothyronine and test if FGF21 is required for induction of hepatic triiodothyronine-responsive genes, Invitrogen THRB antibody (Thermoscientific, PA1-213A) was used in chromatin immunoprecipitation on mouse samples . J Endocrinol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100
In order to study the effect of thyroid hormone on hair growth and skin homeostasis, Invitrogen THRB antibody (Affinity BioReagents, PA1-213A) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. PLoS ONE (2014) ncbi
mouse monoclonal (J52)
  • chromatin immunoprecipitation; rat
In order to study the mechanism by which thyroid hormone T3 inhibits the expression of secretory phospholipase A2 group IIa, Invitrogen THRB antibody (Thermo Scientific, MA1-216) was used in chromatin immunoprecipitation on rat samples . J Biol Chem (2013) ncbi
mouse monoclonal (C3)
  • western blot; common platanna; 1:1000
In order to investigate the role of thyroid hormone receptors in apoptosis, Invitrogen THRB antibody (Affinity Bioreagents, MA1- 215) was used in western blot on common platanna samples at 1:1000. Apoptosis (2007) ncbi
Abcam
rabbit polyclonal
  • immunocytochemistry; mouse; fig 7
In order to identify modulators of corticotropin-releasing hormone receptor type 1 signaling, Abcam THRB antibody (Abcam, ab5622) was used in immunocytochemistry on mouse samples (fig 7). PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:500; loading ...; fig 5b2
Abcam THRB antibody (Abcam, Ab5622) was used in immunohistochemistry on human samples at 1:500 (fig 5b2). J Mol Neurosci (2015) ncbi
Articles Reviewed
  1. Gao X, Lee H, Li W, Platt R, Barrasa M, Ma Q, et al. Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. Proc Natl Acad Sci U S A. 2017;114:10107-10112 pubmed publisher
  2. Guan W, Guyot R, Samarut J, Flamant F, Wong J, Gauthier K. Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin. Proc Natl Acad Sci U S A. 2017;114:8229-8234 pubmed publisher
  3. Ohba K, Sinha R, Singh B, Iannucci L, Zhou J, Kovalik J, et al. Changes in Hepatic TR? Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model. Thyroid. 2017;27:852-860 pubmed publisher
  4. El Kharbili M, Robert C, Witkowski T, Danty Berger E, Barbollat Boutrand L, Masse I, et al. Tetraspanin 8 is a novel regulator of ILK-driven ?1 integrin adhesion and signaling in invasive melanoma cells. Oncotarget. 2017;8:17140-17155 pubmed publisher
  5. Cvoro A, Bajić A, Zhang A, Simon M, Golic I, Sieglaff D, et al. Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells. PLoS ONE. 2016;11:e0164407 pubmed publisher
  6. CARR F, Tai P, Barnum M, Gillis N, Evans K, Taber T, et al. Thyroid Hormone Receptor-? (TR?) Mediates Runt-Related Transcription Factor 2 (Runx2) Expression in Thyroid Cancer Cells: A Novel Signaling Pathway in Thyroid Cancer. Endocrinology. 2016;157:3278-92 pubmed publisher
  7. Bender J, Engeholm M, Ederer M, Breu J, Møller T, Michalakis S, et al. Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif. PLoS ONE. 2015;10:e0136768 pubmed publisher
  8. Liu Y, AYERS S, Milanesi A, Teng X, Rabi S, Akiba Y, et al. Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation. J Biol Chem. 2015;290:7402-15 pubmed publisher
  9. Zhang D, Wang X, Li Y, Zhao L, Lu M, Yao X, et al. Thyroid hormone regulates muscle fiber type conversion via miR-133a1. J Cell Biol. 2014;207:753-66 pubmed publisher
  10. Zhang A, Sieglaff D, York J, Suh J, Ayers S, Winnier G, et al. Thyroid hormone receptor regulates most genes independently of fibroblast growth factor 21 in liver. J Endocrinol. 2015;224:289-301 pubmed publisher
  11. Contreras Jurado C, García Serrano L, Martínez Fernández M, Ruiz Llorente L, Paramio J, Aranda A. Impaired hair growth and wound healing in mice lacking thyroid hormone receptors. PLoS ONE. 2014;9:e108137 pubmed publisher
  12. Alvarez A, Field M, Bushnev S, Longo M, Sugaya K. The effects of histone deacetylase inhibitors on glioblastoma-derived stem cells. J Mol Neurosci. 2015;55:7-20 pubmed publisher
  13. Tamaki S, Tokumoto Y. Overexpression of cyclin dependent kinase inhibitor P27/Kip1 increases oligodendrocyte differentiation from induced pluripotent stem cells. In Vitro Cell Dev Biol Anim. 2014;50:778-85 pubmed publisher
  14. Sharma P, Thakran S, Deng X, Elam M, Park E. Nuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormone. J Biol Chem. 2013;288:16321-33 pubmed publisher
  15. Saelim N, Holstein D, Chocron E, Camacho P, Lechleiter J. Inhibition of apoptotic potency by ligand stimulated thyroid hormone receptors located in mitochondria. Apoptosis. 2007;12:1781-94 pubmed